Ethan J. Pappas

ORCID: 0000-0001-6139-8532
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About
Contact & Profiles
Research Areas
  • Viral Infections and Outbreaks Research
  • Hepatitis B Virus Studies
  • COVID-19 epidemiological studies
  • Infection Control in Healthcare
  • Infection Control and Ventilation
  • Medical Device Sterilization and Disinfection

Purdue University West Lafayette
2022

Cleveland Clinic
2020

Ebola virus (EBOV) infections continue to pose a global public health threat, with high mortality rates and sporadic outbreaks in Central Western Africa. A quantitative understanding of the key processes driving EBOV assembly budding could provide valuable insights inform drug development. Here, we use computational model evaluate matrix assembly. Our focuses on kinetics VP40, protein EBOV, its interaction phosphatidylserine (PS) host cell membrane. It has been shown that mammalian cells...

10.1016/j.jbc.2022.102025 article EN cc-by Journal of Biological Chemistry 2022-05-11

Abstract Ebola virus (EBOV) infections continue to pose a global public health threat, with high mortality rates and sporadic outbreaks in Central Western Africa. A quantitative understanding of the key processes driving EBOV assembly budding could provide valuable insights inform drug development. Here we used computational model evaluate matrix assembly. Our focused on kinetics VP40, protein EBOV, its interaction phosphatidylserine (PS) host cell membrane. Human cells transfected...

10.1101/2021.07.22.453424 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-07-25
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