A5034092526- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Neuroscience and Neuropharmacology Research
- Electroconvulsive Therapy Studies
- Migraine and Headache Studies
- Treatment of Major Depression
- Takotsubo Cardiomyopathy and Associated Phenomena
- Neonatal and fetal brain pathology
- Trigeminal Neuralgia and Treatments
- Cerebrospinal fluid and hydrocephalus
- EEG and Brain-Computer Interfaces
- Ophthalmology and Eye Disorders
- Glioma Diagnosis and Treatment
- Parasitic infections in humans and animals
- Infectious Encephalopathies and Encephalitis
- Sympathectomy and Hyperhidrosis Treatments
- Mosquito-borne diseases and control
- Genetic Neurodegenerative Diseases
- Hemoglobinopathies and Related Disorders
- Neurological Complications and Syndromes
- Viral Infections and Immunology Research
- Sexual function and dysfunction studies
- Cerebral Venous Sinus Thrombosis
- Genetic and Kidney Cyst Diseases
- Neurological disorders and treatments
M. P. Shah Medical College
2015-2022
Institute of Medical Sciences and Sum Hospital
2018-2021
Creative Commons
2021
Institute of Medical Sciences
2020
Sree Chitra Thirunal Institute for Medical Sciences and Technology
2009-2019
Stanley Medical College
2018
Narayana Health
2018
Central India Institute of Medical Sciences
2018
University College London
2013-2014
National Hospital for Neurology and Neurosurgery
2013-2014
Abstract Objective 18F‐Fluorodeoxyglucose positron emission tomography (FDG‐PET) is widely used in presurgical assessment patients with drug‐resistant focal epilepsy (DRE) if magnetic resonance imaging (MRI) and scalp electroencephalography (EEG) do not localize the seizure onset zone or are discordant. Methods In this multicenter, retrospective observational cohort study, we included consecutive DRE who had undergone FDG‐PET as part of their workup. We assessed utility FDG‐PET, which was...
To investigate the feasibility of antiepileptic drug (AED) withdrawal following anterior temporal lobectomy (ATL) and to identify predictors post seizure recurrence.We prospectively studied outcome 310 consecutive patients, who were followed for a minimum 5 years ATL medically refractory mesial lobe epilepsy. In seizure-free we started AED tapering at 3 months in patients on duotherapy/polytherapy 1 year after those monotherapy. We used Kaplan-Meier survival curves estimate probability...
Summary Purpose In contrast to the well‐recognized association between acute symptomatic seizures and neurocysticercosis, antiepileptic drug ( AED )–resistant epilepsy calcified neurocysticercosis lesions CNL s) is poorly understood. We studied ‐resistant s, including feasibility outcome of resective surgery. Methods From prospective database maintained at our center, we reviewed data all patients with who underwent presurgical evaluation from January 2001 July 2010 had on imaging. used...
To identify the rate of successful antiepileptic drug (AED) withdrawal after resective surgery and predictors postwithdrawal seizure recurrence in patients with extratemporal epilepsy.We retrospectively analyzed postoperative AED profile 106 consecutive who had completed 2 or more years resections involving frontal, parietal, occipital lobes for AED-resistant epilepsy. potential recurrence, we compared attributes recurred nonrecurred groups by univariate multivariate analyses.We attempted 94...
Summary In areas where cysticercosis is endemic, calcified neurocysticercosis lesion(s) (CNL) and hippocampal sclerosis (HS) commonly coexist in patients with localization‐related epilepsies. To understand the pathogenesis of HS associated CNL, we compared characteristics three groups antiepileptic drug–resistant epilepsies: CNL HS, without (CNL alone), (HS alone). comparison to alone, those had more frequently located ipsilateral temporal lobe. Those a lower incidence febrile seizures,...
Summary Lacosamide, a recently introduced antiepileptic drug, acts by enhancing the slow inactivation of voltage‐dependent sodium channels. Cardiac conduction disturbances, namely atrial fibrillation and atrioventricular block, have been reported in patients with epilepsy. We report patient drug‐resistant focal epilepsy who developed asymptomatic sinus node dysfunction following lacosamide use, which resolved on stopping lacosamide. This is first associated therapy.
Objective To see the interrelation between chronic tension‐type headache (CTTH) and serum vitamin D levels. Background Several studies have suggested an association pain deficiency. Anecdotal evidence suggests that deficiency may be associated with migraine. Methods This case‐control study was carried out to examine CTTH 25‐hydroxy (25(OH) D) One hundred consecutive adult (>18 years) patients 100 matched healthy controls were enrolled. Results The 25(OH) levels significantly lower in than...
Purpose: To design a non–patient-specific system to detect the electrical onset of seizures in patients with temporal lobe epilepsy. Methods: We used EEG data from 29 18 epilepsy who underwent multiday video-scalp monitoring as part their presurgical evaluations. segmented each set into preictal and ictal phases, identified spectral entropy, energy, signal energy useful features for discriminating normal seizure conditions. The performance five different classifiers was analyzed using these...
To assess the value of postoperative EEG in predicting seizure outcome and recurrence following antiepileptic drug (AED) withdrawal patients with mesial temporal lobe epilepsy hippocampal sclerosis (MTLE-HS).We studied 262 consecutive MTLE-HS serial EEGs at 3 months, 1, 2, years after anterior lobectomy (ATL), considered presence interictal epileptiform discharges (IED) as abnormal. We attempted AED all seizure-free patients. defined favorable freedom from seizures/auras during entire...
Objective To undertake the epidemiological evaluation of patients presenting with side‐locked headache and facial pain in a tertiary neurology outpatient clinic. Background Side‐locked unilateral include large number primary secondary headaches cranial neuropathies. A diagnostic approach for strictly is important as many these disorders respond to highly selective drug. Epidemiological data may guide us formulate proper such patients. However, literature sparse on pain. Methods We...
To study the long-term outcome following seizure recurrence on antiepileptic drug (AED) withdrawal after anterior temporal lobectomy for mesial lobe epilepsy.We retrospectively studied AED profile of patients who had a minimum 5 years postoperative follow-up epilepsy. Only those with hippocampal sclerosis or normal MRI were included. was initiated at 3 months in ≥2 drugs and 1 year single drug.Three hundred eighty-four median 12 (range, 7-17 years) Of them, 316 (82.3%) seizure-free during...
Objective: To study the long-term effectiveness of Theta Burst Stimulation (TBS) or Functional Electrical (FES) combined with Physical therapy (PT) as compared to PT alone for improving arm functions in patients acute stroke. Design: Single blind randomized controlled trial. Setting: Outpatient clinics and inpatient wards at tertiary care neurology center. Subjects: Adult middle cerebral artery territory ischemic Interventions: 60 were into three groups 20 each: TBS+PT; FES+PT; alone. TBS...