A5065539463- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Retinal Imaging and Analysis
- Intraocular Surgery and Lenses
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Macular Surgery
- Retinal Development and Disorders
- Glaucoma and retinal disorders
- Connexins and lens biology
- Systemic Lupus Erythematosus Research
- Cerebral Venous Sinus Thrombosis
- Vascular Malformations Diagnosis and Treatment
- Drug-Induced Ocular Toxicity
- Ocular Disorders and Treatments
- Cancer and Skin Lesions
- Healthcare Systems and Reforms
- Ocular Infections and Treatments
- Fungal Infections and Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Health, Environment, Cognitive Aging
- Pneumocystis jirovecii pneumonia detection and treatment
- Intracranial Aneurysms: Treatment and Complications
- Neuroscience and Neural Engineering
- Sphingolipid Metabolism and Signaling
- Acute Ischemic Stroke Management
Campbell University
2020-2023
Southern Eye Associates
2013-2023
FirstHealth of the Carolinas
2013
University of Missouri
2011-2013
Retina Institute
2009-2010
Washington University in St. Louis
2007-2010
University of Washington
2010
The University of Kansas Health System
2009
Doheny Eye Institute
2002-2005
University of Southern California
2002
PurposeTo evaluate 2-year efficacy, durability, and safety of the bispecific antibody faricimab, which inhibits both angiopoietin-2 VEGF-A.DesignTENAYA (ClinicalTrials.gov identifier, NCT03823287) LUCERNE NCT03823300) were identically designed, randomized, double-masked, active comparator-controlled phase 3 noninferiority trials.ParticipantsTreatment-naive patients with neovascular age-related macular degeneration (nAMD) 50 years age or older.MethodsPatients randomized (1:1) to intravitreal...
To examine the utilization of bevacizumab and ranibizumab disease monitoring in patients with branch or central retinal vein occlusion (BRVO/CRVO) diabetic macular edema (DME) clinical practice.This retrospective claims analysis included newly diagnosed one more injections. Bevacizumab was assessed by year first injection: 2008-2010 cohorts (12-month follow-up), January to June 2011 cohort (6-month follow-up). The main outcome measures were mean annual numbers injections, ophthalmologist...
To determine monitoring and treatment patterns vision outcomes in real-world patients initiating anti-vascular endothelial growth factor (anti-VEGF) therapy for diabetic macular edema (DME).Retrospective interventional cohort study.Setting: Electronic medical record analysis of Geisinger Health System data.A total 110 (121 study eyes) intravitreal ranibizumab or bevacizumab DME during January 2007‒May 2012, with baseline corrected visual acuity 20/40 to 20/320, ≥1 ophthalmologist visit...
PurposeTo assess anti-vascular endothelial growth factor (VEGF) management patterns and anatomic visual acuity (VA) outcomes among patients with neovascular age-related macular degeneration (nAMD) in United States clinical practice.DesignRetrospective observational cohort study.ParticipantsPatients (N = 30 106) initiating intravitreal anti-VEGF treatment for nAMD between October 2009 November 2016.MethodsAnalysis of longitudinal electronic health records from USRetina.Main Outcome...
To evaluate plaque movement as a potential factor in local failure using intraoperative ultrasonography at insertion and removal.Prospective study of 162 patients with uveal melanoma undergoing B-scan removal iodine 125 plaques.Tilting the posterior edge more than 1.0 mm away from sclera was detected 15 (9%) 85 (53%) (P < .001). Factors associated tilt included male sex = .009), decreased tumor distance to fovea optic disc .001 for both), notched .001), episcleral hematoma .009). Plaque...
In Brief Purpose: To determine whether the gauge of vitrectomy instrumentation is associated with progression nuclear sclerotic cataract. Methods: A prospective interventional and observational study patients undergoing surgery for various retinal conditions. Patients had Scheimpflug lens photography in operated fellow eye at baseline 6 months 12 after surgery. Results: Of 42 eyes included analysis, 11 20-gauge surgery, 22 23-gauge 9 25-gauge all eyes, led to significant cataract, compared...
The status of the macula is a significant factor in determining final visual outcomes rhegmatogenous retinal detachment (RRD) and should be considered timing surgical repair. Several studies have shown that macula-involving RRDs attain similar anatomic when surgery performed within seven days as compared to emergent (within 24 hours). In contrast, prior macular macula-sparing generally yields best outcomes. case RRDs, it not clear how long may remain attached, therefore, standard practice...
BACKGROUND: New treatment alternatives have revolutionized the management of nAMD. However, there is limited evidence on clinical and economic burden nAMD in commercially insured US patients. OBJECTIVES: To examine patients with by disease status patient population to identify drivers nAMD-related costs. METHODS: Patients at least 1 International Classification Diseases, 10th Revision Clinical Modification (ICD-10-CM) diagnosis for were identified from IQVIA PharMetrics Plus database between...
<h3>Background/Aims</h3> To evaluate the treatment course of patients with primary rhegmatogenous retinal detachment (RRD) that re-detach after initial surgery. <h3>Methods</h3> Patients were divided into three groups based on surgical treatment: scleral buckle procedure (SBP) (63 eyes), pars plana vitrectomy (PPV) (88 eyes) and combined SBP/PPV (135 eyes). Charts reviewed for a mean follow-up 12 months. <h3>Results</h3> Average number secondary procedures to achieve anatomical success was...
Patients taking hydroxychloroquine (HCQ) are at risk of developing classic bull's eye maculopathy. Currently, the standard Amsler grid (AG) is one most useful methods to identify such lesions. However, AG a suprathreshold target and may not detect relative central scotomas. The aim this study was determine if threshold (TAG) test, which varies light transmission through two cross polarising filters, allows increased detection scotomas caused by HCQ toxicity.56 rheumatological patients 12...
In Brief Purpose: To evaluate the anatomic and visual outcomes of patients treated with triamcinolone-assisted internal membrane peeling for macular hole. Methods: A retrospective chart review 37 consecutive cases done by a single vitreoretinal surgeon idiopathic All surgery involved limiting peeling. had at least 3-month follow-up. Main outcome measures included hole closure, acuity, operative complications. Results: Mean follow-up was 11 months (range, 3–56 months). Anatomic closure...
BACKGROUND AND OBJECTIVE: Patients with neovascular age-related macular degeneration (AMD) require frequent follow-up and regular anti-VEGF injections for optimal outcomes. Although studies suggest that injection frequency is suboptimal in clinical practice, monitoring this setting unclear. This study evaluates annual patterns between 2008 2011. PATIENTS METHODS: retrospective claims analysis included newly diagnosed AMD patients at least one intravitreal bevacizumab or ranibizumab (8,811...