A5025813701- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- Fluoride Effects and Removal
- Metal-Organic Frameworks: Synthesis and Applications
- Supramolecular Chemistry and Complexes
- Analytical Chemistry and Sensors
- Protein Interaction Studies and Fluorescence Analysis
- Carbon and Quantum Dots Applications
- Neonatal Health and Biochemistry
- Hemoglobin structure and function
- Amino Acid Enzymes and Metabolism
- Metabolomics and Mass Spectrometry Studies
- Nanocluster Synthesis and Applications
- Graphene and Nanomaterials Applications
- Adsorption and biosorption for pollutant removal
- Lanthanide and Transition Metal Complexes
- Click Chemistry and Applications
- Cell death mechanisms and regulation
- Polyamine Metabolism and Applications
- Bioactive natural compounds
- Advanced biosensing and bioanalysis techniques
- Synthesis and Biological Evaluation
- Photochemistry and Electron Transfer Studies
- Free Radicals and Antioxidants
- Analytical chemistry methods development
Guru Nanak Dev University
2019-2025
Polish Academy of Sciences
2025
Institute of Organic Chemistry
2025
Institute of Nano Science and Technology
2023-2024
Center for Nano Science and Technology
2023
Indian Institute of Science Education and Research Mohali
2023
Centre of Advanced Studies
2020
Indian Institute of Management Amritsar
2020
Carbon Dots (CDs) are a class of carbon-based nanostructure known as zero-dimensional nanomaterial and have great potential in the field targeted chemotherapy. CDs been extensively explored for bioimaging, sensing, therapy due to their high quantum yield, low cytotoxicity, water solubility, good photostability, tunable excitation wavelength-dependent emission properties. conjugated with various anticancer drugs such Doxorubicin (DOX), Epirubicin Temozolomide, Protoporphyrin IX (PpIX),...
Picric acid, due to its low p K a value, possesses distinct physicochemical features from all other nitroaromatic derivatives, enabling the design of fluorescent probes for sensitive and selective detection.
Serum albumins, such as bovine serum albumin (BSA) and human (HSA), play a crucial role in various biological processes. Discrimination between BSA HSA is challenging due to their similar structures reactivity. Here, we report mitochondria-targeted red fluorescent tripodal nanoprobe DMAS-TP, forming spherical nano-aggregates (∼90 nm) water for discrimination of over detection imaging viscosity HeLa cells. DMAS-TP exhibits an ∼56-fold fluorescence intensity increase 95% glycerol compared...
Paper strips coated with the red-fluorescent probe<bold>DMAS-TP</bold>display a distinct blue fluorescence 2,4,6-trinitrophenol and<bold>SiO2@DMAS-TP</bold>NPs to visualize latent fingerprints up level 3.
Onosma bracteata Wall. is an important medicinal and immunity-enhancing herbs. This plant commonly used in the preparation of traditional Ayurvedic drugs to treat numerous diseases. Inspired by properties this plant, present study aimed investigate antiproliferative potential primary molecular mechanisms apoptotic induction against human osteosarcoma (MG-63) cells. Among all fractions isolated from O. bracteata, ethyl acetate fraction (Obea) showed good antioxidant activity superoxide...
Abstract Background Cancer is a persistent global health challenge, demanding continuous exploration of innovative therapeutic strategies. Hydroxytyrosol (HT), derived from olive oil, has garnered attention for its potent antioxidant and anti-inflammatory properties, revitalizing interest due to recent breakthroughs in comprehending intricate anticancer mechanisms. Main Body This review conducts detailed analysis hydroxytyrosol’s molecular mechanisms cancer. Delve into the complex pathways...
Abstract Onosma bracteata Wall. (Boraginaceae family) is one of the important constituents Ayurvedic drugs which enhance immunity. Among all fractions isolated from O. , ethyl acetate fraction ( Obea ) showed good antioxidant activity in Superoxide radical scavenging assay and Lipid peroxidation with EC 50 value 95.12 80.67 µg/ml, respectively. Silica gel column chromatography yielded ObD1 was characterized as Di-isobutyl phthalate (DIBP) using NMR, FTIR HRMS spectroscopic techniques. DIBP...
Probe <bold>DMAS-DP</bold> in water shows highly selective decrease absorbance (475 nm) and fluorescence intensity (615 with 2,4,6-trinitrophenol colour change from red to yellow (visible light) fluorescent black (365 nm light).
The flexibility in dipodal DPDM results its contrasting behavior towards serum albumins comparison to monopodal MPMB.
Fluoride (F–) is a unique analyte because when in small quantities, it beneficial and harmful larger or negligible leaving essential for dual-purpose detection removal from water sample to prevent fluoride-caused health risks. F– using organic molecules hybrid materials are extensively reported the literature, but very few reports discuss removal. Functional nanomaterials (FNM) based on nanoparticles, metal-organic frameworks, carbon dots conjugated with fluorophore moiety largely used these...
Abstract 1,2,4‐Triazolopyrimidines scaffold spaciously acknowledged with anticancer, antimalarial, antitubercular and many other fascinating biological applications in recent years (2015–2022). Moreover, numerous mild synthetic methodologies reported, which has been summarized as (i) condensation of 2‐amino‐1,2,4‐triazole or 5‐amino‐1,2,4‐triazole 1,3‐dielectrophilic equivalents like 1,3‐diketones, β‐ketoester (ii) oxidative‐cyclization hydrazones related analogues. This review would...
A BTNN probe undergoes a 146 times increase in fluorescence intensity at 530 nm on lowering the pH from 7.0 to 2.0 and has been deployed for bioimaging of MG-63 live cells E. coli bacteria different levels.
Red and NIR active dipod–SDS self-assemblies can detect spermine – a vital biomarker for clinical diagnosis of cancer estimating food spoilage.
Tetracyanobutadiene (TCBD)-appended main-chain polymers offer superior chromophore properties compared to side-chain polymers, but their development is hindered by challenges in complex synthesis and customization. We present a solution using urea-appended alkyne polymer p-alkyne for easier customization sensing applications. Our method involves synthesizing containing TCBD extended-TCBD (eTCBD) units via p-alkyne, which, on treatment with TCNE TCNQ, yields p-TCBD p-eTCBD respectively. These...
Fluoride (F–) is a unique analyte because when in small quantities, it beneficial and harmful larger or negligible leaving essential for dual-purpose detection removal from water sample to prevent fluoride-caused health risks. F– using organic molecules hybrid materials are extensively reported the literature, but very few reports discuss removal. Functional nanomaterials (FNM) based on nanoparticles, metal-organic frameworks, carbon dots conjugated with fluorophore moiety largely used these...
Abstract Fluoride (F − ) is a unique analyte because when in small quantities, it beneficial and harmful larger or negligible leaving essential for dual‐purpose detection removal from water sample to prevent fluoride‐caused health risks. F using organic molecules hybrid materials are extensively reported the literature, but very few reports discuss removal. Functional nanomaterials (FNM) based on nanoparticles, metal‐organic frameworks, carbon dots conjugated with fluorophore moiety largely...
Two-in-one: This review discusses a recent development in the area of functional nanomaterials that are capable detecting and removing fluoride through use agglomeration, electrostatic, H-bonding, ion exchange, coordination π-π stacking interactions. unique approach provides an effective way to detect remove from water environment. More information can be found Review by Govindasamy Jayamurugan et al.