Xiangpeng Zhan

ORCID: 0000-0001-6872-3705
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About
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Research Areas
  • Bladder and Urothelial Cancer Treatments
  • Urinary and Genital Oncology Studies
  • Renal cell carcinoma treatment
  • Urological Disorders and Treatments
  • Multiple and Secondary Primary Cancers
  • Prostate Cancer Diagnosis and Treatment
  • Renal and related cancers
  • Esophageal Cancer Research and Treatment
  • Prostate Cancer Treatment and Research
  • Peptidase Inhibition and Analysis
  • Genital Health and Disease
  • Ferroptosis and cancer prognosis
  • Hormonal and reproductive studies
  • Economic and Financial Impacts of Cancer
  • Cancer Immunotherapy and Biomarkers
  • Cancer survivorship and care
  • Pelvic floor disorders treatments
  • Urologic and reproductive health conditions
  • Suicide and Self-Harm Studies
  • Genetic Associations and Epidemiology
  • Ovarian function and disorders
  • Circular RNAs in diseases
  • COVID-19 and healthcare impacts
  • Nuclear Receptors and Signaling
  • Pharmacological Effects and Assays

Nanchang University
1970-2025

First Affiliated Hospital of Jiangxi Medical College
2024-2025

First Affiliated Hospital of Nanchang University
1970-2024

Jiangxi Pingxiang People's Hospital
2023

Putian University
2023

Education Department of Fujian Province
2022

Second Military Medical University
2022

Beijing University of Chemical Technology
2009

The Visceral Adiposity Index (VAI) is a straightforward and gender-specific marker that combines anthropometric measurements with lipid profiles. objective of this study was to evaluate the relationship between VAI coronary heart disease (CHD).

10.3389/fendo.2023.1296398 article EN cc-by Frontiers in Endocrinology 2024-01-08

Abstract Background Renal cell carcinoma (RCC) survival has improved due to recent developments in RCC treatment. Therefore, other co-morbid conditions may have a more critical role. This study aims explore the common causes of death patients with improve management and RCC. Method We used Surveillance, Epidemiology, End Results (SEER) (1992–2018) database get calculated percentage total deaths six kinds cause (COD) cumulative incidence for each selected over time. The joinpoint regression...

10.1186/s12889-023-15647-2 article EN cc-by BMC Public Health 2023-04-26

Abstract Background This study aimed to investigate the relationship between serum testosterone levels and risk of congestive heart failure (CHF) in adult males. Previous research has suggested a potential link cardiovascular health, but findings have been inconclusive. Methods was cross-sectional, data were obtained from 2011–2016 cycle National Health Nutrition Examination Survey (NHANES), which included sample 6,841 male participants. Serum measured using standardized assay, CHF status...

10.1186/s12958-023-01171-w article EN cc-by Reproductive Biology and Endocrinology 2024-01-02

The aim of this study is to investigate the trends in incidence and mortality, explore any change survival penile cancer United States.

10.3389/fonc.2022.891623 article EN cc-by Frontiers in Oncology 2022-06-17

Abstract Background Suicide was an important cause of death in prostate cancer. This study intended to investigate trends suicide mortality among cancer (PCa) survivors from 1975 2019 the United States. Method We identified PCa Surveillance, Epidemiology, and End Results (SEER) program January December 2019. Standardized rate (SMR) calculated d assess relative risk compared with general men population. Poisson regression model performed test for trend SMRs. The cumulative clinical burden...

10.1186/s12889-023-17589-1 article EN cc-by BMC Public Health 2024-01-05

To construct a prognostic model to predict the cancer-specific survival (CSS) for bladder cancer patients with lymph node-positive. We enrolled 2,050 diagnosed node-positive from Surveillance Epidemiology and End Results (SEER) database (2004-2015). All were randomly split into development cohort (n = 1,438) validation 612) at ratio of 7:3. The univariate multivariate Cox regression analysis performed identify factors. A nomogram predicting CSS was established based on results analysis. Its...

10.3389/fonc.2022.789028 article EN cc-by Frontiers in Oncology 2022-02-03

This study utilized data from the National Health and Nutrition Examination Survey (NHANES) to investigate association between systemic immune-inflammation index (SII) erectile dysfunction (ED) in adult males. The SII is a novel derived counts of neutrophils, lymphocytes, platelets peripheral blood serves as comprehensive indicator immune response inflammation levels. included 3601 participants NHANES 2001-2004 cycle. Covariates such age, race, marital status, education, smoking, alcohol...

10.1097/md.0000000000035724 article EN cc-by-nc Medicine 2023-11-10

Predicting the accurate preoperative staging of bladder cancer (BLCA), which markedly affects treatment decisions and patient outcomes, using traditional clinical parameters is challenging. Nevertheless, emerging studies in radiomics, especially machine learning-based computed tomography (CT) image-based hold promise improving stage prediction accuracy various tumors. However, comparative performance utility models for BLCA are under investigation.

10.1002/mp.17288 article EN Medical Physics 2024-07-08

Purpose. Partial cystectomy was investigated as a method of bladder preservation with better disease outcomes than transurethral tumor resection in T1 high-grade cancer patients. Method and materials. The national Surveillance, Epidemiology, End Results database (SEER) (2004–2015) were used to obtain patients diagnosed cancer, finally, 25263 enrolled our study. Kaplan–Meier the log-rank test performed analyze outcome overall survival (OS) cancer-specific (CSS) between undergoing partial...

10.1155/2022/3016725 article EN cc-by Journal of Oncology 2022-10-25

Background: Suicide in cancer survivors is a major public health concern, but its trends and risk factors are not well understood. This study aimed to investigate the standardized mortality rate (SMR) suicide among United States. Methods: Using data from SEER-9 database US Mortality data, we identified 3,684,040 diagnosed between 1975 2020. The SMR of was calculated, Poisson regression analysis used evaluate risk. Subgroup analyses were performed based on age, gender, race, tumor site,...

10.18632/aging.205451 article EN cc-by Aging 2024-01-22

Immune cell signatures have been implicated in cancer progression and response to treatment. However, the causal relationship between immune prostate (PCa) is still unclear. This study aimed investigate potential associations PCa using Mendelian randomization (MR).

10.18632/aging.205942 article EN cc-by Aging 2024-06-17

To establish a prognostic model that estimates cancer-specific survival (CSS) probability for muscle-invasive bladder cancer patients undergoing partial cystectomy. Patients and Methods. 866 from the Surveillance, Epidemiology, End Results (SEER) database (2004-2015) were enrolled in our study. These randomly divided into development cohort (n = 608) validation 258) at ratio of 7 : 3. A Cox regression was performed to select predictors associated with CSS. The Kaplan-Meier method used...

10.1155/2022/2665711 article EN cc-by Journal of Oncology 2022-03-01

Abstract Background Penile squamous cell carcinoma (PSCC) survival had no significant improvement since 1990 in the United States. This study aims to get insight into changing trend and distribution of death causes PSCC. The epidemiology PSCC is also investigated. Methods Surveillance, Epidemiology, End Results (SEER) (1992–2018) database utilized patients diagnosed with penile carcinoma. incidence, age, cause, outcome are analyzed for all each race. Three thousand four hundred twenty‐three...

10.1002/cam4.4614 article EN cc-by Cancer Medicine 2022-03-03

The goal of this study is exploring the disparity incidence, mortality and survival outcome among transitional cell carcinomas (TCCs) in 4 parts urinary system. This comprehensively evaluates these disparities using Surveillance, Epidemiology, End Results (SEER) (2000-2018) database. According to SEER database, tract divided into parts: bladder, renal pelvis, ureter, urethra. joinpoint regression was used analyze secular trend incidence incidence-based (IBM). Kaplan-Meier method with...

10.1097/md.0000000000036063 article EN cc-by-nc Medicine 2023-11-17

Abstract Purpose To study prognostic values of bladder neck involvement (BNI) and survival outcomes in non‐muscle‐invasive cancer (NMIBC). Method materials The national Surveillance, Epidemiology, End Results database (2004–2015) was applied to gain further insight into the BNI 19,919 patients diagnosed with NMIBC were included our study. We used Kaplan–Meier method log‐rank test subgroup analyses evaluate cancer‐specific (CSS) overall (OS). In addition, multivariable Cox proportional hazard...

10.1002/cam4.4219 article EN cc-by Cancer Medicine 2021-08-23

Metastatic renal cell carcinoma (mRCC) is usually considered to have a poor prognosis, which has high risk of early death (≤3 months). Our aim was developed predictive nomogram for mRCC.The SEER database accessed obtain the related information 6,005 mRCC patients between 2010 and 2015. They were randomly divided into primary cohort validation in radio 7:3. The optimal cut-off point regarding age at diagnosis tumor size identified by X-tile analysis. Univariate multivariate logistic...

10.3389/fsurg.2022.871577 article EN cc-by Frontiers in Surgery 2022-03-22

The effect of lymph node resection on the prognosis bladder cancer (BLCA) patients receiving radical cystectomy should not be ignored. Our aim was to explore prognostic value log odds negative nodes/T stage (LONT) and construct a more effective nomogram based LONT predict cancer-specific survival (CSS) in postoperative BLCA patients. Patients diagnosed with after between 2004 2015 Surveillance, Epidemiology, End Results (SEER) database were enrolled. We randomly split (7:3) these into...

10.3389/fonc.2022.895413 article EN cc-by Frontiers in Oncology 2022-07-19

To compare the efficacy and safety between conservative treatment surgery for patients with small (1-3cm) nonfunctional adrenal incidentaloma (NFAI). The NFAI who received or in our hospital from November 2018 to December 2019 were retrospectively collected. A total of 83 included this study. They divided into two groups according methods: group (n=51) (n=32).Then patients' demographics, tumor characteristics, functional indicators complications compared. Statistical analysis was performed...

10.3389/fendo.2023.1119251 article EN cc-by Frontiers in Endocrinology 2023-02-01

Previous studies have confirmed the higher risk of bladder cancer (BC) and rectal (RC) development among prostate (PCa) patients receiving radiotherapy. In this study, we intend to explore long-term trend in second BC RC incidence PCa undergoing radiotherapy.We identified first primary diagnosed between 1975 2014 from Surveillance, Epidemiology, End Results (SEER)-9 registries. Standardized ratios (SIRs) were calculated by calendar year diagnosis radiotherapy not. P trends evaluated using...

10.1177/10732748231177544 article EN cc-by-nc Cancer Control 2023-01-01

Objective To investigate the association between radiotherapy and risk of second malignant neoplasm (SMN) development among patients with bladder cancer (BC). Overall survival (OS) is compared developing SMN without. Method We identified diagnosed BC from Surveillance, Epidemiology, End Results (SEER) database. The an defined as any occurring more than 5 years after diagnosis BC. Fine-Gray competing regression used to estimate probability SMN. radiotherapy-associated (RR) for SMNs assessed...

10.3389/fonc.2022.953615 article EN cc-by Frontiers in Oncology 2022-11-16
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