- Nerve injury and regeneration
- Spinal Cord Injury Research
- Tendon Structure and Treatment
- Medicinal Plants and Bioactive Compounds
- Soft tissue tumor case studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Sarcoma Diagnosis and Treatment
- Optimism, Hope, and Well-being
- Oral and Maxillofacial Pathology
- Erythropoietin and Anemia Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Elbow and Forearm Trauma Treatment
- Bone Tumor Diagnosis and Treatments
- Adenosine and Purinergic Signaling
- Genomics, phytochemicals, and oxidative stress
- Musculoskeletal synovial abnormalities and treatments
- Oral and gingival health research
- Cancer-related molecular mechanisms research
- Neurofibromatosis and Schwannoma Cases
- Ear and Head Tumors
- Inflammasome and immune disorders
- IL-33, ST2, and ILC Pathways
- Dysphagia Assessment and Management
- Cancer Diagnosis and Treatment
- Lymphadenopathy Diagnosis and Analysis
Shanghai Pulmonary Hospital
2015-2025
Tongji University
2015-2025
Jinzhou Medical University
2023
Shenzhen Children's Hospital
2017-2022
Peking University Shenzhen Hospital
2016-2017
Peking University
2015
Nanjing Drum Tower Hospital
2010-2014
Bengbu Medical College
2014
Nanjing University
2011
San Francisco VA Medical Center
1998
With the development of functional genomics studies, a mass long non-coding RNAs (LncRNA) were discovered from human genome. Long serve as pivotal regulators genes that are able to generate LncRNA-binding protein complexes modulate great number genes. Recently, LncRNA urothelial carcinoma-associated 1 (UCA1) has been revealed be dysregulated, which plays critical role in few cancers. However, biology and clinical significance UCA1 tumorigenesis oral squamous cell carcinoma (OSCC) remain...
Introduction: To investigate how adipose-derived mesenchymal stem cells (ADSCs) regulate the balance between regulatory T (Treg) and Th17 through IL-2/JAK3/STAT5 signaling pathway in a rat model of allergic rhinitis (AR). Methods: Adipose-derived were used to treat an ovalbumin (OVA)-induced AR model. The pathological changes nasal symptoms observed by HE staining scanning electron microscopy. concentrations OVA-sIgE, IL-10, IL-17 serum measured enzyme-linked immunosorbent assay (ELISA)....
Objective: To investigate the effects of sampling methods on pathological assessment resected non-small cell lung cancer (NSCLC) specimen with tumor maximum diameter >3 cm after neoadjuvant therapy. Methods: NSCLC patients a large (diameter cm) that were therapy from June 2020 to July 2023 retrospectively collected in Department Pathology, Shanghai Pulmonary Hospital, Shanghai, China. Sampling bed performed accordance international and Chinese experts recommendations for resection specimens...
Malignant gastrointestinal neuroectodermal tumor (GNET) is a rare soft tissue sarcoma, previously referred to as clear cell sarcoma‑like (CCSLGT) and also commonly reported in the literature sarcoma of tract (CCS‑GI). The current study reports case GNET arising stomach 17‑year‑old male, who presented with symptoms fatigue, anemia low temperature. Examination positron emission tomography‑computed tomography revealed mass gastric antrum. Subsequently, radical distal resection was performed,...
To analyze the relationship between position of embedded mesiodens in maxilla and surgical approach children thus provide reference materials for design.According to preoperative cone-beam computed tomography (CBCT) examination, location characteristics 625 aged 4-16 years old who presented with were diagnosed our department from January 2016 December 2021 statistically analyzed.There 877 children. The selected cases classified according axial angle adjacent normal teeth or tooth germs,...
In our previous studies, antioxidant transcription factor, nuclear factor erythroid 2-related 2 (Nrf2) signaling pathway has been shown to play an important role in protecting traumatic brain injury (TBI)-induced acute lung (ALI). This study was designed explore whether recombinant human erythropoietin (rhEPO) administration modulates pulmonary Nrf2 a murine TBI model.Closed head made by Hall's weight-dropping method. The rhEPO administered at dose of 5,000 IU/kg 30 minutes after TBI....
Diffuse‑type tenosynovial giant cell tumor (D‑GCTS) is a rare benign lesion that not only frequently occurs in the fingers, but also along tendon sheaths of foot and ankle. The present study reports cases two middle‑aged patients were diagnosed with D‑GCTS. presentation D‑GCTS lesions was extremely rare, as tumors located temporal fossa threatened skull base external auditory canal. There similarities differences between their clinical symptoms, disease progressions invading sites. patients'...
The purpose of the present article was to describe diagnostic evaluation of, and surgical approaches to, lateral skull base tumors (LSBTs). study is a retrospective review 21 patients diagnosed with that involve (8 malignant diseases 13 benign lesions) who were surgically treated during 8‑year period. transparotid‑transmandibular (38%) most commonly performed procedure, followed by transmandibular (24%), transmaxillary transcervical approach (10%) combined (4%). procedures uneventful there...
YM155, a small molecule inhibitor of survivin, has been studied in many tumors. It shown that YM155 inhibited oral squamous cell carcinoma through promoting apoptosis and autophagy inhibiting proliferation. was found also the carcinoma–mediated angiogenesis inactivation mammalian target rapamycin pathway. Rapamycin, inhibitor, played an important role proliferation lines. In our study, assay, transwell tube formation western blot assay were used to investigate synergistic effect on...
Abstract Background Solitaire AB stent was approved for mechanical thrombectomy acute cerebral infarction. Objectives To present our initial experience regarding the efficacy and safety of using device treatment limb ischemia (ALI). Patients methods 17 consecutive patients presenting with underwent endovascular therapy device. Immediate angiographic results early clinical outcomes are presented. Results Technical success achieved in 15 (88.2%).Recanalization more than IIb on TILI scale...
Objective To discuss the clinical symptoms of severe traumatic cerebral injury patients with paroxysmal sympathetic hyperactivity (PSH). These were given positive and effective prevention treatment to reduce complications in order improve prognosis. Methods Twenty PSH selected from October 2010 2014 analyzed by gender, age, diagnosis, symptoms, laboratory equipment inspection summary experiences such patients. Results Of 20 patients,14 males 6 females,with age 22-65 (35.4 ± 9.5)...