A5019094580- Diabetes and associated disorders
- Diabetes Management and Research
- Urological Disorders and Treatments
- Sexual Differentiation and Disorders
- Child Nutrition and Water Access
- Pelvic floor disorders treatments
- Adolescent and Pediatric Healthcare
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Child and Adolescent Health
- Anorectal Disease Treatments and Outcomes
- Blood groups and transfusion
- COVID-19 Clinical Research Studies
- Pharmaceutical studies and practices
- Diverticular Disease and Complications
- Pancreatitis Pathology and Treatment
- Diabetes Treatment and Management
- Urologic and reproductive health conditions
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pediatric Pain Management Techniques
- Global Maternal and Child Health
- Child Nutrition and Feeding Issues
- Malaria Research and Control
- Hemoglobinopathies and Related Disorders
- Pleural and Pulmonary Diseases
- Genital Health and Disease
Kwame Nkrumah University of Science and Technology
2017-2025
Komfo Anokye Teaching Hospital
2014-2023
Institute of Child Health
2019-2022
Kwame Nkrumah University
2017-2022
Diabetes Australia
2017
Creative Research Enterprises (United States)
2017
Nurses' Training College, Ho
2017
University College London
2011-2017
Royal London Hospital
2017
University College Hospital
2011-2016
Real-world data on vaccine-elicited neutralising antibody responses for two-dose AZD1222 in African populations are limited. We assessed baseline SARS-CoV-2 seroprevalence and levels of protective neutralizing antibodies prior to vaccination rollout using binding analysis coupled with pseudotyped virus neutralisation assays two cohorts from West Africa: Nigerian healthcare workers (n = 140) a Ghanaian community cohort 527) pre post vaccination. found 44 28% pre-vaccination participants...
ABSTRACT Background and Aims Due to the reduction in immunity caused by auto‐splenectomy consequent opsonic antibody shortage, patients with SCD are more susceptible encapsulated organism infections, especially asymptomatic urinary tract infection (ASM‐UTI). This study investigated prevalence of ASM‐UTI compared urine hematology parameters among Ghana their healthy counterparts. Methods In this study, 104 participants (cases) 80 non‐SCD (HbAA) controls were recruited. Participants'...
Early initiation of breastfeeding (EIBF), within first hour after birth, is known to have major benefits for both the mother and newborn. EIBF rates, however, tends vary between countries. This study set out determine prevalence at Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana, evaluate determinants time breastfeeding.A cross-sectional was conducted KATH postnatal wards August October 2014. Three hundred eighty-two mothers delivering were recruited data on breastfeeding, antenatal,...
Data on normative clitoral sizes in newborns is relatively sparse and racial/ethnic differences have also been reported. This study was performed to establish norms for size term Ghanaian female newborns.This a cross-sectional of all apparently well full-term postnatal age < 48 h birth weight between 2.5 4.0 kg delivered at Komfo Anokye Teaching Hospital May September, 2014. Anthropometric genital parameters were documented subjects as parental socio-demographic indices.In 612 newborn...
To determine the clinical features of diabetes in children and adolescents Ghana.
Genital measurements are a useful adjunct in the early detection of various endocrine conditions including hypopituitarism and disorders sexual differentiation. Standards for genital sizes have been published but racial/ethnic differences exist. This study was done to establish norms term Ghanaian male newborns.This cross-sectional all apparently well full-term newborns postnatal age < 48 h birth weight between 2.5 4.0 kg delivered at Komfo Anokye Teaching Hospital within period....
Objective The incidence of disorders sexual development (DSD) is unknown in sub-Saharan Africa. We describe the characteristics and DSD a cohort infants born Ghana. Design Trained research assistants performed systematic genital examination at birth. All with suspected abnormal genitalia were further examined by paediatric endocrinologist. Setting Komfo Anokye Teaching Hospital, Kumasi, Patients Consecutive single centre over 1-year period (May 2014 to April 2015). Main outcome measures...
Background: Malnutrition is a significant public health problem and major cause of morbidity mortality in children.
 Aims: To assess knowledge socioeconomic status caregivers children under 5 years with malnutrition at district hospital Ghana.
 Methods: Case Report forms were used to gather data cross-sectional study which was carried out among 189 their aged from zero fifty-nine months the Out-Patient Department clinic.
 Results: Most (80.95%) had marasmus. Sixty-two point...
Dysglycaemia (hyper- or hypoglycaemia) in critically ill children has been associated with poor outcome. We compared the clinical outcomes admitted to Pediatric Emergency Unit (PEU) at Komfo Anokye Teaching Hospital (KATH) for acute medical conditions and presenting euglycaemia dysglycaemia. This is a prospective case matching cohort study. Eight hundred subjects aged between 3 144 months were screened out of whom 430 (215 215 dysglycaemia) enrolled. The median age was 24 (range: 3–144...
Over-diagnosis of malaria among African children results in mismanagement non-malaria infections. Limited laboratory capacity makes it difficult to implement policies that recommend pre-treatment confirmation infections so a new approach with package for on-the-spot management fevers was evaluated. Febrile presenting outpatient clinic were randomized receive either 'test-treat' (history clinical examination; point-of-care tests; choice artesunate-amodiaquine, co-amoxiclav and/or paracetamol)...
Faecal incontinence (FI) is distressing, significantly reduces quality of life (QoL) and has few pharmacological treatments. The α1-adrenoceptor agonist NRL001 (1R,2S-methoxamine hydrochloride) improves anal sphincter tone. efficacy was evaluated by changes in Wexner scores at week 4 vs. baseline NRL001-treated patients compared with placebo. Impact on QoL safety were also assessed. Four hundred sixty-six received (5, 7.5 or 10 mg) placebo as suppository, once daily over 8 weeks. score,...
<b><i>Background:</i></b> Anogenital distance (AGD) is a simple noninvasive measure of foetal androgen exposure. This study was done to generate normative data on AGD in Ghanaian newborns. <b><i>Methods:</i></b> measured 644 male and 612 female term newborns; including the between anterior base penis centre anus, posterior scrotum anus (ASD) males from fourchette (AF) clitoris females. Other anthropometric parental socio-demographic indices...
Spinal muscular atrophy (SMA) is an autosomal recessive inherited motor neuron disease characterized by progressive muscle weakness due to degeneration and loss of the anterior horn cells in spinal cord brain stem nuclei from foetal life through infancy childhood. SMA prevalent Ghanaian children, though not widely reported. Cases are likely missed or misdiagnosed lack expertise investigations. Newborn screening currently available Ghana. The management remains supportive as newly approved...
To assess the knowledge and practice of malaria prevention among caregivers children admitted to a teaching hospital in Ghana. A descriptive cross-sectional survey was conducted on who were hospitalized at paediatric wards Komfo Anokye Teaching Hospital from March 2009 June 2009. Data analysed using StataTM version 8.2. Nearly all (97.1%) had heard malaria. Of this proportion, 89.7% knew mosquito bite as cause The proportion able recognise signs symptoms 87.6% (for fever), 47.1% vomiting)...
<b><i>Background:</i></b> Access to essential medicines in pediatric endocrinology and diabetes is limited resource-limited countries. The World Health Organization (WHO) maintains two non-binding lists of (EMLs) which are often used as a template for developing national EMLs. <b><i>Methods:</i></b> We compared previously published master list with the WHO EMLs countries within African region. To better understand actual access by patients, we...
Lower limb amputation is a debilitating complication of diabetes which rare in children and adolescents with type 1 diabetes. Most amputations are rather due to other causes such as trauma congenital anomalies. Lack access supervised coordinated medical care for Africa make them susceptible complications Early detection soft tissue infections the leg aggressive wound management coupled tight glycaemic control important avert lower among
Misdiagnosis of diabetic ketoacidosis (DKA) among children and adolescents with diabetes is often misdiagnosed in clinical practice Ghana, it occurs at primary, secondary tertiary care settings all grades health practitioners.This because DKA mimics many other disorders such as infections, surgical obstetric emergencies these conditions are more frequently seen hospitals Ghana than diabetes.It is, therefore, paramount that every child or adolescent presenting to a facility any suspected...
Objectives: This study aimed to determine the spectrum of diseases admitted neonatal unit a Teaching Hospital in Ghana. Methods: Prospective cross-sectional descriptive done on Mother Baby Unit (MBU), ward, Komfo Anokye Hospital, Kumasi. Data were collected daily between 8 hrs and 20 GMT. Information was obtained from both clinical team mothers neonates. included age, weight, sex, place delivery diagnosis including congenital anomalies syndromes. Analysis using Stata version 12. Ethical...
Wrongly diagnosing diabetic ketoacidosis (DKA) among children and adolescents with diabetes, by doctors other health workers, is often seen in clinical practice Ghana although not much reported the literature. It occurs at primary, secondary tertiary care settings all grades of practitioners. This due to low level awareness practitioners community. Besides, features DKA mimic many infections which are more frequently hospitals than diabetes. is, therefore, paramount that every child or...
<title>Abstract</title> Background: Due to the reduction in immunity caused by auto-splenectomy and consequent opsonic antibody shortage, patients with SCD are more susceptible encapsulated organism infections, especially asymptomatic urinary tract infection (ASM-UTI). This study investigated prevalence of compared urine haematology parameters among Ghana their healthy counterparts. Methods: In this study, 104 participants 80 non-SCD subjects were recruited. Participants' information was...
Differences in sex development (DSD) are congenital conditions which the of chromosomal, gonadal, or anatomical is atypical. Ovotesticular DSD rarest variant where both ovarian and testicular tissues co-exist an individual. Ambiguous genitalia may be a glaring indicator DSD, but multiple genital anomalies should also raise suspicion DSD. This case report 15-year-6-month-old boy who presented during infancy with requiring surgery. The diagnosis ovotesticular was missed until later adolescence...