- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Autoimmune Neurological Disorders and Treatments
- Peripheral Neuropathies and Disorders
- Multiple Sclerosis Research Studies
- Advanced Biosensing Techniques and Applications
- Cancer Immunotherapy and Biomarkers
- CAR-T cell therapy research
- Contact Dermatitis and Allergies
- Chronic Lymphocytic Leukemia Research
- Tuberculosis Research and Epidemiology
- Bacterial Infections and Vaccines
- Autoimmune and Inflammatory Disorders Research
- Food Allergy and Anaphylaxis Research
- interferon and immune responses
- Systemic Lupus Erythematosus Research
- Tryptophan and brain disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Sphingolipid Metabolism and Signaling
- Cerebral Venous Sinus Thrombosis
- Cerebrovascular and Carotid Artery Diseases
- Toxin Mechanisms and Immunotoxins
- Drug-Induced Adverse Reactions
- Evolutionary Psychology and Human Behavior
- Rheumatoid Arthritis Research and Therapies
Hospital de Santo António
2024
Centro Hospitalar do Porto
2022-2023
Hospital Vila Franca de Xira
2019
Centro de Medicina de Reabilitacao do Alcoitão
2019
Hospital Garcia de Orta
2019
University of Lisbon
2014-2016
Since 2010 the 13-valent pneumococcal conjugate vaccine (PCV13) replaced 7-valent (PCV7) as leading used in children through private sector. Although neither of PCVs were significantly adults, changes adult invasive disease (IPD) expected due to herd protection. We characterized n=1163 isolates recovered from IPD adults 2012-2014 with goal documenting possible serotype prevalence and antimicrobial resistance. Among 54 different serotypes detected, most frequent, accounting for half all IPD,...
Among the 1660 isolates recovered from invasive pneumococcal disease (IPD) in adults (> = 18 yrs) 2008–2011, a random sample of ≥50% each serotype (n 871) was chosen for MLST analysis and evaluation presence type pilus islands (PIs). The genetic diversity high with 206 different sequence types (STs) detected, but it varied significantly between serotypes. STs represented 80 clonal complexes (CCs) according to goeBURST six more frequent accounting than half (50.6%) isolates—CC156 (serotypes...
There is limited information on the serotypes causing non-invasive pneumococcal pneumonia (NIPP). Our aim was to characterize pneumococci NIPP in adults determine recent changes serotype prevalence, potential coverage of vaccines and antimicrobial resistance. Serotypes susceptibility profiles a sample 1300 isolates recovered from adult patients (≥18 yrs) between 1999 2011 (13 years) were determined. Serotype 3 most frequent cause accounting for 18% isolates. The other common 11A (7%), 19F...
<h3>Background</h3> Rheumatoid Arthritis (RA) is known to be associated with an increased risk of serious infection. The elevated susceptibility patients RA can explained by the pathobiology disease itself, impact chronic comorbid conditions, as well side effects immunosuppressive treatment<sup>1</sup>. <h3>Objectives</h3> aim this study was understand and its therapies in development infection a cohort our outpatient clinic. <h3>Methods</h3> Out almost 450 cohort, retrospective analysis...
Hydrocephalus is a known complication of central nervous system (CNS) vasculitis secondary to infectious diseases. We present an unusual case primary CNS (PCNSV) complicated by communicating hydrocephalus. A patient in their 50s with few months’ history headache, psychomotor slowing and frequent falls presented acute left temporo-parieto-occipital infarction. Angiography revealed multiple arterial irregularities the anterior circulation bilaterally, CSF was inflammatory remaining study...
Introdução: Em crianças com diagnóstico de Perturbação da Comunicação é essencial capacitar os parceiros comunicativos como agentes intervenção, dando continuidade ao uso estratégias terapêuticas contingentes, nas rotinas diárias, melhorando o desenvolvimento comunicativo e a interação; Objetivo: Apresenta-se uma proposta programa funcional, centrado nos cuidadores, para em idade pré-escolar pretendendo-se: i) Capacitar cuidadores no que se refere à identificação necessidades...