A5023156336- Alzheimer's disease research and treatments
- Cancer Cells and Metastasis
- Cholinesterase and Neurodegenerative Diseases
- Neuroinflammation and Neurodegeneration Mechanisms
- Berberine and alkaloids research
- Ginger and Zingiberaceae research
- Epigenetics and DNA Methylation
- Nanoparticles: synthesis and applications
- 3D Printing in Biomedical Research
- Tryptophan and brain disorders
- Skin Protection and Aging
- Bioactive natural compounds
- Silicone and Siloxane Chemistry
- Nanoparticle-Based Drug Delivery
- Histone Deacetylase Inhibitors Research
- Phytochemicals and Medicinal Plants
- Computational Drug Discovery Methods
- Animal Virus Infections Studies
- SARS-CoV-2 and COVID-19 Research
- Wound Healing and Treatments
- IL-33, ST2, and ILC Pathways
- Genetics and Neurodevelopmental Disorders
- COVID-19 Clinical Research Studies
- Dendrimers and Hyperbranched Polymers
- Natural Antidiabetic Agents Studies
Abu Dhabi University
2023-2025
Qassim University
2020-2025
Khalifa University of Science and Technology
2023
Flinders Medical Centre
2018
Flinders University
2016-2018
The University of Texas at San Antonio
2017
Diethylnitrosamine (DEN) is a well-known hepatocarcinogen, and its oral administration causes severe liver damage including cancer. DEN induces the pathogenesis of through reactive oxygen species mediated inflammation modulation various biological activities. 6-Gingerol, major component ginger, reported to prevent diseases by reducing oxidative stress proinflammatory mediators. The present study investigated hepatoprotective effects 6-gingerol measurement stress, anti-inflammatory markers,...
Xenobiotic pollution in environment is a potential risk to marine life, and human health. Nanobiotechnology an advanced emerging solution for the removal of environmental pollutants. Adsorption-based technologies are being used alleviate global prevalence xenobiotics like dyes, due their high efficacy cost effectiveness. Current study explored nanobiochar syntehsized via ultrasonication centrifugation from rice husk dye water. It involves synthesis biochar Safranin, Malachite green, mixture...
Alzheimer's disease (AD) is a very common neurodegenerative disorder associated with memory loss and progressive decline in cognitive activity. The two major pathophysiological factors responsible for AD are amyloid plaques (comprising amyloid-beta aggregates) neurofibrillary tangles (consisting of hyperphosphorylated tau protein). Polyphenols, class naturally occurring compounds, immensely beneficial the treatment or management various disorders illnesses. Naturally sources polyphenols...
Physical exercise has been widely recognized for its positive effects on health and well-being. Recently, the impact of nervous system gained attention, with evidence indicating improvements in memory, neurogenesis, release "happiness hormones." One potential mediator these benefits is Irisin, a myokine induced by that can cross blood-brain barrier, reduce neuroinflammation, counteract neurodegeneration. The objective this study to conduct systematic review animal trials summarize...
The toxicological effects of nanoparticles (NPs) on humans, animals, and environment are largely unknown. Assessment NPs cytotoxicity depends the choice test system. Due to optical activity absorption values, they can influence classical assay. Eight were spiked in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) crystal violet assays tested with HaCaT human skin cells. MTT assay standard curve density (OD) measurements altered by presence trisilanol phenyl isooctyl...
Non-small-cell lung cancer (NSCLC) is the most common form of cancer, which a leading cause cancer-related deaths worldwide. Berberine an isoquinoline alkaloid that commercially available for use as supplement treatment diabetes and cardiovascular diseases. However, therapeutic benefits berberine are limited by its extremely low bioavailability toxicity at higher doses. Increasing evidence suggests incorporation drug compounds in liquid crystal nanoparticles provides new platform safe,...
Inflammation and oxidative stress are interrelated processes that represent the underlying causes of several chronic inflammatory diseases include asthma, cystic fibrosis, obstructive pulmonary disease (COPD), allergies, diabetes, cardiovascular diseases. Macrophages key initiators in body. When triggered by a stimulus such as bacterial lipopolysaccharides (LPS), these cells secrete cytokines namely TNF-α orchestrate cellular process. Simultaneously, pro-inflammatory stimuli induce...
Pharmaceutical personal care products (PPCPs) have increased in consumption due to the worldwide post-pandemic situation, marking them as chemical and pathogenic pollutants significantly higher concentrations than ever ecosystem. Considering inexplicable levels of these residues discharged into environment, concerns been raised regarding their probable ecotoxicity marine terrestrial life. A further concern is potential for developing spreading antibiotic-resistant microorganisms genes...
Onosma bracteata Wall. is an important medicinal and immunity-enhancing herbs. This plant commonly used in the preparation of traditional Ayurvedic drugs to treat numerous diseases. Inspired by properties this plant, present study aimed investigate antiproliferative potential primary molecular mechanisms apoptotic induction against human osteosarcoma (MG-63) cells. Among all fractions isolated from O. bracteata, ethyl acetate fraction (Obea) showed good antioxidant activity superoxide...
Kaempferol, a flavonoid, contains plethora of therapeutic properties and has demonstrated its efficacy against cancer. This study aims to unravel the molecular targets that are being modulated by kaempferol on HeLa cells. Various assays were performed, namely: MTT assay, flow cytometry analyze DNA content quantitate apoptosis. Quantitative PCR protein profiling performed evaluate manifestation different genes involved in apoptosis, cell growth inflammation. Kaempferol exhibited reduction...
(1) Background: Inflammation is one of the primary responses immune system and plays a key role in pathophysiology various diseases. Recent reports suggest that phytochemicals exhibit promising anti-inflammatory immunomodulation activities with relatively few undesirable effects, thus offering viable option to deal inflammation associated The current study evaluates immunomodulatory effects withaferin A (WA) cells extracted from BALB/c mice. (2) Methods: MTT assays were performed assess cell...