Noriko Okamoto

ORCID: 0000-0001-5493-8051
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About
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Research Areas
  • Protist diversity and phylogeny
  • Microbial Community Ecology and Physiology
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Catalytic Alkyne Reactions
  • Catalytic C–H Functionalization Methods
  • Synthetic Organic Chemistry Methods
  • Asymmetric Synthesis and Catalysis
  • Cyclopropane Reaction Mechanisms
  • Synthesis and Catalytic Reactions
  • Oxidative Organic Chemistry Reactions
  • Genomics and Phylogenetic Studies
  • Marine Biology and Ecology Research
  • Chemical Synthesis and Analysis
  • Marine and coastal ecosystems
  • Asymmetric Hydrogenation and Catalysis
  • Synthesis and Biological Activity
  • Click Chemistry and Applications
  • Protein Hydrolysis and Bioactive Peptides
  • Analytical chemistry methods development
  • Fluorine in Organic Chemistry
  • Insect and Arachnid Ecology and Behavior
  • Crystallography and molecular interactions
  • Plant and animal studies
  • Environmental DNA in Biodiversity Studies

Hakai Institute
2022-2024

University of British Columbia
2014-2024

Tula Foundation
2022-2024

University of Tsukuba
2003-2020

Hiroshima International University
2010-2019

Hiroshima University
2006-2016

California Institute of Technology
2015-2016

Canadian Institute for Advanced Research
2011-2015

Health Sciences University of Hokkaido
2013

Jichi Medical University
1986-2013

The diurnal cycle of rainfall and its regional variation over Sumatera Island, Indonesian Maritime Continent, are examined using Tropical Rainfall Measuring Mission (TRMM) satellite precipitation radar (PR) intensive rawinsonde sounding data. TRMM PR sensor can detect raindrops directly, regardless ground cloud conditions, distinguish between convective stratiform types rainfall. this area was found to have the following characteristics: 1) with a broad peak 1500 2000 LT predominates land...

10.1175/1520-0493(2004)132<2021:dlrpmo>2.0.co;2 article EN other-oa Monthly Weather Review 2004-08-01

An important missing piece in the puzzle of how plastids spread across eukaryotic tree life is a robust evolutionary framework for host lineages. Four assemblages are known to harbour derived from red algae and, according controversial chromalveolate hypothesis, these all share common ancestry. Phylogenomic analyses have consistently shown that stramenopiles and alveolates closely related, but haptophytes cryptophytes remain contentious; they been proposed branch together with several...

10.1098/rspb.2011.2301 article EN Proceedings of the Royal Society B Biological Sciences 2012-02-01

A catalytic, enantioselective γ-alkylation of α,β-unsaturated malonates and ketoesters is reported. This strategy entails a highly regio- iridium-catalyzed α-alkylation an extended enolate, subsequent translocation chirality to the γ-position via Cope rearrangement.

10.1021/jacs.6b02153 article EN Journal of the American Chemical Society 2016-04-07

Algae have acquired plastids by developing an endosymbiotic relationship with either a cyanobacterium (primary endosymbiosis) or other eukaryotic algae (secondary endosymbiosis). We report protist, which we tentatively refer to as Hatena, that hosts green algal partner but inherits it unevenly. The endosymbiosis causes drastic morphological changes both the symbiont and host cell architecture. This type of life cycle, in endosymbiont integration has only partially converted from predator...

10.1126/science.1116125 article EN Science 2005-10-13

Photosynthetic eukaryotes with a secondary plastid of red algal origin (cryptophytes, haptophytes, stramenopiles, dinoflagellates, and apicomplexans) are hypothesized to share single acquisition according Chromalveolate hypothesis. Recent phylogenomic analyses suggest that photosynthetic "chromalveolates" form large clade inclusion several non-photosynthetic protist lineages. Katablepharids one such lineage closely related cryptophytes. Despite their evolutionary ecological importance,...

10.1371/journal.pone.0007080 article EN cc-by PLoS ONE 2009-09-16

ADVERTISEMENT RETURN TO ISSUELetterNEXTCleavage of Carbon–Carbon Triple Bond: Direct Transformation Alkynes to NitrilesNoriko Okamoto†, Minoru Ishikura‡, and Reiko Yanada*†View Author Information Faculty Pharmaceutical Sciences, Hiroshima International University, 5-1-1 Hirokoshingai, Kure, 737-0112, Japan, Health Sciences University Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan[email protected]†Hiroshima University.‡Health Hokkaido.Cite this: Org. Lett. 2013, 15, 11,...

10.1021/ol401311h article EN Organic Letters 2013-05-15

The apical complex is one of the defining features apicomplexan parasites, including malaria parasite Plasmodium, where it mediates host penetration and invasion. also known in a few related lineages, several non-parasitic heterotrophs, feeding behaviour. origin unclear, reason for this that apicomplexans exists only part life cycle, never simultaneously with other major cytoskeletal structures like flagella basal bodies. Here, we used conventional TEM serial tomography to reconstruct three...

10.1371/journal.pone.0084653 article EN cc-by PLoS ONE 2014-01-02

The microbial communities of sandy beaches are poorly described despite the biogeochemical importance and ubiquity these ecosystems. Using metabarcoding 16S 18S rRNA genes, we investigated diversity, microhabitats (with or between sand grains) intertidal distributions microorganisms (including meiofauna) from pristine in British Columbia, Canada, hypothesized that abiotic variations due to microhabitat gradients influence distribution on local scales. Bacterial, archaeal protistan were...

10.1111/mec.16453 article EN Molecular Ecology 2022-04-01

Aryl alkyl alkynes reacted with N-iodosuccinimide (NIS) and trimethylsilyl azide (TMSN3), leading to α,α-diazidoketones via the regioselective addition of IN3 alkynes. Huisgen cyclization generated bis-triazole compounds.

10.1021/acs.orglett.5b00395 article EN Organic Letters 2015-02-26

Microbial eukaryotes are important components of marine ecosystems, and the Marine Alveolates (MALVs) consistently both abundant diverse in global environmental sequencing surveys. MALVs dinoflagellates that thought to be parasites other protists animals, but lack data beyond ribosomal RNA gene sequences from all a few described species means much their biology evolution remain unknown. Using single-cell transcriptomes several free-living relatives, we show evolved independently two...

10.1038/s41467-023-42807-0 article EN cc-by Nature Communications 2023-11-03

In alveolate evolution, dinoflagellates have developed many unique features, including the cell that has epicone and hypocone, undulating transverse flagellum. However, it remains unclear how these features evolved. The early branching so far investigated such as Hematodinium, Amoebophrya Oxyrrhis marina differ in ways from of core dinoflagellates, or dinokaryotes. Except those handful well studied taxa, vast majority are known only by environmental sequences, remain enigmatic. this study we...

10.1371/journal.pone.0034900 article EN cc-by PLoS ONE 2012-06-18

Evaluation of: Moore RB, Obornik M, Janouškovec J et al.: A photosynthetic alveolate closely related to apicomplexan parasites. Nature 451(7181), 959–963 (2008). Malaria and parasites contain a relict plastid (apicoplast) that is promising drug target. The apicoplast has been argued derive from either an engulfed red or green alga. discovery of the first apicomplexan, dubbed Chromera velia, with fully functional resolves debate, clearly showing derived modified Intriguingly, C. velia coral...

10.2217/17460913.3.4.391 article EN Future Microbiology 2008-07-23

Regio- and stereoselective cohalogenation of alkynes with NXS (X = Br, I) was achieved, the stereoselectivity resulting alkenes dependent on substituent alkyne. Cohalogenation successive cross-coupling gave multisubstituted enol esters in a one-pot process.

10.1021/jo201609r article EN The Journal of Organic Chemistry 2011-09-28

Abstract Gene transfer agents (GTAs) are virus-like structures that package and prokaryotic DNA from donor to recipient cells. Here, we describe widespread GTA gene clusters in the highly reduced genomes of bacterial endosymbionts microbial eukaryotes (protists). Homologs capsid portal complexes were initially found be present several alphaproteobacterial diplonemid protists (Rickettsiales Rhodospirillales). Evidence expression was polyA-enriched metatranscriptomes hosts their endosymbionts,...

10.1093/gbe/evac099 article EN cc-by-nc Genome Biology and Evolution 2022-06-23

Multisubstituted furans were readily prepared from (Z)- or (E)-conjugated enynyl acetates with NXS under metal-free conditions at room temperature via the same haloallenyl ketone intermediates. This tandem formation–furan formation reaction sequence was accelerated by electron-donating groups on aromatic rings.

10.1021/jo300251c article EN The Journal of Organic Chemistry 2012-03-23

By using platinum(II) chloride as a Lewis acid catalyst, concise and efficient syntheses of indole carbamates, 1,2-dihydroisoquinoline macrocyclic ureas, phosphoranes have been achieved via tandem Hofmann-type rearrangement 2-alkynylbenzamides 2-alkynylbenzylamides, nucleophilic addition alcohols amines to the isocyanate intermediates, intramolecular aminocyclization thus-formed carbamates ureas 2-alkynyl functions. A variety nucleophiles such alcohols, amines, stable Wittig reagents could...

10.1021/jo101347f article EN The Journal of Organic Chemistry 2010-10-21
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