Di Li

ORCID: 0000-0001-5764-7751
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About
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Research Areas
  • Nutritional Studies and Diet
  • Fatty Acid Research and Health
  • Diet and metabolism studies
  • Nutrition and Health in Aging
  • Cervical Cancer and HPV Research
  • Stress Responses and Cortisol
  • Vitamin D Research Studies
  • Hormonal and reproductive studies
  • Eicosanoids and Hypertension Pharmacology
  • Antioxidant Activity and Oxidative Stress
  • Nitric Oxide and Endothelin Effects
  • Cancer-related molecular mechanisms research
  • Tuberculosis Research and Epidemiology
  • Tryptophan and brain disorders
  • Phagocytosis and Immune Regulation
  • Fetal and Pediatric Neurological Disorders
  • Sperm and Testicular Function
  • Liver Disease Diagnosis and Treatment
  • Allergic Rhinitis and Sensitization
  • Per- and polyfluoroalkyl substances research
  • Garlic and Onion Studies
  • GDF15 and Related Biomarkers
  • Neurological diseases and metabolism
  • Amyotrophic Lateral Sclerosis Research
  • Lysosomal Storage Disorders Research

Lanzhou University
2024-2025

Chinese People's Armed Police Force
2024

Tianjin University
2024

Renmin Hospital of Wuhan University
2017-2023

Wuhan University
2017-2023

Capital Medical University
2020-2021

Beijing Children’s Hospital
2020

Harbin Medical University
2019

Qiqihar Medical University
2019

Sun Yat-sen Memorial Hospital
2015

Testosterone deficiency can lead to depressive symptoms in humans; however, the causes of this are incompletely understood. Here, we isolated Mycobacterium neoaurum from fecal samples testosterone-deficient patients with depression and showed that strain could degrade testosterone vitro. Furthermore, gavaging rats M. reduced their serum brain levels induced depression-like behaviors. We identified gene encoding 3β-hydroxysteroid dehydrogenase (3β-HSD) as enzyme causing degradation....

10.1016/j.chom.2022.01.001 article EN cc-by-nc-nd Cell Host & Microbe 2022-02-01

The main findings of this study were that we clarified the associations different bacterial species with expression human papillomavirus (HPV) oncogenes at stages cervical cancer. Along severity lesions, abundance genus and Lactobacillus obviously declined, while aerobic anaerobic bacteria, as well prevalence HPV E6/E7 oncogene, increased dramatically.

10.1128/spectrum.00151-22 article EN cc-by Microbiology Spectrum 2022-08-29

Objective Multiple observational studies have demonstrated an association between type 2 diabetes mellitus (T2DM) and chronic liver diseases (CLDs). However, the causality of T2DM on CLDs remained unknown in various ethnic groups. Methods We obtained instrumental variables for conducted a two-sample mendelian randomization (MR) study to examine causal effect nonalcoholic fatty disease (NAFLD), hepatocellular carcinoma (HCC), viral hepatitis, hepatitis B virus (HBV) infection, C (HCV)...

10.3389/fendo.2024.1338465 article EN cc-by Frontiers in Endocrinology 2024-03-01

Objectives T‐ SPOT . TB is a promising diagnosis tool to identify both pulmonary tuberculosis and extrapulmonary tuberculosis, as well latent tuberculosis; however, the factors that affect results of remains unclear. In this study, we aim figure out risk factor for active Methods A total 349 patients were recruited between January 1st, 2016 22st, 2017 at Renmin Hospital Wuhan University, including 98 subjects with 251 non‐ disease, received (Oxford Immunotec Ltd). Statistics analyzed by SPSS...

10.1002/jcla.22273 article EN Journal of Clinical Laboratory Analysis 2017-06-08

Background The recent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak has caused millions of deaths and greatly influenced the timely diagnosis treatment other diseases. Throughout pandemic, there was a dramatic reduction in prevalence several sexually transmitted infections. However, impact ongoing pandemic on human papillomavirus (HPV) infection rates not been investigated thus far. Materials Methods We retrospectively collected data regarding HPV cervical cancer...

10.3389/fmed.2022.799736 article EN cc-by Frontiers in Medicine 2022-04-11

Abstract The emergence and spread of drug-resistant Mycobacterium tuberculosis is global concern. To improve the understanding drug resistance in Mycobacteria, numerous studies have been performed to discover diagnostic markers genetic determinants associated with anti-tuberculosis drug. However, related information scattered a massive body literature, which inconvenient for researchers investigate molecular mechanism resistance. Therefore, we manually collected 1707 curated associations...

10.1093/database/baz074 article EN cc-by Database 2019-01-01

Cervical cancer is one of the most frequent malignancies in women, particularly metastasis resulting a poor prognosis. However, clinical characteristics cervical patients with advanced liver have not been well investigated. We aimed to evaluate incidence, risk and prognostic factors for hepatic patients.The features diagnosed were collected from Surveillance, Epidemiology End Result (SEER) public database between 2010 2015. Multivariate logistic Cox regression models performed identify...

10.1186/s12885-021-08127-6 article EN cc-by BMC Cancer 2021-04-16

China's most frequent malignancy is gastric cancer (GC), which has a very poor survival rate, and the rate for patients with advanced GC dismal. Pyroptosis been connected to genesis development of cancer. The function pyroptosis-related long non-coding RNAs (PRLs) in GC, on other hand, remains uncertain.

10.4240/wjgs.v16.i7.2281 article EN World Journal of Gastrointestinal Surgery 2024-07-22

Background: A inverse association between depressive symptoms and dietary fiber intake was reported in general population, but this are unstudied midlife women. This study designed to investigate the of with Methods: Data for cross-sectional were retrieved from baseline assessment Study Women’s Health Across Nation (SWAN). Linear regressions used examine Center Epidemiological Studies-Depression (CES-D) score. Logistic regression restricted cubic spline models (CES-D score≥16). Results:...

10.3389/fnins.2020.00373 article EN cc-by Frontiers in Neuroscience 2020-05-06

Background: Selenoprotein N-related myopathies (SEPN1-RMs) are a subset of congenital caused by mutations N gene (SELENON or SEPN1). Clinical phenotype is considered as highly consistent and little attention has been given to the extramuscular abnormalities. Methods: We reported clinical, histopathological, genetic features four Chinese patients with SEPN1-RM performed literature review on delayed respiratory insufficiency involvement. Results: A total exhibited both typical atypical...

10.3389/fneur.2021.766942 article EN cc-by Frontiers in Neurology 2021-11-19
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