Mohammad Farhadi

ORCID: 0000-0001-6303-1750
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About
Contact & Profiles
Research Areas
  • Hearing, Cochlea, Tinnitus, Genetics
  • Hearing Loss and Rehabilitation
  • Vestibular and auditory disorders
  • Sinusitis and nasal conditions
  • Ear Surgery and Otitis Media
  • Head and Neck Surgical Oncology
  • Head and Neck Cancer Studies
  • Olfactory and Sensory Function Studies
  • Nasal Surgery and Airway Studies
  • Noise Effects and Management
  • Cytomegalovirus and herpesvirus research
  • Connexins and lens biology
  • Pneumonia and Respiratory Infections
  • Biochemical Analysis and Sensing Techniques
  • Obstructive Sleep Apnea Research
  • Cancer, Hypoxia, and Metabolism
  • Laser Applications in Dentistry and Medicine
  • Neuroscience of respiration and sleep
  • Allergic Rhinitis and Sensitization
  • Nerve injury and regeneration
  • Advanced Chemical Sensor Technologies
  • Advanced Neural Network Applications
  • Glioma Diagnosis and Treatment
  • Multisensory perception and integration
  • Angiogenesis and VEGF in Cancer

Iran University of Medical Sciences
2016-2025

Rasool Akram Hospital
2014-2024

Zealand University Hospital
2020-2024

Tehran University of Medical Sciences
2003-2023

Aja University of Medical Sciences
2023

Medical University of Ilam
2017-2023

University of Ulster
2023

Payame Noor University
2022

Næstved Sygehus
2021

Arizona State University
2019-2020

Stem-like tumor cells comprise a highly tumorigenic and therapy-resistant subpopulation, which is believed to substantially influence initiation therapy resistance in glioma. Currently, therapeutic, drug-induced differentiation considered as promising approach eradicate this tumor-driving cell population; retinoic acid well known potent modulator of proliferation normal stem cells. In glioma, knowledge about the efficacy acid-induced target stem-like pool could have therapeutic...

10.1158/1078-0432.ccr-09-1800 article EN Clinical Cancer Research 2010-05-05

Abstract Background Recent surge of olfactory dysfunction in patients who were referred to ENT clinics and concurrent COVID-19epidemic Iran motivated us evaluate anosmic/hyposmic find any relation between these two events. Methods This is a cross-sectional study with an online checklist on voluntary cases all provinces the 12th 17th March, 2020. Cases was defined as self-reported anosmia/hyposmia responders fewer than 4 weeks later (from start COVID-19 epidemic Iran). Variables consist...

10.1101/2020.03.23.20041889 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-03-27

Background:The occurrence of anosmia/hyposmia during novel Coronavirus disease 2019 may indicate a relationship between coincidence olfactory dysfunction and coronavirus .This study aimed to assess the frequency self-reported COVID-19 epidemic in Iran.Methods: This population-based cross sectional was performed through an online questionnaire from March 12 17, 2020.Cases all provinces Iran voluntarily participated this study.Patients completed 33-item patient-reported questionnaire,...

10.47176/mjiri.34.62 article EN cc-by-nc Medical Journal of the Islamic Republic of Iran 2020-10-30

Tumors have been thought to initiate as avascular aggregates of malignant cells that only later induce vascularization. Recently, this classic concept tumor angiogenesis has challenged by the suggestion grow co-opting preexisting host vessels and thus well-vascularized tumors without triggering angiogenesis. To discriminate between these two mechanisms, we used intravital epifluorescence microscopy multi-photon laser scanning confocal visualize C6 microglioma vascularization cell behavior....

10.1172/jci14105 article EN Journal of Clinical Investigation 2002-03-15

The aim of this study was to investigate the effects enzymatic hydrolysis with digestive enzymes camel whole casein and beta-casein (β-CN) on their antioxidant Angiotensin Converting Enzyme (ACE)-inhibitory properties. Peptides in each hydrolysate were fractionated ultra-filtration membranes. activity determined using a Trolox equivalent capacity (TEAC) scale. After hydrolysis, both ACE-inhibitory activities β-CN enhanced. Camel showed significant after pepsin alone pepsinolysis followed by...

10.1017/s0022029911000628 article EN Journal of Dairy Research 2011-09-13

Countries with culturally accepted consanguinity provide a unique resource for the study of rare recessively inherited genetic diseases. Although hereditary hearing loss (HHL) is not uncommon, it genetically heterogeneous, over 85 genes causally implicated in non-syndromic (NSHL). This heterogeneity makes many gene-specific types NSHL exceedingly rare. We sought to define spectrum autosomal recessive HHL Iran by investigating both common and rarely diagnosed deafness-causing genes.Using...

10.1136/jmedgenet-2015-103389 article EN Journal of Medical Genetics 2015-10-07

Regeneration and functional recovery after peripheral nerve damage still remain a significant clinical problem. In this study, alginate/chitosan (alg/chit) hydrogel was used for the transplantation of olfactory ectomesenchymal stem cells (OE-MSCs) to promote regeneration. The OE-MSCs were isolated from mucosa biopsies evaluated by different cell surface markers differentiation capacity. After creating sciatic injury in rat model, transplanted injured area with alg/chit which prepared...

10.1002/jcp.28183 article EN Journal of Cellular Physiology 2019-01-31

Tumors have been thought to initiate as avascular aggregates of malignant cells that only later induce vascularization. Recently, this classic concept tumor angiogenesis has challenged by the suggestion grow co-opting preexisting host vessels and thus well-vascularized tumors without triggering angiogenesis. To discriminate between these two mechanisms, we used intravital epifluorescence microscopy multi-photon laser scanning confocal visualize C6 microglioma vascularization cell behavior....

10.1172/jci0214105 article EN Journal of Clinical Investigation 2002-03-15

Background/objective Studies about the prevalence of coeliac disease in countries western Asia are scarce and there is no study on Iran. The aim this was to determine healthy, Iranian, blood donors. Study design methods Blood samples were obtained from 2000 apparently healthy donors (1580 males, 420 females; mean age 35.5 years, range 18-65 years) at Tehran Donation Centre during a 4 month period November 1998 through February 1999. Total serum IgA measured all donors, deficient cases...

10.1097/01.meg.0000059118.41030.96 article EN European Journal of Gastroenterology & Hepatology 2003-05-01

New cochlear implant (CI) designs and developments in implantation techniques have revolutionized the management of hearing loss. However, still has some disadvantages, such as its potential to initiate an inflammatory response that may lead further hair cell damage. Recent topics investigation been effect glucocorticoids on tissue reduction, glucocorticoid dosage levels, drug-delivery methods. In present study, dexamethasone delivery via a drug-eluting CI was evaluated histologically...

10.1179/1754762811y.0000000024 article EN Cochlear Implants International 2012-03-08

AIM:To investigate the relation of human papillomavirus (HPV) and esophageal squamous cell carcinoma (ESCC) in Iranian patients as compared to normal controls. METHODS:Using MY09/MY11 consensus primers, we prevalence a HPV L1 gene tumor tissues from 38 ESCC cases biopsied endoscopically individuals.We also presence HPV16 HPV18 same samples using type-specific E6/E7 primers.RESULTS: Fourteen (36.8%) but only 5 (13.2%) control were positive for (P = 0.02).Five none 0.05).Three (7.9%) 0.71)....

10.3748/wjg.v11.i8.1200 article EN cc-by-nc World Journal of Gastroenterology 2005-01-01
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