A5040788360- Lipid Membrane Structure and Behavior
- Surfactants and Colloidal Systems
- Supramolecular Self-Assembly in Materials
- Polymer Surface Interaction Studies
- Protein Structure and Dynamics
- Advanced Polymer Synthesis and Characterization
- Proteins in Food Systems
- Advanced biosensing and bioanalysis techniques
- Pickering emulsions and particle stabilization
- RNA Interference and Gene Delivery
- Block Copolymer Self-Assembly
- Quantum, superfluid, helium dynamics
- Force Microscopy Techniques and Applications
- Tardigrade Biology and Ecology
- Enzyme Structure and Function
- Perovskite Materials and Applications
- Luminescence and Fluorescent Materials
- Microencapsulation and Drying Processes
- Coral and Marine Ecosystems Studies
- Marine animal studies overview
- Enzyme Catalysis and Immobilization
- Adipose Tissue and Metabolism
- Nanocluster Synthesis and Applications
- Endoplasmic Reticulum Stress and Disease
- Carbon and Quantum Dots Applications
Max Planck Institute for Polymer Research
2023-2024
Institut Polytechnique de Bordeaux
2021-2023
Université de Bordeaux
2021-2023
Centre National de la Recherche Scientifique
2022-2023
University of Córdoba
2018-2023
Laboratoire de Chimie des Polymères Organiques
2022-2023
Centro Científico Tecnológico - Córdoba
2019
Universidad Complutense de Madrid
2016-2018
Marie Curie
2018
Abstract Stretchable, soft electronics have high potential for wearable healthcare applications and biointerfacing. One approach to render inherently brittle conductive polymers such as poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) stretchable are organic plasticizers. However, little is known on how they affect the morphology in result electrical properties of thin‐films. This study fundamentally explores this relationship using a bilayer model transfer‐printed...
Sugar-based amphiphiles are a relevant natural alternative to synthetic ones due their biodegradable properties. An understanding of structure–assembly relationship is needed allow the concrete synthesis suitable derivatives. Here, four different mannose-derivative surfactants characterized by pendant drop, dynamic light scattering, small-angle X-ray cryotransmission electron microscopy, and molecular dynamics techniques in aqueous media. Measurements denote how polysaccharide average degree...
In this work, monodisperse agarose gel nanoparticles were prepared using a W/O microemulsion as template to control the size of obtained particles. The combination method with temperature-induced gelling and solvent exchange methodology has allowed preparing stable aqueous dispersions in water. average size, measured an apparent hydrodynamic diameter, particles was around 150 nm. ability hydrogel for encapsulation release synthetic insecticide (azamethiphos) tested. results evidence that...
Fmoc-dipeptides are self-assembled at the air/liquid interface as a function of their aminoacid sequence.
This comprehensive review aims to provide a deep insight into the fascinating field of biophysics in living organisms through study model fluid interfaces that mimic specific lipid-based structures with biophysical relevance. By delving these physiological interfaces, we can unravel crucial aspects their behavior, lateral organization, and functions. Through examples, will uncover intricate dynamics at play shed light on potential pathogenic conditions may result from alterations interfaces....
Lipid membranes and proteins, which are part of us throughout our lives, have been studied for decades. However, every year, new discoveries show how little we know about them. In a reader-friendly manner people not involved in the field, this paper tries to serve as bridge between physicists biologists young researchers diving into field its relevance, pointing out just some plethora lines research yet be unraveled. It illustrates ways, from experimental theoretical approaches, needed order...
Abstract Tardigrades are unique micro‐organisms with a high tolerance to desiccation. The protection of their cells against desiccation involves tardigrade‐specific proteins, which include the so‐called cytoplasmic abundant heat soluble (CAHS) proteins. As first step towards design peptides capable mimicking cytoprotective properties CAHS we have synthesized several model sequences selected from conserved motifs and investigated what extent they exhibit desiccation‐induced structural changes...
Macromolecular crowding agents, such as poly(ethylene glycol) (PEG), are often used to mimic cellular cytoplasm in protein assembly studies. Despite the perception that agents have an inert nature, we demonstrate and quantitatively explore diverse effects of PEG on phase separation maturation condensates. We use two model proteins, FG domain Nup98 bovine serum albumin (BSA), which represent intrinsically disordered a with well-established secondary structure, respectively. expedites Nup98,...
Abstract Fluorescent nanoparticles, such as quantum dots, hold great potential for biomedical applications, mainly sensing and bioimaging. However, the inefficient cell uptake of some nanoparticles hampers their application in clinical practice. Here, effect modification dot surface with fluorinated ligands to increase activity and, thus, enhance cellular was explored.
Fmoc-dipeptides appear as highly relevant building blocks in smart hydrogels and nanovehicles for biological applications. The interactions of the with cell membrane determine efficiency nanomaterials based on Fmoc-dipeptides' internalization drug delivery. Here, we aim to understand interplay between a phospholipid surface function amino acid sequence. DMPA (1,2-dimyristoyl-sn-glycero-3-phosphate) Langmuir monolayers was used model surface. A set seven derivatives broad range hydrophobicity...
Mechanical and morphological effects of monolayers octadecylamine upon aspirin adsorption are monitored by Langmuir isotherms measurements Brewster angle microscopy. Aspirin induced a notable expansion the corresponding concentration-dependence mechanical stability films as consequence subtle balance between solubility amine monolayer stabilization ion-pairs, corroborated Angle Microscopy images. The incorporation into interface was confirmed UV–vis reflection spectroscopy. Some comments on...
Abstract A common approach to enhance the stability of metal halide perovskites (MHPs) implemented in optical and optoelectronic devices is incorporate polymer additives into perovskite layer. β ‐(1,4) cellulose oligosaccharide (COS) synthesized by mechanocatalytic depolymerization has been incorporated films BA 2 MA 4 Pb 5 I 16 (BA = n ‐butylammonium methylammonium) two‐dimensional (2D) Ruddlesden‐Popper (RP) hybrid perovskite. Scanning Electron Microscopy (SEM) images displayed a...
Abstract Nanostructured block copolymer (BCP) thin films enable the formation on‐demand of a variety periodic patterns at nanometer scale by tuning macromolecular BCP characteristics and annealing processes. Significant progress in control self‐assembly has been witnessed over past decade with implementation robust directed methods. However, self‐assembled structural obtained equilibrium are limited methods to expand range configurations required harness additional functionalities. Here,...
Amino acids including the Fmoc group (9-fluorenylmethyloxycarbonyl) are bioinspired molecules that display intriguing features in self-assembly and biological applications. The influence of a delicate chemical modification between Fmoc-F Fmoc-Y on interaction with phospholipid surface was analyzed. Langmuir monolayers 1,2-dimyristoyl-sn-glycero-3-phosphate (DMPA) were used to mimic eukaryotic cell membrane. In situ Brewster angle microscopy UV-vis reflection spectroscopy provided insights...
Block copolymer (BCP) self-assembly in thin films is an elegant method to generate nanometric features with tunable geometrical configurations. By combining directed assembly and hybridization methods, advances nano-manufacturing have been attested over the past decades flagship applications lithography optics. Nevertheless, range of configurations limited by accessible morphologies inherent energy minimization process involved BCP self-assembly. Layering nanostructured has recently proposed...
Abstract Fluid interfaces provide an advanced platform for directed self‐assembly of organic composites and formation supramolecular polymers (SPs). Intermolecular interactions govern the polymerization processes, with hydrogen bonding (H‐bonding) as a key interaction in chemistry biology. Two purposefully designed supra‐amphiphiles assessing role H‐bonding were their (SP) at air/water interface was compared. confirmed by situ experimental computational techniques required intermolecular...
ABSTRACT Tardigrades are unique micro-animals that withstand harsh conditions, such as extreme temperatures and desiccation. Recently, it was found specific cytoprotective proteins essential for ensuring this high environmental tolerance. In particular, cytoplasmic abundant heat soluble (CAHS) proteins, which intrinsically disordered, adopt more ordered conformations upon desiccation, involved in the vitrification of cytoplasm. The design synthesis short peptides capable mimicking structural...
ABSTRACT Crowding agents, such as polyethylene glycol (PEG, are often used to mimic the cellular cytoplasm in protein assembly studies. Despite perception that crowding agents have an inert nature, recent work has shown they not bystanders while proteins interact. Here, we explore diverse effects of PEG on phase separation and maturation proteins. We use two proteins, FG domain Nup98 bovine serum albumin (BSA), which represent intrinsically disordered a with well-established secondary...