A5017810934- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Chemical Synthesis and Analysis
- Molecular Sensors and Ion Detection
- Supramolecular Chemistry and Complexes
- Luminescence and Fluorescent Materials
- Click Chemistry and Applications
- Conducting polymers and applications
- Crystallography and molecular interactions
- Metal-Organic Frameworks: Synthesis and Applications
- Covalent Organic Framework Applications
- Organic Light-Emitting Diodes Research
- Synthesis and Characterization of Heterocyclic Compounds
- Organic Electronics and Photovoltaics
- Porphyrin and Phthalocyanine Chemistry
- Antimicrobial Peptides and Activities
- Supramolecular Self-Assembly in Materials
- Mass Spectrometry Techniques and Applications
- Peptidase Inhibition and Analysis
- Molecular Junctions and Nanostructures
- Synthesis and biological activity
- Enzyme-mediated dye degradation
- Polymer Surface Interaction Studies
- Phenothiazines and Benzothiazines Synthesis and Activities
- Lanthanide and Transition Metal Complexes
Babeș-Bolyai University
2015-2024
Spitalul Clinic Județean de Urgență Cluj-Napoca
2016-2021
Laboratoire de Chimie
2020
University of Bucharest
2013-2015
Technical University of Munich
2011-2012
Polydopamine (PDA) formed by the oxidation of dopamine is an important polymer, in particular, for coating various surfaces. It composed dihydroxyindole, indoledione, and units, which are assumed to be covalently linked. Although PDA has been applied a manifold way, its structure still under discussion. Similarities have observed melanins/eumelanins as naturally occurring, deeply colored polymer pigments derived from l-DOPA. Recently, alternative was proposed wherein dihydroxyindoline,...
A literature survey of the cross-coupling reactions in preparation 1,3,4-oxadiazole compounds as useful materials for OLEDs is described.
Palladium nanoparticles entrapped in porous aromatic frameworks (PAFs) or covalent organic may promote heterogeneous catalytic reactions. However, preparing such materials as active nanocatalysts usually requires additional steps for palladium entrapment and reduction. This paper reports a new approach, simple procedure leading to the self-entrapment of Pd within PAF structure. Thus, selected Sonogashira synthesis affords PAF-entrapped that can catalyze C-C Suzuki-Miyaura cross-coupling...
Yellow laccases lack the typical blue type 1 Cu absorption band around 600 nm; however, multi-copper oxidases with laccase properties have been reported. We provide first evidence that yellow isolated from Sclerotinia sclerotiorum is obtained a form by covalent, but nevertheless reversible modification phenolic product. After separating phenolics extracellular medium, obtained. With ABTS as model substrate for this enzyme, non-natural purple adduct formed spectrum nearly identical to of 1:1...
Abstract We report here the synthesis and biochemical properties of a new peptidyl activity‐based probe 1 for SUMO proteases, SENPs. The has at its C terminus glycine‐derived fluoromethylketone moiety as reactive group designed to target active‐site cysteine Based on study interactions between SENPs SUMOs, we introduced further design elements that allow selectively low micromolar high nanomolar concentrations. Moreover, out‐competes SUMO1 from reversible SUMO1–SENP1 complex, thus suggesting...
Up till 20 years ago, in order to endow molecules with function there were two mainstream lines of thought. One was rationally design the positioning chemical functionalities within candidate molecules, followed by an iterative synthesis-optimization process. The second use a "brutal force" approach combinatorial chemistry coupled advanced screening for function. Although both methods provided important results, "rational design" often resulted time-consuming efforts modeling and synthesis...
We present herein synthesis of novel [2+2] and [3+3] N-acylhydrazone-based macrocycles using a pool dialdehydes dihydrazides, under thermodynamic control. The resulted macrocycles, which were assigned triangular rectangular...
A bimodal (micro/mesoporous) COF was synthesized by coupling tetrakis-1,3,5,7-(4′-iodophenyl)adamantane with 4,4′-diethynylbiphenyl following a Sonogashira protocol. The preparation strategy led, however, to the incomplete recovery of palladium catalyst and ICP-OES analysis indicated that around 0.1 wt% remained inside pores. Noteworthily, remnant is still accessible can be valorised in additional catalytic reactions like hydrogenation nitrostyrene. Further deposition 0.5 active metals (like...
Bis-amidine and bis-carboxylate derivatives have been studied in this work to extend the knowledge of charge-assisted hydrogen bonding (CAHB) which counts among strongest noncovalent observed so far arises from combination two well-identified types interactions, namely, electrostatic attraction bonding. The formation such bridges associated macrocycles were screened for substituted (1) nonsubstituted (2) bis-benzamidines through use isomeric proton acceptors aromatic bis-carboxylic (3–6)...
Reaction between ortho-phthalaldehyde and various aroylhydrazines unexpectedly yields N-(1-(2-aryl-hydrazono)isoindolin-2-yl)benzamides as major products along with the predictable 1,2-bis-aroylhydrazones. NMR investigation of reaction indicate presence a mixture geometrical isomers, in ratios. Single crystal X-ray diffraction confirms proposed structure indicates Z configuration C═N double bond substitutents. Optimization condensation conditions enabled quantitative isolation cyclic isomer....
Abstract Spirobifluorene‐based porous organic polymers (POP) were synthesized following two different protocols; the acetylenic coupling reaction conditions and Sonogashira cross‐coupling reaction. These utilized as support for hydrogenation of a series species containing unsaturated C=C C=O bonds (4‐nitrostyrene, 4‐bromobenzophenone, acetophenone, 7‐nitro‐1‐tetralone 1,2‐naphtoquinone confirmed their efficiency). POP1 prepared via copper‐catalysis protocol was completely inactive, while...
Abstract This review presents a survey through macrocyclic and interlocked structures containing 1,4,5,8‐naphthalendiimide residues from the synthetic point of view also illustrates structural particularities that dictate their main applications in supramolecular, biological materials chemistry. The paper is organised as comprehensive description macrocycles, cyclophanes, catenanes, rotaxanes metallamacrocycles along with other types supramolecular architectures. For each category, we...
Supramolecular assemblies of 2,7-dipyridylfluorene with diiodotetrafluorobenzene isomers were obtained by mechanochemical synthesis, and their structures determined single crystal X-ray diffraction. The contribution specific noncovalent interactions between different building blocks to the stability solid-state packing behaviors supramolecular catemers was evaluated theoretical methods, which confirm geometries interactional bonding observed in diffraction structures.
An easy and powerful access to 3,3′,6,6′-tetrasubstituted 9,9′-spirobifluorene derivatives with tetrahedral orientation of the peripheral groups (i.e., −I, −CN, −NO2, −CH═O, −COOH, −C≡CH, −4-Py) was developed. The NMR HRMS results are in agreement proposed formula solid-state molecular structures obtained by single-crystal X-ray diffraction. They form solids self-assembled via exclusive hydrophobic interactions. Solid-state selection adaptation can be on basis variable compact packing...
A new type of polymer containing a number functional groups with orthogonal reactivity, allowing linkage to several functionalities.
Bis-<italic>N</italic>-acylhydrazones bearing different substituents were found to display colour emissions, through ESIPT or AIE, as a result of conformation switching, triggered by physical stimuli.
Profluorescent nitroxides containing 2,5-diaryl-1,3,4-oxadiazoles as fluorophore units were synthesized and characterized actively responsive probes to reducing agents.
Exciting β-HCH–anion recognition <italic>via</italic> cooperative aliphatic C–H–anion contacts is discussed.