A5008803662- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Neuroscience and Neuropharmacology Research
- SARS-CoV-2 detection and testing
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Educational Games and Gamification
- Congenital Ear and Nasal Anomalies
- Recycled Aggregate Concrete Performance
- Education during COVID-19 pandemic
- COVID-19 diagnosis using AI
- Epilepsy research and treatment
- Facilities and Workplace Management
- Dental Research and COVID-19
- Acupuncture Treatment Research Studies
- Gut microbiota and health
- Pharmacological Effects and Toxicity Studies
- Healthcare during COVID-19 Pandemic
- Leptospirosis research and findings
- Milk Quality and Mastitis in Dairy Cows
- Immune responses and vaccinations
- Skin Protection and Aging
- Medicinal Plants and Neuroprotection
- Cholinesterase and Neurodegenerative Diseases
- Complementary and Alternative Medicine Studies
Fundação Oswaldo Cruz
2020-2024
Universidade Federal do Acre
2022-2023
Universidade Federal do Cariri
2022-2023
Universidade Federal Fluminense
2023
Instituto Federal Fluminense
2023
Universidade Paranaense
2020-2023
Universidade Federal do Rio de Janeiro
2023
Hospital de Clínicas de Porto Alegre
2022
Universidade Federal do Rio Grande do Sul
2016-2018
Although advanced age, male sex, and some comorbidities impact the clinical course of COVID-19, these factors only partially explain inter-individual variability in disease severity. Some studies have shown that genetic polymorphisms contribute to COVID-19 severity; however, results are inconclusive. Thus, we investigated association between ACE1, ACE2, DPP9, IFIH1, IFNAR2, IFNL4, TLR3, TMPRSS2, TYK2 COVID-19. A total 694 patients with were categorized as: (1) ward inpatients (moderate...
Abstract Food production in Amazonian traditional societies often occurs through shifting cultivation that uses few pesticides and relies on ecosystem services provided by natural enemies. However, these sustainable agricultural practices are being threatened increasing livestock mechanised agriculture. This study aimed to evaluate the effects of conversion from Amazon Forest anthropogenic land (shifting pasture) α‐ β‐diversity, functional groups, ant‐mediated predation. Three types habitats...
A assistência técnica do setor da construção civil vem enfrentando o surgimento cada vez mais comum de diversas patologias associadas aos processos construtivos adotados pelas empresas ramo, falta manutenção preventiva e uso inadequado pela parte proprietário, sendo uma das recorrentes a desplacamento peças cerâmicas ao longo utilização edificações, causando série transtornos tanto moradores quanto à construtora que possui obrigação solucioná-las. Esta pesquisa tem como objetivo,...
Reverse transcription loop-mediated isothermal amplification (RT-LAMP) is a rapid method that can replace RT-qPCR. A simple molecular assay for SARS-CoV-2 RNA detection in gold-standard diagnosis through swabs and alternative specimens such as saliva could be helpful promoting genomic surveillance. multicenter study was conducted to evaluate the RT-LAMP an of lineages swab samples. total 350 from individuals with (n = 276) or without 74) COVID-19 tested by RT-qPCR were collected. Paired also...
This report details the design of an online trilingual (English, French, and Portuguese) interactive virtual board game its implementation at Federal University Ceará in Brazil. It was used as a fun alternative to assist chemistry pharmacy undergraduate students reviewing introductory concepts organic reactions: enthalpy, entropy, Gibbs free energy, chemical equilibrium, kinetics, nucleophiles, electrophiles, reactive intermediates. Also, learners positively evaluated method conventional...
Background and Objective: Gamma-decanolactone (GD) is a monoterpene effective against seizures induced by pentylenetetrazole. The mechanism of action GD likely to be via glutamate antagonism. also inhibits intracellular reactive oxygen species (ROS) generation the lipopolysaccharide-induced expression inducible nitric oxide synthase (iNOS) tumor necrosis factor-alpha (TNF-α) in vitro. Considering neuropharmacological profile studied so far, we investigated effect intraperitoneal...
A virtual Game-Based Tournament of Chemistry was developed as an alternative to the traditional problem-solving classes aid students in reviewing and understanding organic acidity basicity concepts. The tournament based on a multilingual board game (English, Portuguese, French, Italian) which aimed facilitate students' interaction collaborative learning enjoyable activity. findings showed that who participated had better outcomes exams compared those partook classes.
Background: Gamma-Decanolactone (GD) is a monoterpene compound that presents anticonvulsant effect in acute and chronic models of epilepsy it acts as noncompetitive glutamate antagonist. Objective: This study evaluated the profile possible mechanism action GD seizures induced by isoniazid (INH; 250 mg/kg), picrotoxin (PCT; 5 mg/kg) 4- aminopyridine (4-AP; 13 male mice. Method: Thirty minutes before convulsants administration, animals received single administration saline, (100 or 300...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can generate a systemic inflammatory response, characterized by cytokine storm and associated with an exaggerated release of proinflammatory cytokines, including tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), IL-17, all which affect the liver. Here, we aimed to evaluate profiles patients suffering from disease (COVID)-19 and/or hepatitis. We subjected 87 serology polymerase chain reaction analysis for hepatitis C...
Abstract Nonhospitalized COVID‐19 and hepatitis C‐coinfected patient presented prolonged RNA shedding mild course of infection. This finding demonstrated the importance long follow‐up these patients.
Leptospirosis is an important infectious disease, which can generate large economic losses, especially in the dairy herd. The pathogen that causes this disease may have its entry Brazilian herds facilitated by existence of a extension land borders. Therefore, objective work was to investigate presence DNA and antibodies against Leptospira spp. samples vaginal mucus serum from naturally infected bovine females small rural farms border region. Blood were collected 70 Holstein cows, between...
Pig farming is an area of livestock that has been developing the most in Brazil and world, with production increasing every year, generating jobs, being great importance for Brazilian economy. In swine production, health enables these animals to reach their highest point development antimicrobials are used, either prophylactically or through food, as growth promoters. Within culture, there a concern regarding antibiotic-resistant bacteria; however, Staphylococcus spp. do not receive...
Patients with kidney disease on Hemodialysis (HD) are susceptible to Coronavirus Disease (COVID-19) due multiple risk factors.
The serological markers for the diagnosis of COVID-19 plays an important role in epidemiological investigation pandemic. This study aims to assess prevalence anti-SARS-CoV-2 hepatitis B and C patients a pre-vaccination period. Between March 2020 January 2021, 199 serum samples from individuals with HBsAg/HBV DNA or anti-HCV/HCV RNA positivity were tested antibodies (IgM IgG) against SARS-CoV-2 using Electrochemiluminescent Immunoassay (ECLIA). Among these, 50.3 % (100/199) positive virus...
Introduction Severe acute hepatitis (SAH) is defined by a severe inflammation of hepatocytes in the liver parenchyma which can lead to an failure, clinical condition with high mortality rate that be triggered several factors but usually associated hepatotropic viruses' infection. In 2022, cases children unknown origin hospitalized Glasgow, Scotland, were reported. Possible causes this include, are not limited to, undiagnosed viral (and non-viral) infections, autoimmune hepatitis, drug and/or...
MicroRNAs (miRNAs) can act as biomarkers and descriptors of the association between infections other diseases, such hepatitis COVID-19. This study aims to investigate role miRNA serum expression according laboratory data concerning Seventy individuals recruited in Southern Southeastern Brazil donated samples were divided into four groups: (i) 20 negative subjects, (ii) presenting hepatitis, (iii) 19 with COVID-19 (iv) 11 Three miRNAs (miR-122, miR-143 miR-223) evaluated using real-time PCR....
Background: Contact between humans and pets, mainly dogs cats, has been increasing in recent years, which may result the spread of infectious agents to new hosts even environment, causing emergencies national international interest. The aim this work was understand phenotypic profile bacteria Enterobacteriaceae family vaginal preputial mucous stray from a border region.Materials, Methods & Results: Swab samples mucosa two regions were collected for later bacterial isolation, biochemical...
O gênero Eucalyptus possui várias espécies passíveis de extração óleos essenciais por suas folhas. objetivo desse trabalho foi realizar uma revisão bibliométrica sobre o tema na base dados scopus e classificar os conforme parâmetros bibliométricos, organizando-os nos programas excel VOSviewer através tabelas gráficos. Foram encontrados 216 documentos últimos 70 anos óleo essencial eucalipto, sendo em sua maioria artigos (199) escritos inglês (72%). país com maior número publicações Brasil,...
Background: Anophthalmia is a rare, congenital condition, defined as the complete absence of eye bulb due to inadequate growth vesicle or optic dome. The malformation can be primary (in complete), secondary presence only residual tissue), degenerative which begins form, but for some reason, it degenerate). This condition rare in dogs, cats, cattle, and sheep. Microscopic evaluation orbital tissue identification always recommended. aim this study was report case bilateral anophthalmia...
Hepatitis B Virus (HBV) has been a cause of acute and chronic hepatitis with progression to cirrhosis hepatocellular carcinoma. Individuals kidney disease (CKD) are especially susceptible HBV infection. Some studies have shown high rates positivity for the infection marker in this population therefore, vaccination becomes safe method prevention. CKD patients generally immunosuppressed lower response vaccine when compared healthy individuals. factors associated non-response older age...