A5086391070- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Uterine Myomas and Treatments
- Cervical Cancer and HPV Research
- Intraperitoneal and Appendiceal Malignancies
- Endometriosis Research and Treatment
- Reproductive Biology and Fertility
- PARP inhibition in cancer therapy
- BRCA gene mutations in cancer
- Colorectal and Anal Carcinomas
- Gynecological conditions and treatments
- Ectopic Pregnancy Diagnosis and Management
- Brain Metastases and Treatment
- Gestational Trophoblastic Disease Studies
- Testicular diseases and treatments
- Lung Cancer Research Studies
- Ovarian function and disorders
- Sarcoma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Urinary and Genital Oncology Studies
- Neuroendocrine Tumor Research Advances
- Urologic and reproductive health conditions
- Prenatal Screening and Diagnostics
- Renal cell carcinoma treatment
- Cancer Risks and Factors
Istituto Tumori Bari
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2025
University of Bari Aldo Moro
2016-2025
Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari
2008-2024
Gynecologic Oncology Group
2004-2023
Ospedale San Paolo
2021
Tumori Foundation
2018
University of Campania "Luigi Vanvitelli"
2017
Health and Human Development (2HD) Research Network
2014
Radiation Oncology Institute
2014
Pelvic lymph nodes are the most common site of extrauterine tumor spread in early-stage endometrial cancer, but clinical impact lymphadenectomy has not been addressed randomized studies. We conducted a trial to determine whether addition pelvic systematic standard hysterectomy with bilateral salpingo-oophorectomy improves overall and disease-free survival. From October 1, 1996, through March 31, 2006, 514 eligible patients preoperative International Federation Gynecology Obstetrics stage I...
Distant metastases are unusual at presentation and during the course of ovarian carcinoma. The aim present study was to determine incidence prognostic factors distant consistent with stage IV disease in cancer patients. A retrospective chart review conducted on 162 patients epithelial carcinoma treated our Unit between 1991 2000. Pertinent clinical information, pathologic data, treatment, for survival following documentation metastatic were collected. significance association status various...
This study aims to identify prognostic factors and develop a risk model predicting survival in patients undergoing secondary cytoreductive surgery (SCR) for recurrent epithelial ovarian cancer. Individual data of 1100 with cancer progression-free interval at least 6 months who underwent SCR were pooled analysed. A simplified scoring system each independent factor was developed according its coefficient. Internal validation performed assess the discrimination model. Complete strongly...
Recent studies have shown the importance of microbiota in women's health. Indeed, persistence Human Papilloma Virus (HPV)-related lesions patients with dysbiosis can be antechamber to cervical cancer. The aim this study was evaluate whether long term administration oral Lactobacillus crispatus restore eubiosis women HPV infections and hence achieve viral clearance.In total, 160 affected by were enrolled at Department Gynecological Obstetrics "San Paolo" Hospital, Italy between February 2021...
This study aimed to investigate the outcome of patients with malignant ovarian germ cell tumors (MOGCTs) and define risk factors for recurrence.A total 123 MOGCTs were retrospectively reviewed among MITO centers. Eighty-one had primary treatment in a center, whereas other 42 referred adjuvant chemotherapy or recurrence. The clinicopathologic characteristics evaluated association relapse death.Median age was 24 years (range, 11-76 years). Forty-nine (39.8%) dysgerminomas, 35 (28.5%) immature...
Purpose Platinum-based chemotherapy (PBC) for patients with progressing ovarian cancer (OC) is more effective a longer time interval from previous platinum treatment (platinum-free [PFI]). In 1999, it was hypothesized that prolonging PFI single-agent non-PBC (NPBC) may offer strategy to improve overall outcome. MITO-8 aimed verify this hypothesis commonly used in clinical practice although has not been prospectively tested. Methods an open-label, prospective, randomized, superiority trial....
Women with polycystic ovary syndrome (PCOS) have several cardiovascular disease risk factors. Since hyperhomocysteinemia is associated early atherosclerosis, it was postulated that the homocysteine levels are higher in PCOS patients than control subjects which, therefore, may explain risk. Thirty-five women and 20 healthy were studied. Endocrine assays, lipid profile, insulin level determinations, ultrasound evaluation performed all subjects. We found significantly mean plasma concentrations...