A5025993925- Metabolomics and Mass Spectrometry Studies
- Ginseng Biological Effects and Applications
- Natural product bioactivities and synthesis
- Pharmacological Effects of Natural Compounds
- Traditional Chinese Medicine Analysis
- Natural Antidiabetic Agents Studies
- Plant-based Medicinal Research
- Tryptophan and brain disorders
- Alzheimer's disease research and treatments
- Cancer Mechanisms and Therapy
- Traditional Chinese Medicine Studies
- Chronic Myeloid Leukemia Treatments
- Membrane Separation Technologies
- Tea Polyphenols and Effects
- Outsourcing and Supply Chain Management
- Phytochemicals and Antioxidant Activities
- Aluminum Alloy Microstructure Properties
- Chronic Lymphocytic Leukemia Research
- Advanced Sensor and Energy Harvesting Materials
- High-Temperature Coating Behaviors
- Diet, Metabolism, and Disease
- Food Quality and Safety Studies
- Gout, Hyperuricemia, Uric Acid
- Knowledge Management and Sharing
- Plant-derived Lignans Synthesis and Bioactivity
Jilin University
2015-2024
Chinese PLA General Hospital
2022-2024
Tea Research Institute
2023-2024
Guizhou Academy of Agricultural Sciences
2023-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2023
University of California, Irvine
2014-2023
North China University of Water Resources and Electric Power
2019-2023
Center for Global Health
2021
Jilin Medical University
2014-2021
Yanshan University
2021
Poly(vinylidene fluoride) (PVDF) powder is graft polymerized with N,N-dimethylacrylamide (DMAA) by a pre-irradiation induced polymerization technique. The existence of the chains in grafted PVDF (PVDF-g-PDMAA) has been proven FT-IR spectroscopy and X-ray Photoelectron Spectroscopy (XPS) analysis. Then, microfiltration (MF) membranes are prepared isothermal immersion precipitation from PVDF-g-PDMAA 1-methyl-2-pyrrolidone (NMP) solution water bath. hydrophilicity MF determined measuring...
This study was designed to investigate the antagonism of SCP in Aβ25–35-induced AD rats by intervening neurotransmitters and metabolites.
Therapeutic effects and potential mechanism of action homogeneous polysaccharide SCP2 on AD rats.
In this paper, orally nanocrystal capsules were produced using formulations in order to optimize dissolution properties of poorly soluble drug glimepiride and improve its bioavailability. The important preparation variables, such as stabilizers, the power input time length ultrasonication on mean particle size polydispersity index investigated systematically, optimal values 0.2% (w/v), 1.2% Lipoid S100, 0.6% PEG 6000 PVPK 30 500 W 2 min, respectively. Characterization was carried out by...
<h3>Objective</h3> To construct a polygenic risk score (PRS) for stroke and evaluate its utility in stratification primary prevention stroke. <h3>Methods</h3> Using meta-analytic approach large genome-wide association results stroke-related traits East Asians, we generated combined PRS (metaPRS) by incorporating 534 genetic variants training set of 2,872 patients with 2,494 controls. We then validated incident using Cox regression models Chinese population-based prospective cohorts...
To investigate the correlation between difference of secondary metabolites and disease-resistance activity different varieties Congou black tea. Among a total 657 identified, 183 had anti-disease activity, 113 were key active ingredients in traditional Chinese medicine (TCM), 73.22% multiple activities, all mainly flavonoids phenolic acids. The main enriched metabolic pathways phenylpropanoid biosynthesis, biosynthesis metabolites, flavonoid pathways. Flavonoid acid more correlated with TCM...
Trk receptor tyrosine kinases have been implicated in cancer and pain. A crystal structure of TrkA with AZ-23 (1a) was obtained, scaffold hopping resulted two 5/6-bicyclic series comprising either imidazo[4,5-b]pyridines or purines. Further optimization these fusion led to compounds subnanomolar potencies against kinase cellular assays. Antitumor effects a TrkA-driven mouse allograft model were demonstrated 2d 3a.
<italic>Schisandra chinensis</italic> (Turcz.) Baill (<italic>S. chinensis</italic>), a functional food, is used as tonic and sedative agent in traditional Chinese medicine.