A5031752863- Antibiotics Pharmacokinetics and Efficacy
- Orthopedic Infections and Treatments
- Intensive Care Unit Cognitive Disorders
- Orthopaedic implants and arthroplasty
- Pneumonia and Respiratory Infections
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Poisoning and overdose treatments
- Antibiotic Use and Resistance
- Cardiac Arrest and Resuscitation
- Infectious Diseases and Tuberculosis
- Long-Term Effects of COVID-19
- Erythropoietin and Anemia Treatment
- Nosocomial Infections in ICU
- Total Knee Arthroplasty Outcomes
- Blood transfusion and management
Astana Medical University
2022-2025
Meropenem is a widely prescribed β-lactam antibiotic. exhibits maximum pharmacodynamic efficacy when given by continuous infusion to deliver constant drug levels above the minimal inhibitory concentration. Compared with intermittent administration, administration of meropenem may improve clinical outcomes.To determine whether reduces composite mortality and emergence pandrug-resistant or extensively drug-resistant bacteria compared in critically ill patients sepsis.A double-blind, randomized...
This case report highlights the use of continuous infusion meropenem in a 42-year-old septic female patient with periprosthetic infection and end-stage renal disease receiving prolonged intermittent replacement therapy (PIRRT). Antibiotic patients has its own peculiarities. There are many studies on optimal dosing regimen for dysfunction, but duration these limited. The was admitted complaints wounds, necrosis zones right upper limb, restriction joint movements, temperature increase up to 38...
The present report highlights a case of successful treatment 59-year-old patient who experienced pain, swelling, hyperemia, the presence wound right knee joint, impaired function lower limb, weakness, fatigue, and labored breathing. Sepsis was detected in as result periprosthetic infection with concomitant severe COVID-19. admitted to hospital for 59 days, 57 days at intensive care unit. A therapy multiple organ failure involved complex using antiviral combined antibiotic therapy, taking...
This article highlights a clinical case of successful treatment 79-year-old multimorbid patient with hip fracture resulting from household injury. On the first day, patient's injury was complicated by infection and pneumonia. As result, arterial hypotension, tachysystole, respiratory failure progressed. With manifestations sepsis, transferred to intensive care unit. Surgical in such situation contraindicated due high operational anesthesiological risks, unstable severe condition patient, as...
Background and Objectives: The prolonged infusion of meropenem is recommended by guidelines for the treatment sepsis. However, studies provide controversial data on advantages infusions over intermittent ones. In our opinion, this can be related to age, which possibly distorts final data, as older people have age-related characteristics. study, we analyzed ventilatory status, laboratory tests vital signs patient carried out microbiological cultures. Materials Methods: This was a prospective...
Background Prolonged infusion of meropenem is recommended by guidelines for the treatment sepsis. However, use prolonged infusions not registered FDA and considered an off-label application. Also, some studies provide controversial data on advantage over intermittent ones. It known that age independent predictor mortality in patients with sepsis septic shock. In this study, we evaluated effectiveness continuous geriatric trauma sepsis.This was a single-center case series 7 who received from...
Introduction. The increasing proportion of the aging population and overweight people with various joint problems leads to an increased demand for replacements. As number arthroplasty surgeries continues rise, persistent incidence periprosthetic infections highlights need a comprehensive evolving approach. In addition preoperative period, it is also necessary consider course intraoperative, greater extent postoperative when development infection occurs. This case indicative fact that...
This article highlights a case of high-dose ferric carboxymaltose (Ferinject
Despite advances and improvements in infection prevention techniques, periprosthetic joint is a serious complication after total replacement. Prevention of purulent-septic complications the most important strategy to combat this disabling complication, should begin with identifying patient-related risk factors The aim: identification associated development arthroplasty large joints. Methods. A retrospective review medical records 71 patients who underwent orthopedic surgery from September...