Miroslav Hájek

ORCID: 0000-0001-6558-835X
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Research Areas
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Forest Management and Policy
  • Conservation, Biodiversity, and Resource Management
  • Bioeconomy and Sustainability Development
  • Crystallography and molecular interactions
  • Land Use and Ecosystem Services
  • DNA and Nucleic Acid Chemistry
  • Advanced biosensing and bioanalysis techniques
  • Telomeres, Telomerase, and Senescence
  • Urban Green Space and Health
  • Sustainable Supply Chain Management
  • RNA Interference and Gene Delivery
  • Environmental Conservation and Management
  • Economic and Business Development Strategies
  • African Botany and Ecology Studies
  • Vehicle emissions and performance
  • Ecology and Vegetation Dynamics Studies
  • Glycosylation and Glycoproteins Research
  • Land Rights and Reforms
  • Synthesis and Properties of Aromatic Compounds
  • Environmental Sustainability in Business
  • Medicinal Plants and Bioactive Compounds
  • Fire effects on ecosystems
  • Microbial Natural Products and Biosynthesis

Czech University of Life Sciences Prague
2014-2024

Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry
2014-2023

University of Namibia
2023

Czech Academy of Sciences
2005-2014

Core-shell nanoparticles based on fluorescent nanodiamonds coated with a biocompatible N-(2-hydroxypropyl)methacrylamide copolymer shell were developed for background-free near-infrared imaging of cancer cells. The particles showed excellent colloidal stability in buffers and culture media. After conjugation cyclic RGD peptide they selectively targeted integrin αvβ3 receptors glioblastoma cells high internalization efficacy.

10.1039/c4nr02776k article EN cc-by-nc Nanoscale 2014-07-25

Apoptosis is one of the presumptive causes CD4+ T cell depletion during HIV infection and progression to AIDS. However, precise role HIV-1 in this process remains unexplained. protease (PR) has been suggested as a possible factor, but direct link between PR enzymatic activity apoptosis not established. Here, we show that expression active induces death HeLa HEK-293 cells via mitochondrial apoptotic pathway. This conclusion based on vivo observations localization mitochondria, key player...

10.1186/1742-4690-11-37 article EN cc-by Retrovirology 2014-05-20

Innovations are a key component of the forest bioeconomy. Many types innovations needed for an efficient bioeconomy to be deployed. This article aimed analyze scientific literature on topic in bioeconomy, understand where we and likely future, considering technologies, business models, etc. First, literature, form peer-reviewed articles indexed Web Science, was compiled comprehensive dataset, which analyzed most important authors, their affiliations, regions they come from, journals papers...

10.3390/f12101392 article EN Forests 2021-10-12

A unified approach to meroterpenoids applanatumols B, V, W, X, and Y produced by the medicinal fungus Ganoderma applanatum 2′-epi-spiroapplanatumine O is presented. The key synthetic sequence consists of a tandem anionic ketone allylation/oxy-Cope rearrangement/α-oxygenation furnishing an α-aminoxy persistent radical effect-based 5-exo-trig cyclization leading trisubstituted cyclopentane core. relative configuration applanatumol V has be revised. Some compounds display significant cytotoxic...

10.1021/acs.orglett.2c01633 article EN Organic Letters 2022-06-19

The main objective of this article is to examine how individual policy instruments contribute reducing transport carbon emissions from in groups EU countries. Multiple panel regression analysis was chosen as the research method, impact tax revenues on GHG being expected be negative. results suggest that influence particular varies between countries, differences partly due national legislations. Focusing explanatory variable price aviation allowances, supports our hypothesis. findings...

10.1016/j.trd.2021.103054 article EN cc-by-nc-nd Transportation Research Part D Transport and Environment 2021-09-29

Sago ( Metroxylon spp.), a traditional staple food that naturally grows in Papuan forests, plays vital role the security of local inhabitants and is equally important non-food industries. Changes forest cover to other land uses might lead shifts sago ecosystem, which could also affect production nutrients. Currently, there lack studies correlating vegetation changes nutrient profiles. This research article aims explore area their potential relationship ecosystem profiles sago. NDVI...

10.3389/ffgc.2025.1373768 article EN cc-by Frontiers in Forests and Global Change 2025-02-13

The Czech forests occupy 33.7% of the total country area; thus, wood and non-wood forest products (NWFPs) are important resources for country. To date, has not adopted a bioeconomy strategy. A is defined as all activities that relate to ecosystem services (FES). This study aimed provide an initial evaluation regarding use related factors, make recommendations on developing consumption promoting other FES adoption strategy in research was part nationwide survey June 2019. An online panel 1050...

10.3390/su12020566 article EN Sustainability 2020-01-11

Wood charcoal (WCH) is a sustainable biofuel for rural and urban users because of its higher energy density emission marginal smoke when compared with firewood. Besides helping the poor majority who cannot afford kerosene, electricity or liquid petroleum gas (LPG), WCH key source income livelihood. This work aimed at quantifying volume production as well appraising socio-economics, including environmental impacts, especially impact long-term deforestation forest degradation in Africa....

10.3390/f12050568 article EN Forests 2021-05-01

The general objective of the study was to assess main drivers for visiting forest and frequency visits in Czech Republic. A nationwide collection data sociological research as part Market & Media Lifestyle Research Project carried out every year Republic under licensed cooperation with Kantar Media. project is unique by large scope questions questionnaires high number respondents. total 8794 inhabitants aged 12 years above from all regions were involved survey 2018. Information about...

10.3390/f11040414 article EN Forests 2020-04-07

Background and Objectives: Forest-based bioeconomies have been adopted as the national forest strategies in many European countries. However, Czech Republic, bioeconomy has not officially included policies. The main objective of paper was to review current policy Republic meeting purposes forest-based bioeconomy. To better understand opportunities shortcomings strategy implementation a country, comparison study Germany also carried out. Methods: A done based on following research questions:...

10.3390/f11060608 article EN Forests 2020-05-27

Ecosystem services are investigated from many perspectives, but there very few studies comparing the perception of forest and demand for ecosystem (FES) in a cross-cultural analysis. This study aims to map FES find out visitors both Czech Chinese societies. Data were collected by structured questionnaire among three different groups respondents (n = 847) six areas. The questions focused on FES, expectations forest, preference visual form willingness visitors. Analysis demonstrates that some...

10.1007/s10342-022-01478-0 article EN cc-by European Journal of Forest Research 2022-07-23

This study was aimed at assessing the indicators of a sustainable forest bioeconomy in Ghana for three decades (1990–2020). Sustainable development is system geared towards improving people’s socioeconomic and environmental situation through forestry, yet Ghana, it neither heard about nor well understood by many people. A good knowledge bioeconomic will enhance people to become custodians ecosystems instead being destroyers. Field secondary data were collected analyzed using IBM SPSS 29.0,...

10.3390/f14040804 article EN Forests 2023-04-14

Fertilizer subsidies may constitute a key economic tool with which to provide food for the growing population. Therefore, this work aimed (i) assess effectiveness of subsidized chemical (NPK) fertilizer use in production by comparing crop output between developed and developing regions (ii) examine benefits organic need its such as Africa. Secondary data from 2000 2019 on global use, production, income, other agro-environmental parameters, climate soil, were collected international databases...

10.3390/su13169408 article EN Sustainability 2021-08-22

Sustainable forest bioeconomy (SFB), as a multidimensional approach for establishing mutual benefits between ecosystems, the environment, economy, and humans, is nature-based solution promising future. The study aims to evaluate potential of carbon stocks (Cstocks) variability SFB. It hypothesized that decrease in Cstocks related an increase population agriculture, which caused area growing stock consequently affected Primary secondary data were collected from field, national, international...

10.3390/f15020256 article EN Forests 2024-01-29

The concept of sustainable development is currently known and used in many contexts across a wide range industries. Nevertheless, specific approaches to achieving the strategy sustainability can be found individual sectors. beginnings management forestry go back mid-18th century. Currently, certification systems contribute behaviour forests. In Czech Republic, this concerns particular PEFC FSC systems. Both these include two different processes, forest chain custody certification, i.e....

10.17221/16/2015-jfs article EN cc-by-nc Journal of Forest Science 2015-08-24

The project for community forest of Namibia has a mandate to ensure that rural communities manage and utilize resources sustainably in order promote socio-economic development. Despite the absence true forests from Namibia, which makes it difficult timber industry grow, there is still an abundance non-timber products Namibian forests. This research aimed at assessing monetary value Uukolonkadhi Community Forest. covered period five production years. nine selected was given terms. results...

10.11118/actaun201967010197 article EN cc-by-nc-nd Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis 2019-02-28

Millions of local communities in southern Africa depend on forest ecosystems and the goods services they provide for their livelihoods. This paper aims to assess socio-economic benefits a changing climate by focusing products Colophospermum mopane (C. mopane) Kunene Omusati regions northern Namibia. We used C. product data from 2011 2021. Our analyses showed that harvested five main mopane, namely firewood, poles, droppers, rafters, roots. Firewood poles were primary communities, mainly...

10.3390/f14020290 article EN Forests 2023-02-02

Abstract In recent years, there has been growing interest in public valuation for forest ecosystem services policymaking. This paper investigates the public’s perception of Czech services, i.e., provisioning, regulating and cultural with associated factors (changes cover, production, respondents’ characteristics). The performance was gathered from a nationwide survey 2020. Coordination Information on Environment Land Cover information 2000 2018 used observation cover changes. Coniferous...

10.1186/s12302-023-00802-8 article EN cc-by Environmental Sciences Europe 2023-11-01

Abstract Forests and human connection with nature have a major impact on health. Through exercise recreation in the forest, people receive many benefits from forest ecosystem services (FES) which positive their physical mental The paper tackles two main goals i) first one is an overview of existing literature related to health well-being derived forests countries Central Europe published Scopus database. ii) second goal was create policy instruments cultural (FCS) documents selected European...

10.2478/forj-2021-0013 article EN cc-by-nc-nd Central European Forestry Journal 2021-11-14

Galectins, a class of carbohydrate-binding proteins, play crucial role in various physiological and disease processes. Therefore, the identification ligands that efficiently bind these proteins could potentially lead to development new therapeutic compounds. In this study, we present method involves screening synthetic click glycopeptide libraries identify lectin-binding with low micromolar affinity. Our methodology, initially optimized using Concanavalin A, was subsequently applied binders...

10.1002/cplu.202300567 article EN cc-by ChemPlusChem 2023-11-09

The 2012 European Bioeconomy Strategy has been adopted in some countries' national policies. However, it not officially included the Czech Republic's policy. In Sweden, policy and National Forest Programme (NFP). paper reviews current forest Republic meeting purposes of forestbased bioeconomy by performing a comparative study between Sweden. As principles are core values Swedish NFP aims only to deliver sustainable products ecosystem services support enterprises but also achieve...

10.1505/146554821834777260 article EN The International Forestry Review 2021-12-01
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