James H. Segars

ORCID: 0000-0001-5969-376X
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About
Contact & Profiles
Research Areas
  • Uterine Myomas and Treatments
  • Endometriosis Research and Treatment
  • Reproductive Biology and Fertility
  • Ovarian function and disorders
  • Assisted Reproductive Technology and Twin Pregnancy
  • Gynecological conditions and treatments
  • Reproductive Health and Technologies
  • Estrogen and related hormone effects
  • Reproductive System and Pregnancy
  • Prenatal Screening and Diagnostics
  • Ovarian cancer diagnosis and treatment
  • Ectopic Pregnancy Diagnosis and Management
  • Endometrial and Cervical Cancer Treatments
  • Retinoids in leukemia and cellular processes
  • Hemostasis and retained surgical items
  • Reproductive Health and Contraception
  • COVID-19 Impact on Reproduction
  • Pregnancy-related medical research
  • Pregnancy and preeclampsia studies
  • Sperm and Testicular Function
  • Birth, Development, and Health
  • Renal and related cancers
  • Cellular Mechanics and Interactions
  • Cytokine Signaling Pathways and Interactions
  • Hypothalamic control of reproductive hormones

Johns Hopkins Medicine
2016-2025

Johns Hopkins University
2016-2025

University Medical Center
2020-2024

University of Tennessee Health Science Center
2022

University College Dublin
2022

Johns Hopkins Hospital
2017-2021

St. Louis Children's Hospital
2021

National Institutes of Health
2009-2020

Eunice Kennedy Shriver National Institute of Child Health and Human Development
2010-2020

RELX Group (United States)
2020

BACKGROUNDUterine fibroids are the most common gynecologic tumors in women of reproductive age yet etiology and pathogenesis these lesions remain poorly understood. Age, African ancestry, nulliparity obesity have been identified as predisposing factors for uterine fibroids. Symptomatic can cause excessive bleeding, bladder dysfunction pelvic pain, well associated disorders such infertility, miscarriage other adverse pregnancy outcomes. Currently, there limited noninvasive therapies no early...

10.1093/humupd/dmt058 article EN public-domain Human Reproduction Update 2014-01-08

A similar abstract of the interim analysis was previously published in Fertility and Sterility. EPIGALLOCATECHIN GALLATE (EGCG) FOR TREATMENT OF UNEXPLAINED INFERTILITY ASSOCIATED WITH UTERINE FIBROIDS (PRE-FRIEND TRIAL): EARLY SAFETY ASSESSMENT. Uterine fibroids are most common cause unexplained infertility reproductive-aged women. Epigallocatechin gallate (EGCG), a green tea catechin, has demonstrated its ability to shrink uterine prior preclinical clinical studies. Hence, we developed an...

10.3390/nu15020320 article EN Nutrients 2023-01-09
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