A5046961373- Musculoskeletal pain and rehabilitation
- Spine and Intervertebral Disc Pathology
- Spaceflight effects on biology
- Pain Mechanisms and Treatments
- Spinal Fractures and Fixation Techniques
- Advanced MRI Techniques and Applications
- Mindfulness and Compassion Interventions
- Shoulder Injury and Treatment
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Traumatic Brain Injury Research
- Sports injuries and prevention
- Bone health and osteoporosis research
- Balance, Gait, and Falls Prevention
- Knee injuries and reconstruction techniques
- Musculoskeletal Disorders and Rehabilitation
- Orthopedic Surgery and Rehabilitation
- Tendon Structure and Treatment
- Occupational Health and Performance
- Osteoarthritis Treatment and Mechanisms
- Medical Imaging and Analysis
- Space Exploration and Technology
- Total Knee Arthroplasty Outcomes
- Bone and Joint Diseases
- Atomic and Subatomic Physics Research
University of California, San Diego
2016-2025
VA San Diego Healthcare System
2016-2025
Government of the United States of America
2023
La Jolla Bioengineering Institute
1997-2020
University of California, San Francisco
2015-2019
King Saud University
2019
San Diego State University
2019
American Academy of Neurology
2019
Stanford University
2019
University of Alabama at Birmingham
2017
Several attempts have been made to measure the segmental range of motion in lumbar spine during flexion-extension with purpose gathering additional data for diagnosis instability. The previous studies were performed vitro or vivo active motion. aim this study was obtain normal values passively motions. Forty-one healthy adults examined by means functional radiographs and lateral bending. A graphic construction method a computer-assisted used rotations. Comparing recent studies, obtained...
The purpose of this study was to determine the clinical validity functional flexion-extension roentgenograms lumbar spine in a defined patient population. One hundred and one adults with low-back pain or disorders underwent passive flexionextension examinations. Their were analyzed using computer-assisted method segmental motion parameters such as rotation translation vertebrae. population broken down into five groups similar pathologies physical conditions, their compared normal each other....
Traumatic brain injury (TBI) is a leading cause of sustained impairment in military and civilian populations. However, mild TBI (mTBI) can be difficult to detect using conventional MRI or CT. Injured tissues mTBI patients generate abnormal slow-waves (1–4 Hz) that measured localized by resting-state magnetoencephalography (MEG). In this study, we develop voxel-based whole-brain MEG slow-wave imaging approach for detecting abnormality with on single-subject basis. A normative database source...
Prospective case series.Evaluate lumbar paraspinal muscle (PSM) cross-sectional area and intervertebral disc (IVD) height changes induced by a 6-month space mission on the International Space Station. The long-term objective of this project is to promote spine health prevent spinal injury during missions here Earth.National Aeronautics Administration (NASA) crewmembers have 4.3 times higher risk herniated IVDs, compared with general military aviator populations. highest occurs first year...
A pair of functional radiographs, taken at each end the range motion, are used to determine spinal motions. Graphic construction and computer–assisted methods available for radiographic analysis. The latter provides many more motion parameters. study lumbar spine lateral radiographs was conducted errors in parameters due level, quality, two digitizing instruments. Significant differences were found digitizers when same redigitized several times. There only minimal differences, however,...
Age is a known risk factor for complications after knee arthroplasty; however, age-related risks variety of total and partial arthroplasties have not been well quantified.Our study addressed three questions to better understand complications: (1) At what age do different types increase? (2) Is the increase in with resulting from patient comorbidities, sociodemographic characteristics, surgical conditions? (3) What probability at ages an average patient?The American College Surgeons National...
Fear of falling is an important problem among older adults, even those with relatively low rates objective fall risk, who are often overlooked as targets for intervention.We developed and pilot tested a new intervention, Activity, Balance, Learning, Exposure (ABLE), in sample 10 adults excessive fear falling. The ABLE intervention integrates exposure therapy cognitive restructuring home safety evaluation exercise program conducted the home. In this project, was jointly by physical therapist...
Microgravity-induced lumbar paraspinal muscle deconditioning may contribute to back pain commonly experienced by astronauts and increase the risk of postflight injury. We hypothesized that a combined resistive aerobic exercise countermeasure protocol included spinal loading would mitigate during 60 days bed rest in women. Sixteen women underwent 60-day, 6° head-down-tilt (BR) were randomized into control groups. During group performed no exercise. The supine treadmill within lower body...
For chronic low back pain, the causal mechanisms between pathological features from imaging and patient symptoms are unclear. instance, disc herniations can often be present without symptoms. There remains a need for improved knowledge of pathophysiological that explore spinal tissue damage clinical manifestations pain disability. Spaceflight astronaut health provides rare opportunity to study potential longitudinally. disrupts diurnal loading on spine several lines evidence indicate...
To assess the effect of hyaluronan on meniscus injury and repair, we had 35 mature New Zealand White rabbits undergo bilateral repair (19 in peripheral region, 16 inner region). A longitudinal tear was created medial repaired with horizontally placed nylon sutures. The left knee joint received intraarticular injections 1 week after surgery once a for 5 weeks. right knees were injected phosphate-buffered saline (the carrier vehicle hyaluronan). Twelve weeks tears region showed gross...
Background Research demonstrates that yoga can be effective for improving chronic low back pain (cLBP) among military veterans and non-veterans. Attendance of interventions is necessary to obtain benefits, yet class attendance a challenge both within outside research, especially persons who lack resources. Objective Our objective was describe efforts boost randomized trial cLBP, examine factors related attendance. Methods A previous cLBP randomly assigned participants 2x weekly 12 weeks, or...
Summary of Background Data Although the extant injury after cervical spine fracture can be visualized by imaging, deformations that occur in spinal canal during are unknown. Study Design This study compared occlusion and axial length changes occurring a simulated compressive burst frecture with residual injury. Methods Canal was measured from pressure flexible tube fluid flowing through it, placed space removal cord cadaver specimens. To measure length, cables were fixed C1 led foramen...
Background: Sacroiliac joint (SI) pain is increasingly being recognized as a source of low back pain. Injections and percutaneous type procedures are performed to treat symptomatic joints. However, there limited studies available assessing the anatomy SI in vivo among patients with Objectives: The purpose this study was provide more precise information on dimensions orientation using new technique for radiographic evaluation joint. Study Design: Observational study. Setting: Emergency...
Abstract Ultrashort echo time (UTE) MRI can quantify the major proton pool densities in cortical bone, including total (TWPD), bound (BWPD), and pore water (PWPD) densities, as well macromolecular density (MMPD), associated with collagen content, which is calculated using fraction (MMF) from UTE magnetization transfer (UTE-MT) modeling. This study aimed to investigate differences contents tibial between female osteopenia (OPe) patients, osteoporosis (OPo) young participants (Young). Being...
Because of the violent nature traumatic brain injury, injury patients are susceptible to various types trauma involving auditory system. We report a case 55-yr-old man who presented with communication problems after injury. Initial results from behavioral audiometry and Weber/Rinne tests were not reliable because poor cooperation. He was transferred our service for inpatient rehabilitation, where review initial head computed tomographic scan showed only left temporal bone fracture. Brainstem...