- Berberine and alkaloids research
- Chemical synthesis and alkaloids
- Synthesis and Biological Activity
- Neurological Disease Mechanisms and Treatments
- Natural product bioactivities and synthesis
- Adipose Tissue and Metabolism
- Traditional Chinese Medicine Studies
- Ginger and Zingiberaceae research
- Traditional Chinese Medicine Analysis
- Gut microbiota and health
- Traditional and Medicinal Uses of Annonaceae
- Plant chemical constituents analysis
- Phytochemistry and Biological Activities
- Peroxisome Proliferator-Activated Receptors
- Plant-based Medicinal Research
- Adipokines, Inflammation, and Metabolic Diseases
- Folate and B Vitamins Research
- Plant-derived Lignans Synthesis and Bioactivity
- Mangiferin and Mango Extracts
- Metabolism and Genetic Disorders
- Metabolomics and Mass Spectrometry Studies
- Alkaloids: synthesis and pharmacology
- Circular RNAs in diseases
- Phytochemicals and Antioxidant Activities
- Iron Metabolism and Disorders
Hunan University of Traditional Chinese Medicine
2009-2023
Xuzhou Medical College
2022
Chinese Academy of Sciences
2015
Shanghai Institute of Materia Medica
2015
China Pharmaceutical University
2009
Traditionally, the quality evaluation of Chrysanthemum morifolium (CM) cv. (Juhua) attributes its habitats and processing methods, however, this strategy neglecting bioactive ingredients usually results in deviation evaluation. This study aims to explore marker (Q-marker) based on spectrum-effect relationship control CMs. The chromatographic fingerprint 30 flower head samples CMs from five different including Hang-baiju, Gongju, Huaiju, Taiju Boju were constructed by high performance liquid...
Mulberry leaves exhibit anti-lipogenic and lipid-lowering effects. However, the lipid biomarkers underlying mechanisms for improvement of action mulberry on obesity metabolism disorders have not been sufficiently investigated yet. Herein, biochemical analysis combined with metabolomics targeting serum mediators (oxylipins) were used to explore efficacy leaf water extract (MLWE) in high-fat high-sucrose diet (HFHSD)-fed mice. Our results showed that MLWE supplementation only decreased body...
To study the chemical constituents from Zanthoxylum simulans and their anti-inflammatory activity. The of Z. were isolated purified using various column chromatographies. Their structures elucidated extensive spectroscopic methods. compounds assayed inhibitory activity against NO production in LPS stimulated RAW 264.7 cells. Four obtained ethanol extract determined to be isozanthpodocarpin B(1), kobusin (2), (+)-fargesin (3), epieudesmin (4). Compound 1 exhibited effect with IC50 value 14.49...
The objective of this study was to explore the medicinal properties herbal medicines that can interfere with copper death pathway.The Human Gene Database, Chemical Interactions in Comparative Toxicogenomics Encyclopedia Traditional Chinese Medicine, China Medical Information Platform, and Cytoscape software were used find target chemicals targets, as well containing these their four natures five flavors (basic medicines).27 death-related targets finally retrieved, 2143 could them, including...
The study was conducted by searching the literature related to regulation of necroptosis with Chinese medicine from January 1, 2005 December 31, 2021 in CNKI, VIP, Wanfang, Web Science(WoS), and PubMed. obtained were imported into NoteExpress for eliminating duplicates screening, final included articles Excel plot publication trend. core authors identified according Price's law, VOSviewer 1.6.17 used draw a collaborative view sort high-frequency keywords. Then CiteSpace 5.8.R3 employed...
We employed bibliometrics to comprehensively study the hotspots and frontiers of gut microbiota research involving traditional Chinese medicine(TCM), aiming provide new ideas for subsequent in this field. The studies with TCM published from January 1, 2002 December 31, 2021 were retrieved CNKI, Wanfang, VIP Web Science(WoS). After data screening cleaning, CiteSpace 5.8.R3 was used visualize analyze authors, journals, keywords. A total 1 119 articles 815 English included study. period...
Objective To investigate the mechanisms of Chinese traditional medicine mixture protection vascular endothelial cell from apoptosis in cerebral ischemia-reperfusion injury. Methods Healthy, clean SD rats were randomly divided into 4 groups: Sham opera-tion group (SOG), ischemia reperfusion injury (IRG), preconditioning (IPG) and tradi-tional (CPG). Furthermore, IRG, IPG NPC sub-groups: 1 d, 7d, 14d, 21d subgroup, according to different time point since took place. And CPG, Naotai formula...