A5064580696- Bacterial Identification and Susceptibility Testing
- Antibiotic Resistance in Bacteria
- Healthcare Regulation
- Antibiotics Pharmacokinetics and Efficacy
- Bacterial biofilms and quorum sensing
- Infections and bacterial resistance
- Healthcare during COVID-19 Pandemic
- Public Health in Brazil
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Use and Resistance
- Clostridium difficile and Clostridium perfringens research
- Escherichia coli research studies
- Probiotics and Fermented Foods
- Oral microbiology and periodontitis research
- Pharmaceutical and Antibiotic Environmental Impacts
- Microbial Metabolism and Applications
- Education during COVID-19 pandemic
- Blood disorders and treatments
- Yersinia bacterium, plague, ectoparasites research
- Antimicrobial Peptides and Activities
- Nosocomial Infections in ICU
- COVID-19 Impact on Reproduction
- Fungal Infections and Studies
- Oral and gingival health research
- Oral health in cancer treatment
Universidade Federal do Espírito Santo
2011-2024
Universidade Vale do Rio Doce
2011
Universidade Federal de Minas Gerais
2006-2010
Because of the inherent immunosuppression cancer patients opportunistic infections by Candida spp, occur frequently. This study aimed to identify species in oral mucosa 59 with orogastric (OGC) and analyze immunological phenotype these patients. The yeasts were identified MALDI-TOF mass spectrometry (MS). For all isolates, we performed phospholipases proteinases assays, vitro adherence buccal epithelial cells (BEC), minimum inhibitory concentration antifungal drugs determined cytokine...
Aims: The purpose of this study was to purify and characterize a bacteriocin produced by Eikenella corrodens A32E2. Methods Results: Peptostreptococcus anaerobius ATCC27337 used as indicator strain in antagonistic assays for bacteriocin-producing E. Protein extraction influenced pH buffer composition. protein active the range 6–8. Inhibitory activity lost both heating treatment with proteolytic enzymes decreased organic solvents. substance is rather unstable but maintains 100% its after...
Antagonistic abilities may confer ecological advantages for micro-organisms in competitive ecosystems. However, reports regarding this phenomenon Eikenella corrodens are not available.Nineteen E. strains, isolated from the oral cavity of human beings without periodontal disease (n = 5) and with aggressive 9) chronic periodontitis, as well a reference strain (E. ATCC23834), were evaluated antagonistic activity. The following indicators used: Porphyromonas gingivalis FDC381, Prevotella...
Ertapenem and piperacillin/tazobactam are beta-lactam antibiotics with a broad spectrum of activity used for the treatment mixed infections in which Bacteroides fragilis Escherichia coli play an important aetiological role. In this study, activities ertapenem (MIC time-kill kinetics) against these bacteria were compared. MICs determined by agar dilution method, time slope curves analysed. vitro pharmacodynamic assays, pure cultures E. B. exposed to peak concentrations (8.0 microg ml(-1))...
Aim: To evaluate the activity of five antimicrobials against young and mature Stenotrophomonas maltophilia biofilms. Materials & methods: Nineteen clinical strains from hemoculture hemodialysis patients were tested for biofilm kinetics, MIC minimum inhibitory concentration (MBIC) in Results: All moderate producers. showed total susceptibility to levofloxacin trimethoprim-sulfamethoxazole partial resistance ceftazidime (63.2%) gentamicin (21%). Young biofilms lowest MBIC/MIC ratio gentamicin,...
The empiric antimicrobial therapy for bacteremia of long-term hemodialysis (HD) outpatients is currently based on the combination vancomycin and gentamicin because high frequency isolated Staphylococcus species. trough level range from 15 to 20 mcg/mL expected therapeutic success against methicillin-resistant aureus with minimum inhibitory concentration (MIC) ≥1.0 mcg/mL. Despite availability clinical practice guidelines drug monitoring, these target serum concentrations are not reached in...
PremiTest, a microbial inhibition test for the screening of antimicrobial residues, was validated according to criteria established by Decision 2002/657/EC. Sensitivity, detection capability (CCβ), specificity, selectivity, robustness and applicability were evaluated. The methodology involves technique solvent extraction, which increases wider range antibiotics. following CCβ values in poultry muscle found: penicillin G ≤ 12.5 µg kg(-1), total sulfonamides 75 erythromycin kg(-1) lincomycin...
The aim of this study was to identify phenotypic changes in a laboratory-derived strain ertapenem-resistant Escherichia coli (Ec-ERT) when compared its susceptible parent (Ec-WT). In both strains, we assessed the effects ertapenem via time-kill curves and occurrence cross resistance with other beta-lactams. strains were based on growth pattern, biochemical-physiological profile subproteome using 2D-DIGE followed by MALDI-TOF/TOF MS. To assess virulence, employed murine model intraperitoneal...
(2010). In Vitro Selection of Ertapenem and Piperacillin/Tazobactam-Resistant Strains Bacteroides fragilis Analysis their Virulence in Gnotobiotic Mice. Journal Chemotherapy: Vol. 22, No. 4, pp. 259-263.
Aim: To evaluate the impact of first year COVID-19 pandemic on antibiotic dispensation in three Brazilian hospitals. Methods: Stock movement was accessed from pharmacy databases and microbiological reports 2018 to 2021. Results: Reduced occurred during 2020 all The most significant reduction April at Hospital Doutor Jayme dos Santos Neves (∼58%), May Roberto Arnizaut Silvares (∼66%) Dório Silva (∼29%). However, azithromycin increased hospitals 2020. Macrolide-resistant bacterial isolates...
Em estudos anteriores, a Concentração Inibitória Mínima (CIM) de Vancomicina foi associada ao pior prognóstico pacientes com bacteremia causada por Staphylococcus aureus. Visto isso, vigilância do perfil microbiológico dos hospitais faz-se necessária, sobretudo no contexto da pandemia COVID-19, devido alto número internados períodos prolongados sujeitos infecções secundárias. Nosso objetivo, então, descrever distribuição CIM vancomicina antes e durante em um hospital público Espírito Santo....