A5066898547- Monoclonal and Polyclonal Antibodies Research
- Advanced biosensing and bioanalysis techniques
- Antiplatelet Therapy and Cardiovascular Diseases
- Neuropeptides and Animal Physiology
- Glycosylation and Glycoproteins Research
- S100 Proteins and Annexins
- Synthesis and Biological Evaluation
- Migraine and Headache Studies
- Atherosclerosis and Cardiovascular Diseases
- Inflammatory mediators and NSAID effects
Weifang Medical University
2023-2024
Digoxin is a cardiac glycosylated steroid-like drug with positive inotropic effect and has been widely used in treating congestive heart failure, atrial fibrillation, flutter, other diseases. also dangerous drug, which can cause poisoning at low blood concentration (2.73-3.9 nmol/L, i.e., 2.14-3.05 ng/mL). Therefore, the timely detection of patient's plays significant role controlling concentration, reducing occurrence events, maximizing therapy. In this study, DNA vector for expression...
Introduction: Calcitonin gene-related peptide (CGRP) is involved in trigeminal neuralgia and migraine, measuring the CGRP concentration serum crucial for early prediction of these conditions. Current methods detection are primarily radioimmunoassay, which needs radioactive substances enzyme-linked immunosorbent assays (ELISAs) need long time some have a narrow range. Methods: The genes anti-CGRP antibody variable regions were cloned into pDong1 vector to obtain pDong1/Fab-CGRP, with...
Introduction: Ticagrelor is extensively utilized for the treatment of acute coronary syndromes (ACS), but its platelet aggregation inhibitory effects can potentially result in tissue bleeding, posing a serious risk to patients' lives. Methods: In this study, we developed highly sensitive full length anti-ticagrelor Quenchbodies (Q-bodies) fast monitoring ticagrelor both solution and serum first time. coupled with N- hydroxysuccinimide (Ticagrelor-NHS) ester was also designed synthesized...