- Viral gastroenteritis research and epidemiology
- Orthopedic Infections and Treatments
- COVID-19 Clinical Research Studies
- Orthopaedic implants and arthroplasty
- Diagnosis and treatment of tuberculosis
- Viral Infections and Immunology Research
- Tuberculosis Research and Epidemiology
- COVID-19 and healthcare impacts
- Congenital Anomalies and Fetal Surgery
- Animal Virus Infections Studies
- Antimicrobial Resistance in Staphylococcus
- Pancreatitis Pathology and Treatment
- Diabetes Treatment and Management
- Bacterial Identification and Susceptibility Testing
- Hepatitis Viruses Studies and Epidemiology
- COVID-19 epidemiological studies
- Diabetes and associated disorders
- Infective Endocarditis Diagnosis and Management
- Sepsis Diagnosis and Treatment
- Agriculture and Farm Safety
- Dialysis and Renal Disease Management
- Total Knee Arthroplasty Outcomes
- Metabolism, Diabetes, and Cancer
- Vascular Procedures and Complications
- Clinical Laboratory Practices and Quality Control
University Hospital of Wales
2025
Public Health Wales
2025
Mater Misericordiae University Hospital
2022-2024
Beaumont Hospital
2020-2024
Royal College of Surgeons in Ireland
2020-2024
Our Lady of Lourdes Hospital
2024
Munster Technological University
2005-2014
Abstract Septic arthritis is a serious condition with significant morbidity and mortality, routinely diagnosed using culture. The FDA has recently approved the rapid molecular BioFire® Joint Infection Panel (BJIP) for synovial fluid. We aimed to evaluate BJIP compared culture its potential use in patient management. A multicentre retrospective evaluation of was conducted UK Ireland. Positive percent agreement (PPA) negative (NPA) were calculated between routine multidisciplinary team (MDT)...
: The BIOFIRE Joint Infection (JI) Panel is a diagnostic tool that uses multiplex-PCR testing to detect microorganisms in synovial fluid specimens from patients suspected of having septic arthritis (SA) on native joints or prosthetic joint infections (PJIs).
Introduction: Gram stain of synovial fluid is a rapid test for the diagnosis native joint septic arthritis. Single-centre studies have suggested will miss considerable proportion patients who are subsequently synovial-fluid-culture-positive or polymerase chain reaction (PCR)-positive. The object this study was to reassess in large, multi-centre cohort from United Kingdom (UK) and Ireland. Methods: retrospective analysis combining two large datasets. We defined arthritis microbiologically as...
Two hundred and thirty fecal specimens were collected from children (up to 5 years of age) admitted with suspected rotaviral gastroenteritis at four Irish hospitals (Cork University Hospital, Mercy Cork, Waterford Regional Kerry General Hospital) in the southern region Ireland, between 2001 2004. Following laboratory confirmation aetiological agent, rotavirus G-type was determined all positive samples by reverse transcriptase-polymerase chain reaction (RT-PCR). The distribution G-types (n =...
Abstract Six hundred and thirty three fecal specimens were collected from patients under 6 years, suffering non‐bacterial, putative viral gastroenteritis in the south of Ireland, between 2003 2006. Following laboratory identification rotavirus as aetiological agent 558 specimens, reverse transcriptase polymerase chain reaction was employed to amplify VP7 VP4 gene segments 249 245 samples, respectively. G P typing subsequently carried out on these amplicons. G1 (65.1%), G3 (16.1%) found be...
<ns3:p>Sodium-glucose cotransporter-2 (SGLT2) inhibitors are filtered and secreted to their primary site of action in the proximal tubule kidney. At this site, SGLT2 also reduce renal elimination ketone bodies, a finding implicated propensity cause ketoacidosis. Many commonly used medications have potential diminish compound effects on bodies by inhibiting tubular secretion inhibitor itself and/or bodies. We present case severe diabetic ketoacidosis (DKA) patient with type 2 diabetes...
Tuberculosis (TB) elimination requires high-quality, timely care. In countries with a low incidence of TB, such as Ireland, delayed diagnosis is common. This evaluation aimed to determine the factors that predict patient-related and health care provider-related delays in TB management establish how cost affected by delays. Health records patients signs symptoms evaluated tertiary service Ireland between July 1, 2018, December 31, 2019, were reviewed measure predictors delays, Outcomes...
<ns3:p>Sodium-glucose cotransporter-2 (SGLT2) inhibitors are filtered and secreted to their primary site of action in the proximal tubule kidney. Many commonly used medications have potential diminish renal elimination SGLT2 by inhibiting tubular secretion. We present a case severe diabetic ketoacidosis (DKA) patient with type 2 diabetes occurring several days after co-prescription empagliflozin probenecid. Other than recent introduction empagliflozin, no cause for DKA episode was apparent....
Abstract Background Tuberculosis elimination (TB) is a global priority that requires high-quality timely care to be achieved. In low TB incidence countries such as Ireland, delayed diagnosis common. Despite cost being central policy making, it not known if affects among patients in low-incidence setting. Methods Health records of with signs and symptoms evaluated by tertiary service Ireland between July 1st 2018 December 31st 2019 were reviewed measure determine predictors patient-related...