Ana Medel-Martínez

ORCID: 0000-0001-5783-4020
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About
Contact & Profiles
Research Areas
  • COVID-19 Impact on Reproduction
  • Pregnancy and preeclampsia studies
  • COVID-19 Clinical Research Studies
  • Reproductive System and Pregnancy
  • Extracellular vesicles in disease
  • Long-Term Effects of COVID-19
  • RNA Interference and Gene Delivery
  • Cancer Research and Treatments
  • COVID-19 and Mental Health
  • MicroRNA in disease regulation
  • Diverse Scientific Research Studies
  • Virus-based gene therapy research
  • Maternal Mental Health During Pregnancy and Postpartum
  • bioluminescence and chemiluminescence research
  • Cardiovascular Issues in Pregnancy
  • COVID-19 and healthcare impacts
  • Viral Infections and Vectors
  • Preterm Birth and Chorioamnionitis

Instituto de Investigación Sanitaria Aragón
2022-2025

Instituto Aragonés de Ciencias de la Salud
2021-2024

Instituto de Nanociencia y Materiales de Aragón
2020

Universidad de Zaragoza
2020

Zaragoza Logistics Center
2020

Exosomes are cell-derived extracellular vesicles (EVs) with diameters between 30 and 120 nm. In recent years, several studies have evaluated the therapeutic potential of exosomes derived from different fluids due to their low immunogenicity high biocompatibility. However, producing on a large scale is still challenging. One which they could be isolated in quantities milk. Moreover, regeneration well-known property The present work seeks optimize method for isolating bovine human milk,...

10.3390/biom14070810 article EN cc-by Biomolecules 2024-07-08

<b><i>Introduction:</i></b> Studies described an increased frequency of hypertensive disorders pregnancy (HDP) after a COVID-19 episode. There is limited evidence about SARS-CoV-2 viral load in placenta. This study aimed to investigate the relationship between placenta and clinical development HDP throughout different periods gestation. <b><i>Methods:</i></b> case-control women with without gestational infection diagnosed by RT-PCR during...

10.1159/000520179 article EN Fetal Diagnosis and Therapy 2021-01-01

Due to their ease of isolation and properties, mesenchymal stem cells (MSCs) have been widely investigated. MSCs proved capable migration towards areas inflammation, including tumors. Therefore, they suggested as vectors carry therapies, specifically neoplasias. As most the individuals joining clinical trials that use for cancer other pathologies are carefully recruited do not suffer from diseases, here we decided study safety application iv-injected in animals simultaneously induced with...

10.3390/ijms23031682 article EN International Journal of Molecular Sciences 2022-01-31

The original SARS-CoV-2 lineages have been replaced by successive variants of concern (VOCs) over time. aim this study was to perform an assessment the placental infection according predominant variant at moment COVID-19 diagnosis. This a prospective SARS-CoV-2-positive pregnant women between March 2020 and 2022. population divided into pregnancies affected disease during (Pre-VOC group) after December (VOC group). presence virus assessed RT-PCR, viral determined whole genome sequencing. A...

10.3390/v15091918 article EN cc-by Viruses 2023-09-13

Post-coronavirus disease condition (PCC) continues to affect many people globally, yet there remains a lack of diagnostic biomarkers distinguish PCC from those recovered acute COVID-19. This study compared between two age- and gender-matched groups: individuals within three months COVID-19 in 2020 (

10.1016/j.isci.2024.110839 article EN cc-by-nc iScience 2024-08-30

Introduction Suspected preterm labour (SPL) is an obstetric complication that occurs in 9% of all pregnancies and the leading cause antenatal hospital admissions. More than half women with SPL deliver a premature baby which known risk factor for developing cardiovascular metabolic disorders childhood later adult life. On other hand, these will at term, labelled as ‘false labour’. Although this has been thought to be benign condition, accumulating evidence reported recent years showed...

10.1136/bmjopen-2024-087430 article EN cc-by-nc-nd BMJ Open 2024-11-01

Background: The persistence or development of new symptoms three months after the initial acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection is referred to as post-coronavirus disease (COVID) condition (PCC). identification biomarkers specific for occurrence PCC vital proceed in future towards prediction its evolution. T-cell dysfunction, cytokine imbalance, and coagulation defects have been reported PCC. While a wide variety associated with has described, diagnostic...

10.2139/ssrn.4538239 preprint EN 2023-01-01
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