A5011076291- Effects and risks of endocrine disrupting chemicals
- Toxic Organic Pollutants Impact
- Analytical Chemistry and Chromatography
- Food Quality and Safety Studies
- Fermentation and Sensory Analysis
- Pharmacological Effects and Assays
- Meat and Animal Product Quality
- Heavy metals in environment
- Analytical chemistry methods development
- Heavy Metals in Plants
- Advanced Chemical Sensor Technologies
- Mercury impact and mitigation studies
- Chemical Analysis and Environmental Impact
- Heavy Metal Exposure and Toxicity
- Mass Spectrometry Techniques and Applications
- Pesticide Residue Analysis and Safety
- Mycotoxins in Agriculture and Food
- Marine Toxins and Detection Methods
- Carcinogens and Genotoxicity Assessment
- Dye analysis and toxicity
- Tea Polyphenols and Effects
- Aquatic Ecosystems and Phytoplankton Dynamics
- Pharmaceutical and Antibiotic Environmental Impacts
- Listeria monocytogenes in Food Safety
- Anesthesia and Neurotoxicity Research
Zhejiang Center for Disease Control and Prevention
2015-2024
Centers for Disease Control and Prevention
2012-2014
Hangzhou Xixi hospital
2014
Environmental pollution with toxic heavy metals can lead to the possible contamination of rice. Selected (As, Cd, Hg and Pb) their accumulation in rice collected from Zhejiang, China were analyzed evaluate potential health risk local adults children. The mean levels found as follows: As, 0.080 mg/kg; 0.037 Hg, 0.005 Pb, 0.060 mg/kg. estimated daily intakes (EDIs) calculated combination consumption data. Pb through be 0.49, 0.23, 0.03 0.37 µg/kg bw/day for adults, 0.34, 0.29, 0.04 0.47 97.5th...
The present study analyzed 5785 vegetables for concentrations of As, Cd, Cr, Pb, Ni and Hg, estimated the health risk to local consumers by deterministic (point estimates) approaches. Levels elements varied in different vegetables. Average levels Ni, Hg Pb were 0.013, 0.017, 0.057, 0.002, 0.094 0.034 mg/kg (fresh weight), respectively. samples with 0.25% Cd 1.56% exceeding maximum allowable (MACs) set Chinese Health Ministry. No obvious regular geographical distribution these metals was...
A total of 139 vegetable oils and 48 frying produced in China were tested for the levels 15 Environmental Protection Agency-regulated polycyclic aromatic hydrocarbons (PAHs). The analysis was completed by high-performance liquid chromatography-fluorescence detection (HPLC-FLD). limit quantitation ranged between 0.2-0.3 0.6-1 μg/kg, respectively. average recovery 58.6-90.6%. highest mean PAHs found peanut oil (3.31 μg/kg), while lowest content olive (0.39 μg/kg). In brief, 32.4% exceeded...
The purpose of this study was to assess the risk aflatoxins due multiple food consumption among Zhejiang population. Ultra-high-performance liquid chromatography coupled with tandem mass spectrometry method used determine in 792 samples. Aflatoxins were detected 27.1% samples at levels between 0.07 and 262.63 μg kg-1, B1 most frequently different types 0.8% peanut oil, 3.39% nut products as well 1.1% condiments contaminated exceeded China national tolerance limits. Peanut oil had highest...
A quantified method for the determination of 17 phthalate esters ( PAE s) in edible vegetable oil by GC ‐ MS with pretreatment acetonitrile extraction and silica/ N ‐( n P ropyl)ethylenediamine‐mixed SPE column was established. By quantification internal standard D 4 d i(2‐ethylhexyl) phthalate, a good linearity range related s observed. The correlation coefficient ranged at 0.994∼1.000, lowest level 0.05∼0.15 mg/L. spiking recoveries were 78.3∼108.9% relative deviations 4.3∼12.1% = 6)....
Abstract The objective of this study was to establish a method for detecting fatty acid esters chloropropanols [including 2-monochloropropane-1,3-diol (2-MCPD) ester and 3-monochloropropane-1,2-diol (3-MCPD) ester] in infant milk powder using isotope dilution GC-MS. fat fraction samples extracted treated with sodium methylate–methanol cleave the bonds 2- 3-MCPD esters. resultant 3-MCPDs were purified matrix solid-phase liquid–liquid extraction derivatized heptafluorobutyryl imidazole GC-MS...
Matrix-dependent signal suppression often occurs in quantitative analysis by ultra-high pressure liquid chromatography tandem mass spectrometry (UPLC-MS/MS). In this study, we investigated three calibration methods for compensation of on chloramphenicol (CAP) quantification chicken muscle. The data showed that the spiking recoveries solvent standard with a stable isotope labelled internal (SIL-IS) and matrix-matched SIL-IS were significantly higher than external (P < 0.05). When was used,...
Both gas chromatography-mass spectrometry in electron ionization (GC-MS-EI) and negative chemical (GC-MS-NCI) modes are reported this paper for the simultaneous determination of 1,3-dichloropropan-2-ol (1,3-DCP), 2,3-dichloropropan-1-ol (2,3-DCP), 3-chloropropane-1,2-diol (3-MCPD) 2-chloropropane-1,3-diol (2-MCPD) soy sauce other flavoring. D(5)-3-MCPD (for 3-MCPD 2-MCPD) d(5)-1,3-DCP 1,3-DCP 2,3-DCP) were used as deuterium isotopic labelled internal standards. The feasibility using...
By the combination of solid‐phase extraction as well isotope dilution gas chromatography with mass spectrometry, a sensitive and reliable method for determination endocrine‐disrupting chemicals including bisphenol A, 4‐octylphenol, 4‐nonylphenol in vegetable oils was established. The application silica/ N ‐( n ‐propyl)ethylenediamine mixed cartridge achieved relatively low matrix effects oils. Experiments were designed to evaluate derivatization, parameters optimized. estimated limits...
Background: Phthalates have been blended in various compositions as plasticizers worldwide for a variety of purposes, and there are more polymers the packaging tobacco.Methods: We investigated phthalate exposure pregnant women to explore influence environmental tobacco smoke (ETS). In 2013, total 620 30 counties (district) Zhejiang Province were selected by probability proportionate size sampling method, they interviewed sociodemographic characteristic, lifestyle characteristics, 77 them...
The concentration of methylmercury (MMC) and total mercury (TMC) in marine fishes (five species) frequently consumed the coastal areas Zhejiang province, China, was determined. method high-performance liquid chromatography-atomic fluorescence spectrometry (HPLC-AFS) with microwave-assisted extraction used for MMC determination. TMC analysed by a direct analyser. concentrations five fish species ranged from 53 to 158 µg kg⁻¹ 60 172 kg⁻¹, respectively. proportion levels greater than 80%....
A detection method for 19 kinds of phthalic acid ester compounds analyzed by n-hexane/ether/acetonitrile 1:7:8 v/v/v mixed solvent extraction, quick, easy, cheap, effective, rugged, and safe purification internal standard quantitative gas chromatography with mass spectrometry was established. This can effectively remove interfering materials, such as lipids, fatty acids, pigments, from dairy products. The were within a 0.025-0.2 mg/kg range, the recovery rate 65.2-125.7%, relative deviation...
A gas chromatography-mass spectroscopy (GC-MS) method was developed to assess the infant exposure assessment from four important polycyclic aromatic hydrocarbon (PAH) markers in formula powder: benzo[a]anthracene, chrysene, benzo[b]fluoranthene, and benzo[a]pyrene (collectively referred as PAH4). The required addition of an isotopically labeled internal standard, sample extraction under alkali conditions, a saponification step, solid-phase purification step. In controlled spike test, average...
β2-agonists are a class of synthetic sympathomimetic drugs with acute poisoning effects if consumed as residues in foods. To improve the efficiency sample preparation and to overcome matrix-dependent signal suppression quantitative analysis four (clenbuterol, ractopamine, salbutamol, terbutaline) fermented ham, an enzyme digestion coupled cation exchange purification method for was established using ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS)....
The intake of paralytic shellfish toxins (PSTs) may adversely affect human health. Therefore, this study aimed to show the prevalence PSTs from commercially available in Zhejiang Province, China, during period frequent red tides, investigate factors affecting distribution PSTs, and assess risk PST following consumption bivalve among population. A total 546 samples were collected, 7.0% which had detectable at concentrations below regulatory limit. Temporal, spatial, interspecific variations...
The four polycyclic aromatic hydrocarbon markers (PAH4) of benzo[a]anthracene (BaA), chrysene (Chr), benzo[b]fluoranthene (BbF), and benzo[a]pyrene (BaP) are indicators showing (PAH) contamination levels in Chinese medicine raw materials (CMRMs), extracts health food products; Samples herbal medicine, extracts, supplements were extracted with n-hexane, then cleaned up sequentially on Florisil EUPAH solid-phase extraction (SPE) columns. A gas chromatography-mass spectrometry method for the...
Deoxynivalenol (DON) together with its acetylated derivatives cause detrimental effects on human health, and the purpose of this study was to assess prevalence DON from grains grain products in Zhejiang province, China, risk due multiple consumptions among population. Food samples numbering 713 were collected, LC-MS/MS method used determine toxins. The levels toxins relatively low: toxin at highest levels. food frequency questionnaire collect consumption data. result exposure assessments...