A5077094787- Pregnancy and preeclampsia studies
- Maternal and fetal healthcare
- Prenatal Screening and Diagnostics
- Urological Disorders and Treatments
- Catalytic Cross-Coupling Reactions
- Ovarian cancer diagnosis and treatment
- Ectopic Pregnancy Diagnosis and Management
- Fetal and Pediatric Neurological Disorders
- Reproductive System and Pregnancy
- Lung Cancer Research Studies
- Catalytic C–H Functionalization Methods
- Endometriosis Research and Treatment
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Urinary and Genital Oncology Studies
- Neuroendocrine Tumor Research Advances
- Assisted Reproductive Technology and Twin Pregnancy
- Nephrotoxicity and Medicinal Plants
- Neonatal and fetal brain pathology
- Pediatric Urology and Nephrology Studies
- Congenital Diaphragmatic Hernia Studies
- Asymmetric Hydrogenation and Catalysis
- Medicinal Plants and Neuroprotection
- Genetics and Neurodevelopmental Disorders
- Autoimmune Neurological Disorders and Treatments
Sichuan University
2016-2025
West China Second University Hospital of Sichuan University
2017-2025
Guangdong Pharmaceutical University
2024-2025
Guangdong Institute for Drug Control
2024
Zhongshan People's Hospital
2024
State Key Laboratory of Biotherapy
2022
Ministry of Education of the People's Republic of China
2022
Sun Yat-sen University
2014-2021
People's Hospital of Bishan District
2021
The First Affiliated Hospital, Sun Yat-sen University
2014-2021
ObjectiveWe aimed to determine the safety of Vaginal natural orifice transluminal endoscopic surgery (vNOTES) in terms Enhanced Recovery after Surgery (ERAS) concept for tubal pregnancy and provide a detailed process vNOTES surgery, including experience key points surgeons performing this procedure.MethodsThe Longitudinal Natural Orifice Transluminal Endoscopic Study (LovNOTESS), which was conducted Chengdu, China. A total 219 patients who underwent ectopic between September 2021 March 2022....
Xanthoceras sorbifolia Bunge oil (XSBO) has garnered significant interest from researchers due to its distinctive anti-Alzheimer's disease (AD) properties. However, the underlying molecular mechanism remain unclear. This study aims investigate potential mechanisms by which XSBO may exert therapeutic effects on AD employing a combination of network pharmacology analysis and experimental validation. The chemical composition absorbed compounds were identified using GC-MS LC-MS. Network was...
Spontaneous preterm labor (PTL) accounts for approximately 70% of births, posing significant risks to both maternal and neonatal health. Current predictive biomarkers lack sufficient reliability, underscoring the need non-invasive dependable indicators. Emerging research indicates that tRNA-derived small RNAs (tsRNAs) are involved in various diseases; however, their potential association with PTL remains underexplored. Bioinformatics analyses public GEO datasets (PRJNA415953 PRJNA428989)...
Ketones are among the most useful functional groups in organic synthesis. Here, we report a carbonylative cross-electrophile coupling reaction that utilizes carbon monoxide gas as both carbonyl source and reductant. The use of Pd/Rh cooperative catalysis enables easily accessible aryl triflates bromides. Unlike previous reactions, method does not require addition stoichiometric metal Notably, density theory (DFT) calculations isotope-labeling indicate CO serves
Abstract Anti‐ N ‐methyl‐ d ‐aspartate receptor (anti‐NMDA‐R) encephalitis is an autoimmune disorder that was first described by Dr Vitaliani in 2005. In 2007, Dalmau et al. found anti‐NMDA‐R antibody expressed both the hippocampus and prefrontal nerve cell membrane, finally proposing diagnosis of encephalitis. Most patients are female (91%), with ages ranging from 4 to 76 years. The average age 23 years, a birth peak age, although rare during pregnancy. characterized prominent psychosis,...
Introduction Placenta accreta spectrum (PAS) may cause enormous and potentially life-threatening hemorrhage in the intrapartum postpartum periods emergency cesarean section. How to reduce occurrence of section patients with severe PAS is key reducing adverse outcomes them. This study aimed investigate impact on perioperative pregnant women neonates, also explore risk factors PAS. Materials methods A retrospective investigation was conducted among 163 Of these, 72 were subjected sections....
High-altitude polycythemia (HAPC) is a common chronic altitude disease caused by living in low-pressure and low-oxygen environment. At present, there still no effective cure for HAPC. HIF-2α may play an important role the development of HAPC regulating increased red blood cell excessively induced HIF-EPO vessel formation VEGF-VEGFR. Here, we established rat model treated it with inhibitor PT2385. We mainly evaluated therapeutic effect PT2385 on rats observing changes phenotype, tissue organ...
Combining traditional clinical parameters with neuroendocrine markers to construct a nomogram model predict the postoperative recurrence of carcinoma cervix (NECC).A total 257 patients were included in this study. Univariate and multivariate Cox regression analyses used establish training cohorts, which was further validated validation cohorts. The calibration curve conduct internal external verification model.Overall, 41 relapse cases observed (23 cases) (18 univariate analysis...
Purpose: LncRNA HCP5 has been reported to participate in high glucose-induced pathological processes, whereas its role gestational diabetes mellitus (GDM) is unclear. This study aimed explore the of GDM. Methods: enrolled a total 220 pregnant women (gestational age = 1 month). A follow-up was performed until delivery. The occurrence GDM checked every month during follow-up. Plasma samples were collected from all participants and expression determined with RT-qPCR. patients divided into low...
Panax ginseng, known as the "king of herbs", is a highly valued medicinal plant, and its parts include roots, stems, leaves, flowers, fruits, among which roots are most commonly used. The main active components this plant triterpenoid saponins, polysaccharides, peptides, volatile oils. chemical metabolites endow herb with variety pharmacological effects, thus used to treat various diseases play healthcare roles. Currently, wide range preparations P. ginseng have been officially...
The prenatal detection of placenta accreta spectrum (PAS) disorder is crucial for treatment strategy formulation. MRI descriptors may offer a more objective method predicting PAS and clinical outcomes. aim this study to investigate the predictive value examination intraoperative blood loss in cesarean section elucidating that are valuable loss. A prospective was carried out on 164 pregnant women diagnosed with PAS. Maternal neonatal perioperative characteristics were systematically...
<h3>BACKGROUND AND PURPOSE:</h3> To date, MRS study of both normal and pathologic brains have focused mainly on the supratentorial regions; few studies investigated infratentorial regions. However, pons, an important structure brain, is associated with many neurodegenerative diseases often damaged by brain trauma. For pontine disease, one must obtain reference data metabolite levels in including how these vary age. The aim this was to analyze normal, age-related, metabolic changes pons using...
Accurate and reliable assessment of the conscious state patients with severe traumatic brain injury (TBI) is vital for their future management. The purpose present study to find an effective accurate magnetic resonance imaging (MRI) method predicting recovery consciousness in TBI. Multimodal MR techniques, including structural MRI, spectroscopy (MRS), diffusion tensor (DTI), were used evaluate damage 58 Statistical analysis compared results over a relatively long period most potent...
A nickel-catalyzed cross-electrophile coupling of allylic acetates and gem-difluorovinyl tosylate is presented, which first achieves gem-difluoroolefins via C(sp3)–C(sp2) coupling. In addition, this protocol was performed under mild reaction conditions, affording a variety arenes in moderate to good yields. Moreover, both linear branched acetate could produce cross-coupling product exclusively. Mechanistic studies reveal that the involves two different Ni(0)/Ni(II) catalytic cycles.
Birth defects have brought about major public health problems, and studying the clinical outcomes of most common prenatal central nervous system abnormality, namely, fetal ventriculomegaly (VM), is helpful for improving reproductive fertility quality. This a retrospective cohort study from 2011 to 2020 in West China Second University Hospital, Sichuan University, aiming evaluate short-term long-term VM over 37 weeks' gestation exclude influence preterm birth. The analyzed data 401 term...
This study aims to determine the optimal cut-off value of Ki-67 better predict recurrence early low-risk endometrial cancer (EC).Seven hundred and forty-eight patients diagnosed with EC from West China Second Hospital Sichuan University First Affiliated Chongqing Medical were retrospectively analyzed. The receiver operating characteristic curve (ROC) Youden index used calculate expression. clinicopathological indexes between two groups divided by compared. univariate multivariate regression...