Login

Aaron Graubert

ORCID: 0000-0001-5539-034X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
A5020100447
Research Areas
  • Genetic Associations and Epidemiology
  • Monoclonal and Polyclonal Antibodies Research
  • vaccines and immunoinformatics approaches
  • Immunotherapy and Immune Responses
  • RNA Research and Splicing
  • Bioinformatics and Genomic Networks
  • RNA modifications and cancer
  • Genomics and Rare Diseases
  • Cancer-related molecular mechanisms research
  • Genomics and Chromatin Dynamics
  • Single-cell and spatial transcriptomics
  • Cancer Genomics and Diagnostics
  • Biomedical Text Mining and Ontologies
  • Genetics, Aging, and Longevity in Model Organisms
  • Genetic Mapping and Diversity in Plants and Animals
  • Genomics and Phylogenetic Studies
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Telomeres, Telomerase, and Senescence
  • Advanced Proteomics Techniques and Applications

Broad Institute
 2021

Washington University in St. Louis
 2016-2020

Stanford University
 2020

James S. McDonnell Foundation
 2016-2018

 The GTEx Consortium atlas of genetic regulatory effects across human tissues
OPENALEX - Publications 
François Aguet Shankara Anand Kristin Ardlie Stacey Gabriel Gad Getz and 95 more Aaron Graubert Kane Hadley Robert E. Handsaker Katherine Huang Seva Kashin Xiao Li Daniel G. MacArthur Samuel R. Meier Jared L. Nedzel Duyen T. Nguyen Ayellet V. Segrè Ellen Todres Brunilda Balliu Alvaro Barbeira Alexis Battle Rodrigo Bonazzola Andrew Brown Christopher Brown Stephane E. Castel Donald F. Conrad Daniel J. Cotter Nancy J. Cox Sayantan Das Olivia M. de Goede Emmanouil T. Dermitzakis Jonah Einson Barbara E. Engelhardt Eleazar Eskin Tiffany Eulalio Nicole M. Ferraro Elise D. Flynn Laure Frésard Eric R. Gamazon Diego Garrido-Martín Nicole R. Gay Michael J. Gloudemans Roderic Guigó Andrew R. Hame Yuan He Paul Hoffman Farhad Hormozdiari Lei Hou Hae Kyung Im Brian Jo Silva Kasela Manolis Kellis Sarah Kim-Hellmuth Alan Kwong Tuuli Lappalainen Xin Li Yanyu Liang Serghei Mangul Pejman Mohammadi Stephen B. Montgomery Manuel Muñoz-Aguirre Daniel Nachun Andrew B. Nobel Meritxell Oliva YoSon Park Yongjin Park Princy Parsana Abhiram Rao Ferrán Reverter John M. Rouhana Chiara Sabatti Ashis Saha Matthew Stephens Barbara E. Stranger Benjamin J. Strober Nicole A. Teran Ana Viñuela Gao Wang Xiaoquan Wen Fred A. Wright Valentin Wucher Yuxin Zou Pedro G. Ferreira Gen Li Marta Melé Esti Yeger‐Lotem Mary E. Barcus Debra Bradbury Tanya Krubit Jeffrey A. McLean Liqun Qi Karna Robinson Nancy Roche Anna Marie Smith Leslie H. Sobin David E. Tabor Anita H. Undale Jason Bridge Lori E. Brigham Barbara A. Foster Bryan M. Gillard

The Genotype-Tissue Expression (GTEx) project dissects how genetic variation affects gene expression and splicing.

10.1126/science.aaz1776 article EN public-domain Science 2020-09-10
 CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer
OPENALEX - Publications 
Malachi Griffith Nicholas C. Spies Kilannin Krysiak Joshua F. McMichael Adam Coffman and 40 more Arpad Danos Benjamin J. Ainscough Cody A. Ramirez Damian Rieke Lynzey Kujan Erica K. Barnell Alex H. Wagner Zachary L. Skidmore Amber Z. Wollam Connor J. Liu Martin Jones Rachel L Bilski Robert Lesurf Yan-Yang Feng Nakul M. Shah Melika Bonakdar Lee Trani Matthew K. Matlock Avinash Ramu Katie M. Campbell Gregory C. Spies Aaron Graubert Karthik Gangavarapu James M. Eldred David E. Larson Jason Walker Benjamin M. Good Chunlei Wu Andrew I. Su Rodrigo Dienstmann Adam A. Margolin David Tamborero Núria López-Bigas Steven J.M. Jones Ron Bose David H. Spencer Lukas D. Wartman Richard K. Wilson Elaine R. Mardis Obi L. Griffith

10.1038/ng.3774 article EN Nature Genetics 2017-01-31
 The impact of sex on gene expression across human tissues
OPENALEX - Publications 
Meritxell Oliva Manuel Muñoz-Aguirre Sarah Kim-Hellmuth Valentin Wucher Ariel DH Gewirtz and 95 more Daniel J. Cotter Princy Parsana Silva Kasela Brunilda Balliu Ana Viñuela Stephane E. Castel Pejman Mohammadi François Aguet Yuxin Zou Ekaterina Khramtsova Andrew D. Skol Diego Garrido-Martín Ferrán Reverter Andrew Brown Patrick Evans Eric R. Gamazon A. J. Payne Rodrigo Bonazzola Alvaro Barbeira Andrew R. Hamel Ángel Martínez-Pérez José Manuel Soria Brandon L. Pierce Matthew Stephens Eleazar Eskin Emmanouil T. Dermitzakis Ayellet V. Segrè Hae Kyung Im Barbara E. Engelhardt Kristin Ardlie Stephen B. Montgomery Alexis Battle Tuuli Lappalainen Roderic Guigó Barbara E. Stranger François Aguet Shankara Anand Kristin Ardlie Stacey Gabriel Gad Getz Aaron Graubert Kane Hadley Robert E. Handsaker Katherine Huang Seva Kashin Xiao Li Daniel G. MacArthur Samuel R. Meier Jared L. Nedzel Duyen T. Nguyen Ayellet V. Segrè Ellen Todres Brunilda Balliu Alvaro Barbeira Alexis Battle Rodrigo Bonazzola Andrew Brown Christopher D. Brown Stephane E. Castel Donald F. Conrad Daniel J. Cotter Nancy J. Cox Sayantan Das Olivia M. de Goede Emmanouil T. Dermitzakis Jonah Einson Barbara E. Engelhardt Eleazar Eskin Tiffany Eulalio Nicole M. Ferraro Elise D. Flynn Laure Frésard Eric R. Gamazon Diego Garrido-Martín Nicole R. Gay Michael J. Gloudemans Roderic Guigó Andrew R. Hame Yuan He Paul Hoffman Farhad Hormozdiari Lei Hou Hae Kyung Im Brian Jo Silva Kasela Manolis Kellis Sarah Kim-Hellmuth Alan Kwong Tuuli Lappalainen Xin Li Yanyu Liang Serghei Mangul Pejman Mohammadi Stephen B. Montgomery Manuel Muñoz-Aguirre

Many complex human phenotypes exhibit sex-differentiated characteristics. However, the molecular mechanisms underlying these differences remain largely unknown. We generated a catalog of sex in gene expression and genetic regulation across 44 tissue sources surveyed by Genotype-Tissue Expression project (GTEx, v8 release). demonstrate that influences levels cellular composition samples body. A total 37% all genes sex-biased at least one tissue. identify cis quantitative trait loci (eQTLs)...

10.1126/science.aba3066 article EN Science 2020-09-10
 Cell type–specific genetic regulation of gene expression across human tissues
OPENALEX - Publications 
Sarah Kim-Hellmuth François Aguet Meritxell Oliva Manuel Muñoz-Aguirre Silva Kasela and 95 more Valentin Wucher Stephane E. Castel Andrew R. Hamel Ana Viñuela Amy L. Roberts Serghei Mangul Xiaoquan Wen Gao Wang Alvaro Barbeira Diego Garrido-Martín Brian B. Nadel Yuxin Zou Rodrigo Bonazzola Jie Quan Andrew Brown Ángel Martínez-Pérez José Manuel Soria Gad Getz Emmanouil T. Dermitzakis Kerrin S. Small Matthew Stephens Hualin Simon Xi Hae Kyung Im Roderic Guigó Ayellet V. Segrè Barbara E. Stranger Kristin Ardlie Tuuli Lappalainen François Aguet Shankara Anand Kristin Ardlie Stacey Gabriel Gad Getz Aaron Graubert Kane Hadley Robert E. Handsaker Katherine Huang Seva Kashin Xiao Li Daniel G. MacArthur Samuel R. Meier Jared L. Nedzel Duyen T. Nguyen Ayellet V. Segrè Ellen Todres Brunilda Balliu Alvaro Barbeira Alexis Battle Rodrigo Bonazzola Andrew Brown Christopher D. Brown Stephane E. Castel Donald F. Conrad Daniel J. Cotter Nancy J. Cox Sayantan Das Olivia M. de Goede Emmanouil T. Dermitzakis Jonah Einson Barbara E. Engelhardt Eleazar Eskin Tiffany Eulalio Nicole M. Ferraro Elise D. Flynn Laure Frésard Eric R. Gamazon Diego Garrido-Martín Nicole R. Gay Michael J. Gloudemans Roderic Guigó Andrew R. Hame Yuan He Paul Hoffman Farhad Hormozdiari Lei Hou Hae Kyung Im Brian Jo Silva Kasela Manolis Kellis Sarah Kim-Hellmuth Alan Kwong Tuuli Lappalainen Xin Li Yanyu Liang Serghei Mangul Pejman Mohammadi Stephen B. Montgomery Manuel Muñoz-Aguirre Daniel Nachun Andrew B. Nobel Meritxell Oliva YoSon Park Yongjin Park Princy Parsana Abhiram Rao

Cell type composition, estimated from bulk tissue, maps the cellular specificity of genetic variants.

10.1126/science.aaz8528 article EN Science 2020-09-10
 Determinants of telomere length across human tissues
OPENALEX - Publications 
Kathryn Demanelis Farzana Jasmine Lin Chen Meytal Chernoff Tong Lin and 95 more Dayana Delgado Chenan Zhang Justin Shinkle Mekala Sabarinathan Hannah Lin Eduardo Ramirez Meritxell Oliva Sarah Kim-Hellmuth Barbara E. Stranger Tsung‐Po Lai Abraham Aviv Kristin Ardlie François Aguet Habibul Ahsan Jennifer A. Doherty Muhammad G. Kibriya Brandon L. Pierce François Aguet Shankara Anand Kristin Ardlie Stacey Gabriel Gad Getz Aaron Graubert Kane Hadley Robert E. Handsaker Katherine Huang Seva Kashin Xiao Li Daniel G. MacArthur Samuel R. Meier Jared L. Nedzel Duyen T. Nguyen Ayellet V. Segrè Ellen Todres Brunilda Balliu Alvaro Barbeira Alexis Battle Rodrigo Bonazzola Andrew Brown Christopher Brown Stephane E. Castel Donald F. Conrad Daniel J. Cotter Nancy J. Cox Sayantan Das Olivia M. de Goede Emmanouil T. Dermitzakis Jonah Einson Barbara E. Engelhardt Eleazar Eskin Tiffany Eulalio Nicole M. Ferraro Elise D. Flynn Laure Frésard Eric R. Gamazon Diego Garrido-Martín Nicole R. Gay Michael J. Gloudemans Roderic Guigó Andrew R. Hame Yuan He Paul Hoffman Farhad Hormozdiari Lei Hou Hae Kyung Im Brian Jo Silva Kasela Manolis Kellis Sarah Kim-Hellmuth Alan Kwong Tuuli Lappalainen Xin Li Yanyu Liang Serghei Mangul Pejman Mohammadi Stephen B. Montgomery Manuel Muñoz-Aguirre Daniel Nachun Andrew B. Nobel Meritxell Oliva YoSon Park Yongjin Park Princy Parsana Abhiram Rao Ferrán Reverter John M. Rouhana Chiara Sabatti Ashis Saha Matthew Stephens Barbara E. Stranger Benjamin J. Strober Nicole A. Teran Ana Viñuela Gao Wang Xiaoquan Wen

Telomere length within an individual varies in a correlated manner across most tissues.

10.1126/science.aaz6876 article EN Science 2020-09-10
 A Quantitative Proteome Map of the Human Body
OPENALEX - Publications 
Lihua Jiang Meng Wang Shin Lin Ruiqi Jian Xiao Li and 95 more Joanne Chan Guanlan Dong Huaying Fang Aaron Robinson M Snyder François Aguet Shankara Anand Kristin Ardlie Stacey Gabriel Gad Getz Aaron Graubert Kane Hadley Robert E. Handsaker Katherine Huang Seva Kashin Daniel G. MacArthur Samuel R. Meier Jared L. Nedzel Duyen Y. Nguyen Ayellet V. Segrè Ellen Todres Brunilda Balliu Alvaro Barbeira Alexis Battle Rodrigo Bonazzola Andrew Brown Christopher Brown Stephane E. Castel Don Conrad Daniel J. Cotter Nancy J. Cox Sayantan Das Olivia M. de Goede Emmanouil T. Dermitzakis Barbara E. Engelhardt Eleazar Eskin Tiffany Eulalio Nicole M. Ferraro Elise D. Flynn Laure Frésard Eric R. Gamazon Diego Garrido-Martín Nicole R. Gay Roderic Guigó Andrew R. Hamel Yuan He Paul Hoffman Farhad Hormozdiari Lei Hou Hae Kyung Im Brian Jo Silva Kasela Manolis Kellis Sarah Kim-Hellmuth Alan Kwong Tuuli Lappalainen Xin Li Yanyu Liang Serghei Mangul Pejman Mohammadi Stephen B. Montgomery Manuel Muñoz-Aguirre Daniel Nachun Andrew B. Nobel Meritxell Oliva YoSon Park Yongjin Park Princy Parsana Ferrán Reverter John M. Rouhana Chiara Sabatti Ashis Saha Andrew D. Skol Matthew Stephens Barbara E. Stranger Benjamin J. Strober Nicole A. Teran Ana Viñuela Gao Wang Xiaoquan Wen Fred A. Wright Valentin Wucher Yuxin Zou Pedro G. Ferreira Gen Li Marta Melé Esti Yeger‐Lotem Mary E. Barcus Debra Bradbury Tanya Krubit Jeffrey A. McLean Liqun Qi Karna Robinson Nancy Roche Anna Marie Smith

10.1016/j.cell.2020.08.036 article EN publisher-specific-oa Cell 2020-09-10
 pVACtools: A Computational Toolkit to Identify and Visualize Cancer Neoantigens
OPENALEX - Publications 
Jasreet Hundal Susanna Kiwala Joshua F. McMichael Christopher A. Miller Huiming Xia and 13 more Alexander T. Wollam Connor J. Liu Sidi Zhao Yang-Yang Feng Aaron Graubert Amber Z. Wollam Jonas Neichin Megan N. Thomas Jason Walker William E. Gillanders Elaine R. Mardis Obi L. Griffith Malachi Griffith

Identification of neoantigens is a critical step in predicting response to checkpoint blockade therapy and design personalized cancer vaccines. This cross-disciplinary challenge, involving genomics, proteomics, immunology, computational approaches. We have built framework called pVACtools that, when paired with well-established genomics pipeline, produces an end-to-end solution for neoantigen characterization. supports identification altered peptides from different mechanisms, including...

10.1158/2326-6066.cir-19-0401 article EN Cancer Immunology Research 2020-01-06
 Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease
OPENALEX - Publications 
Olivia M. de Goede Daniel Nachun Nicole M. Ferraro Michael J. Gloudemans Abhiram Rao and 95 more Craig Smail Tiffany Eulalio François Aguet Bernard Ng Jishu Xu Alvaro Barbeira Stephane E. Castel Sarah Kim-Hellmuth YoSon Park Alexandra J. Scott Benjamin J. Strober Christopher D. Brown Xiaoquan Wen Ira M. Hall Alexis Battle Tuuli Lappalainen Hae Kyung Im Kristin Ardlie Sara Mostafavi Thomas Quertermous Karla Kirkegaard Stephen B. Montgomery Shankara Anand Stacey Gabriel Gad Getz Aaron Graubert Kane Hadley Robert E. Handsaker Katherine Huang Xiao Li Daniel G. MacArthur Samuel R. Meier Jared L. Nedzel Duyen T. Nguyen Ayellet V. Segrè Ellen Todres Brunilda Balliu Rodrigo Bonazzola Andrew Brown Donald F. Conrad Daniel J. Cotter Nancy J. Cox Sayantan Das Emmanouil T. Dermitzakis Jonah Einson Barbara E. Engelhardt Eleazar Eskin Elise D. Flynn Laure Frésard Eric R. Gamazon Diego Garrido-Martín Nicole R. Gay Roderic Guigó Andrew R. Hamel Yuan He Paul Hoffman Farhad Hormozdiari Lei Hou Brian Jo Silva Kasela Seva Kashin Manolis Kellis Alan Kwong Xin Li Yanyu Liang Serghei Mangul Pejman Mohammadi Manuel Muñoz-Aguirre Andrew B. Nobel Meritxell Oliva Yong‐Jin Park Princy Parsana Ferrán Reverter John M. Rouhana Chiara Sabatti Ashis Saha Matthew Stephens Barbara E. Stranger Nicole A. Teran Ana Viñuela Gao Wang Fred A. Wright Valentin Wucher Yuxin Zou Pedro G. Ferreira Gen Li Marta Melé Esti Yeger‐Lotem Debra Bradbury Tanya Krubit Jeffrey A. McLean Liqun Qi Karna Robinson Nancy Roche Anna M. Smith

10.1016/j.cell.2021.03.050 article EN publisher-specific-oa Cell 2021-04-16
 Transcriptomic signatures across human tissues identify functional rare genetic variation
OPENALEX - Publications 
Nicole M. Ferraro Benjamin J. Strober Jonah Einson Nathan S. Abell François Aguet and 95 more Alvaro Barbeira Margot Brandt Maja Bućan Stephane E. Castel Joe R. Davis Emily Greenwald Gaelen T. Hess Austin T. Hilliard Rachel L. Kember Bence Kotis YoSon Park Gina M. Peloso Shweta Ramdas Alexandra J. Scott Craig Smail Emily K. Tsang Seyedeh M. Zekavat Marcello Ziosi Aradhana Kristin Ardlie Themistocles L. Assimes Michael C. Bassik Christopher D. Brown Adolfo Correa Ira M. Hall Hae Kyung Im Xin Li Pradeep Natarajan Tuuli Lappalainen Pejman Mohammadi Stephen B. Montgomery Alexis Battle François Aguet Shankara Anand Kristin Ardlie Stacey Gabriel Gad Getz Aaron Graubert Kane Hadley Robert E. Handsaker Katherine Huang Seva Kashin Xiao Li Daniel G. MacArthur Samuel R. Meier Jared L. Nedzel Duyen T. Nguyen Ayellet V. Segrè Ellen Todres Brunilda Balliu Alvaro Barbeira Alexis Battle Rodrigo Bonazzola Andrew Brown Christopher D. Brown Stephane E. Castel Donald F. Conrad Daniel J. Cotter Nancy J. Cox Sayantan Das Olivia M. de Goede Emmanouil T. Dermitzakis Jonah Einson Barbara E. Engelhardt Eleazar Eskin Tiffany Eulalio Nicole M. Ferraro Elise D. Flynn Laure Frésard Eric R. Gamazon Diego Garrido-Martín Nicole R. Gay Michael J. Gloudemans Roderic Guigó Andrew R. Hame Yuan He Paul Hoffman Farhad Hormozdiari Lei Hou Hae Kyung Im Brian Jo Silva Kasela Manolis Kellis Sarah Kim-Hellmuth Alan Kwong Tuuli Lappalainen Xin Li Yanyu Liang Serghei Mangul Pejman Mohammadi Stephen B. Montgomery Manuel Muñoz-Aguirre Daniel Nachun Andrew B. Nobel Meritxell Oliva

Outliers in the human transcriptome reveal functional effects of rare genetic variants.

10.1126/science.aaz5900 article EN Science 2020-09-10
 A vast resource of allelic expression data spanning human tissues
OPENALEX - Publications 
Stephane E. Castel François Aguet Pejman Mohammadi François Aguet Shankara Anand and 95 more Kristin Ardlie Stacey Gabriel Gad Getz Aaron Graubert Kane Hadley Robert E. Handsaker Katherine Huang Seva Kashin Xiao Li Daniel G. MacArthur Samuel R. Meier Jared L. Nedzel Duyen T. Nguyen Ayellet V. Segrè Ellen Todres François Aguet Shankara Anand Kristin Ardlie Brunilda Balliu Alvaro Barbeira Alexis Battle Rodrigo Bonazzola Andrew Brown Christopher D. Brown Stephane E. Castel Donald F. Conrad Daniel J. Cotter Nancy J. Cox Sayantan Das Olivia M. de Goede Emmanouil T. Dermitzakis Jonah Einson Barbara E. Engelhardt Eleazar Eskin Tiffany Eulalio Nicole M. Ferraro Elise D. Flynn Laure Frésard Eric R. Gamazon Diego Garrido-Martín Nicole R. Gay Gad Getz Michael J. Gloudemans Aaron Graubert Roderic Guigó Kane Hadley Andrew R. Hame Robert E. Handsaker Yuan He Paul Hoffman Farhad Hormozdiari Lei Hou Katherine Huang Hae Kyung Im Brian Jo Silva Kasela Seva Kashin Manolis Kellis Sarah Kim-Hellmuth Alan Kwong Tuuli Lappalainen Xiao Li Xin Li Yanyu Liang Daniel G. MacArthur Serghei Mangul Samuel R. Meier Pejman Mohammadi Stephen B. Montgomery Manuel Muñoz-Aguirre Daniel Nachun Jared L. Nedzel Duyen T. Nguyen Andrew B. Nobel Meritxell Oliva Yo Son Park Yong‐Jin Park Princy Parsana Abhiram Rao Ferrán Reverter John M. Rouhana Chiara Sabatti Ashis Saha Ayellet V. Segrè Andrew D. Skol Matthew Stephens Barbara E. Stranger Benjamin J. Strober Nicole A. Teran Ellen Todres Ana Viñuela Gao Wang Xiaoquan Wen Fred A. Wright Valentin Wucher

Abstract Allele expression (AE) analysis robustly measures cis -regulatory effects. Here, we present and demonstrate the utility of a vast AE resource generated from GTEx v8 release, containing 15,253 samples spanning 54 human tissues for total 431 million measurements at SNP level 153 haplotype level. In addition, develop an extension our tool phASER that allows effect sizes variants to be estimated using haplotype-level data. This is largest date, are able make data publicly available. We...

10.1186/s13059-020-02122-z article EN cc-by Genome biology 2020-09-10
 RNA-SeQC 2: efficient RNA-seq quality control and quantification for large cohorts
OPENALEX - Publications 
Aaron Graubert François Aguet Arvind Ravi Kristin Ardlie Gad Getz

Post-sequencing quality control is a crucial component of RNA sequencing (RNA-seq) data generation and analysis, as sample can be affected by storage, extraction protocols. RNA-seq increasingly applied to cohorts ranging from hundreds tens thousands samples in size, but existing tools do not readily scale these sizes, were designed for wide range types qualities. Here, we describe RNA-SeQC 2, an efficient reimplementation (DeLuca et al., 2012) that adds multiple metrics characterize across...

10.1093/bioinformatics/btab135 article EN Bioinformatics 2021-02-27
 pVACtools: a computational toolkit to identify and visualize cancer neoantigens
OPENALEX - Publications 
Jasreet Hundal Susanna Kiwala Joshua F. McMichael Christopher A. Miller Alexander T. Wollam and 13 more Huiming Xia Connor J. Liu Sidi Zhao Yang-Yang Feng Aaron Graubert Amber Z. Wollam Jonas Neichin Megan N. Thomas Jason Walker William E. Gillanders Elaine R. Mardis Obi L. Griffith Malachi Griffith

Abstract Identification of neoantigens is a critical step in predicting response to checkpoint blockade therapy and design personalized cancer vaccines. We have developed an silico sequence analysis toolkit - pVACtools, facilitate comprehensive neoantigen characterization. pVACtools supports modular workflow consisting tools for prediction from somatic alterations (pVACseq pVACfuse), prioritization selection using graphical web-based interface (pVACviz) DNA vector-based vaccines (pVACvector)...

10.1101/501817 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2018-12-19
 CIViC: A knowledgebase for expert-crowdsourcing the clinical interpretation of variants in cancer
OPENALEX - Publications 
Malachi Griffith Nicholas C. Spies Kilannin Krysiak Adam Coffman Joshua F. McMichael and 35 more Benjamin J. Ainscough Damian Rieke Arpad Danos Lynzey Kujan Cody A. Ramirez Alex H. Wagner Zachary L. Skidmore Connor J. Liu Martin Jones Rachel L Bilski Robert Lesurf Erica K. Barnell Nakul M. Shah Melika Bonakdar Lee Trani Matthew K. Matlock Avinash Ramu Katie M. Campbell Gregory C. Spies Aaron Graubert Karthik Gangavarapu James M. Eldred David E. Larson Jason Walker Benjamin M. Good Chunlei Wu Andrew I. Su Rodrigo Dienstmann Steven J.M. Jones Ron Bose David H. Spencer Lukas D. Wartman Richard K. Wilson Elaine R. Mardis Obi L. Griffith

Abstract CIViC is an expert crowdsourced knowledgebase for Clinical Interpretation of Variants in Cancer ( www.civicdb.org ) describing the therapeutic, prognostic, and diagnostic relevance inherited somatic variants all types. committed to open source code, access content, public application programming interfaces (APIs), provenance supporting evidence allow transparent creation current accurate variant interpretations use cancer precision medicine.

10.1101/072892 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2016-09-01
 griffithlab/pVACtools: 2.0.0
OPENALEX - Publications 
Susanna Kiwala Aaron Graubert mrjosh Alexander Wollam Malachi Griffith and 12 more amberzw jhundal Thomas B. Mooney Jason Walker Joshua F. McMichael T Pavel Chris Miller Jonas Neichin Feng Yangyang Obi L. Griffith Ryan S. King William McLaren

10.5281/zenodo.4520122 article 2021-02-08
 26. pVACtools: Computational selection and visualization of neoantigens for personalized cancer vaccine design
OPENALEX - Publications 
Susanna Kiwala Jasreet Hundal Joshua F. McMichael Yang-Yang Feng Christopher A. Miller and 9 more Aaron Graubert Amber Z. Wollam Connor Liu Jonas Neichin Megan N. Thomas Jason Walker Elaine R. Mardis Obi L. Griffith Malachi Griffith

10.1016/j.cancergen.2018.04.087 article EN Cancer Genetics 2018-07-10
 griffithlab/pVACtools: 1.5.0
OPENALEX - Publications 
Susanna Kiwala Aaron Graubert mrjosh atwollam Malachi Griffith and 10 more amberzw jhundal Thomas B. Mooney Joshua F. McMichael Jason Walker Chris Miller Jonas Neichin Obi L. Griffith William McLaren Ryan S. King

10.5281/zenodo.3362564 article 2019-08-07
Coming Soon ...