A5038448811- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Parathyroid Disorders and Treatments
- Head and Neck Anomalies
- BRCA gene mutations in cancer
- Pituitary Gland Disorders and Treatments
- Genetic Syndromes and Imprinting
- Thyroid Disorders and Treatments
- Medical Imaging and Pathology Studies
- Neuroendocrine Tumor Research Advances
- Nutrition, Genetics, and Disease
- Global Cancer Incidence and Screening
- Cardiac, Anesthesia and Surgical Outcomes
- History of Medical Practice
- Diversity and Career in Medicine
- Radiation Dose and Imaging
- Genetic factors in colorectal cancer
- Pancreatic and Hepatic Oncology Research
- Telomeres, Telomerase, and Senescence
- Cancer Diagnosis and Treatment
- Toxic Organic Pollutants Impact
- Innovations in Medical Education
- Adrenal and Paraganglionic Tumors
- Health and Medical Research Impacts
- Genetics, Bioinformatics, and Biomedical Research
Baptist Hospital of Miami
2024
Miami Heart Research Institute
2019-2023
Miami Transplant Institute
2017-2022
Yale University
2008-2019
Florida International University
2019
Yale New Haven Hospital
2003-2018
Yale Cancer Center
2015-2017
Baptist Health South Florida
2017
Islamic Azad University of Tabriz
2016
University School
2013
The incidence of thyroid cancer has increased at an alarming rate in both men and women the United States. etiology this epidemic is unclear. We tested hypothesis that a significant component due to detection occult disease. examined whether density endocrinologists general surgeons as well employment cervical ultrasonography were factors associated with epidemic.Thyroid rates by states obtained from States Cancer Statistics 1999-2009 reported National Program Registries. densities...
abstract A 1991 NIH Consensus Development Conference statement provided recommendations for the management of patients with asymptomatic and minimally symptomatic primary hyperparathyroidism (1° HPT), but adherence to these guidelines has not been documented. We conducted a cross-sectional survey North American members Association Endocrine Surgeons inquiring about surgeon 1° HPT patient characteristics, thresholds surgery, clinical outcomes. Multivariate regression was used assess...
Follicular epithelial cell-derived thyroid tumors are common neoplasms comprised mainly of benign adenomas, follicular cancers, and papillary cancers (PTCs). Hypermethylation the tumor suppressor gene RASSF1A activating mutation BRAF have been reported recently in cancers. To additionally investigate roles these two epigenetic/genetic alterations progression, we examined their occurrences relationship both malignant neoplasms. With real-time quantitative methylation-specific PCR, found that...
Abstract The Bethesda 2007 Thyroid Cytology Classification defines follicular lesion of undetermined significance as a heterogeneous category cases that are not convincingly benign nor sufficiently atypical for diagnosis neoplasm or suspicious malignancy. In our institution, we refer to these indeterminate, and they further sub‐classified into two: (1) low cellularity with predominant microfollicular architecture absence colloid (IN ) (2) nuclear features characteristic lesions (nuclear...
Thyroid cancers have increased dramatically over the past few decades. Comorbidities may be important, and previous studies indicated elevated second cancer risk after initial primary thyroid cancers. This study examined of development a cancer, utilizing Surveillance, Epidemiology, End Results (SEER) program database.The cohort consisted men women diagnosed with first who were reported to SEER database in 1973-2008 (n=52,103). Standardized incidence ratios (SIR) calculated for all secondary...
Background: The effects of thyroid-stimulating hormone (TSH) and thyroid hormones on the development human papillary cancer (PTC) remain poorly understood.Methods: study population consisted 741 (341 women, 400 men) histologically confirmed PTC cases matched controls with prediagnostic serum samples stored in Department Defense Serum Repository. Concentrations TSH, total T3, T4, free T4 were measured samples. Conditional logistic regression models used to calculate ORs 95% confidence...
Although the frozen section is widely used to identify tissue type during parathyroid exploration in patients with hyperparathyroidism, questions regarding its accuracy have been raised. Frozen error has identified as a significant factor contributing surgical failure. The purpose of this study was establish setting and pitfalls underlying error. final pathologic diagnoses were compared paired for all who underwent at institution period between 1984 1997. For those cases which discrepancy...
To evaluate the short- and long-term consequences of palliative reresection specific symptomatic lesions in patients with widely disseminated (incurable) medullary thyroid cancer (MTC).Although reoperative neck microdissections can normalize calcitonin levels metastatic MTC confined to regional lymph nodes, there is no curative therapy for disease. However, these frequently have prolonged survival, but often debilitating symptoms.Between October 1981 January 1997, 16 (mean age, 46 +/- 3...
Thyroid cancer incidence and diagnostic radiography exposures, particularly computed tomography (CT) scanning nuclear medicine examinations, have increased substantially in the USA. However, very few epidemiologic studies directly investigated their associations. A population-based case-control study was conducted Connecticut 2010-2011, including 462 histologically confirmed incident thyroid cases 498 controls. Multivariate unconditional logistic regression models were used to estimate...
Background: The BRAF V600E mutation has been reported in 50%–80% of papillary thyroid carcinoma (PTC) cases and is highly specific for PTC. Reflex testing may improve the diagnostic accuracy fine-needle aspiration (FNA) tests having equivocal cytologic interpretations provide prognostic information that helps guide management patients with Patients Methods: Cases FNA readings (indeterminate suspicious PTC) or a positive diagnosis PTC concomitant analysis were included this prospective study....