Both depression and cancer are economically burdensome. However, how affects the healthcare expenditures of elderly patients from payers' patients' perspectives is largely unknown. This study investigated whether resulted in higher among these both identified health service use categories associated with increased expenditures.From Medicare Current Beneficiary Survey (MCBS)-Medicare database, we breast, lung prostate aged 65 years over who were newly diagnosed between 2007 2012. Presence was...

Objectives The incidence of neuroendocrine tumors (NETs) has been steadily increasing. Racial differences in the and survival are mostly unknown. This study examines racial underlying causes. Methods We conducted a retrospective, population-based using datasets from Surveillance, Epidemiology, End Results (SEER) cancer registry SEER data linked with Medicare claims (SEER-Medicare). examined rates effects patient demographics, clinical characteristics, socioeconomic factors on survival. Of...

Abstract Background The influence of serious mental illness (SMI) on the treatment and survival patients with high‐grade prostate cancer is not well understood. We compared initial cancer‐specific mortality SEER‐Medicare locoregional (nonmetastatic) without preexisting SMI. Methods identified who were 67 years age or older diagnosed between 2006 2013 cancer. Preexisting SMI was by claims indicative bipolar disorder, schizophrenia, other psychotic during 2 before diagnosis. used multivariable...

The latest published CASPIAN trial demonstrated that adding durvalumab to etoposide and platinum (EP) improved survival dramatically for patients with extensive-stage small cell lung cancer (ES-SCLC). Considering the high cost of durvalumab, this study evaluated cost-effectiveness plus EP (DEP) in first-line setting treatment-naïve ES-SCLC from U.S. payer perspective.We developed a three-state Markov model simulate disease course source consumption over lifetime horizon. Pseudo-individual...

Importance Cigarette smoking is a primary risk factor for chronic lower respiratory disease (CLRD) and associated with worse symptoms among people CLRD. It important to evaluate the economic outcomes of in this population. Objective To estimate prevalence cigarette smoking-attributable health care expenditures (SAHEs) adults CLRD US. Design, Setting, Participants This cross-sectional study used data from 2014-2018 2020 National Health Interview Surveys (NHIS) Medical Expenditure Panel...

This study examined the patterns of prolonged opioid use and factors associated with higher risk among opioid-naïve working-age patients early-stage breast cancer.Using MarketScan data, identified 23,440 who received surgery for cancer between January 2000 December 2014 filled at least one prescription attributable to surgery. Prolonged was defined as or more prescriptions opioids within 90 180 days after extra-prolonged 181 365 Multivariable logistic regressions were performed ascertain...

Abstract The incidence and prevalence of neuroendocrine tumors (NETs) are continually increasing. While it is known that NET symptoms often predate diagnosis, their impact on resource utilization costs largely unknown. We identified 9,319 elderly patients diagnosed with NETs between 1/2003 12/2011 from the Surveillance, Epidemiology End Results (SEER)-Medicare. examined patients’ conditions potentially associated NET, during year before diagnosis. found were more likely to have diagnoses...

Introduction Previous research quantifying the relationship between tobacco use and food insecurity has focused on cigarette smoking. E-cigarette become popular in recent years. Drawing large, population-based survey data, this study augments previous research, considering association of e-cigarette with among low-income adults. Methods We analysed data from California Health Interview Survey 2014–2019. The sample consisted 25 948 respondents aged 18–64 who lived (<200% Federal Poverty...

How depression affects the medication cost burden for elderly cancer survivors has not been well studied. This study aims to investigate whether is associated with higher rates of cost-related nonadherence, and cost-reduction strategies among survivors. Self-reports from survey files 2015 Medicare Current Beneficiary Survey-Medicare database were used identify patients aged 65 years older without depression. The 2 outcomes nonadherence (CRN) adoption strategies. Bivariate analysis was...

Background. Robotic surgical systems are expensive to own and operate, the purchase of such technology is an important decision for hospital administrators. Most prior literature focuses on comparison clinical outcomes between robotic surgery other laparoscopic or open surgery. There a knowledge gap about what drives hospitals' decisions systems. Objective. To identify factors associated with hospital's acquisition advanced Method. We used 2002 2011 data from State California Office...

Although modern automatic speech recognition (ASR) systems can achieve high performance, they may produce errors that weaken readers' experience and do harm to downstream tasks. To improve the accuracy reliability of ASR hypotheses, we propose a cross-modal post-processing system for recognizers, which 1) fuses acoustic features textual from different modalities, 2) joints confidence estimator an error corrector in multi-task learning fashion 3) unifies correction utterance rejection...

Deep learning has becoming increasingly more popular in recent years, and there are many frameworks the market accordingly, such as Caffe, TensorFlow Pytorch. All these natively support CPUs GPGPUs. However, FPGAs still cannot provide a comprehensive by for deep development, especially training phase. In this paper, we firstly propose FeCaffe, i.e. FPGA-enabled hierarchical software hardware design methodology based on to enable FPGA CNN features. Moreover, some benchmarks of networks with...

Prevalence of smoking is high among patients receiving care in safety-net settings, and there a need to better understand patient factors associated with cessation receipt services.

Abstract Purpose To investigate the cost‐effectiveness of lenvatinib plus pembrolizumab (LP) compared to chemotherapy as a second‐line treatment for advanced endometrial cancer (EC) from United States and Chinese payers' perspective. Methods In this economic evaluation, partitioned survival model was constructed perspective payers. The data were derived clinical trial (309‐KEYNOTE‐775), while costs utility values sourced databases published literature. Total costs, quality‐adjusted life...

In the healthcare sector, application of deep learning technologies has revolutionized data analysis and disease forecasting. This is particularly evident in field diabetes, where Electronic Health Records (EHR) unlocked new opportunities for early detection effective intervention strategies. Our research presents an innovative model that synergizes capabilities Bidirectional Long Short-Term Memory Networks-Conditional Random Field (BiLSTM-CRF) with a fusion XGBoost Logistic Regression....

Abstract Introduction On April 1, 2017, California Proposition 56 (Prop 56) was implemented, increasing the excise tax on cigarettes by $2/pack. This study compares association of Prop with smoking prevalence and intensity across racial/ethnic groups, further examining distinctions income subgroups within each group. Aims Methods The used pooled cross-sectional data from 2012–2018 Behavioral Risk Factor Surveillance System. We examined two outcomes: current conditional smoking. A two-part...

Background: Life expectancy for patients with malignant tumors has been significantly improved since the presence of programmed cell death protein-1/programmed protein ligand-1 (PD-1/PD-L1) inhibitors in 2014, but they impose heavy financial burdens patients, healthcare system and nations. The objective this study was to determine survival benefits, toxicities, monetary quantify their values. Methods: Randomized controlled trials (RCTs) PD-1/PD-L1 were identified clinical benefits quantified...

Abstract STUDY QUESTION Is it economically worthwhile to use GnRH agonist (GnRHa) prevent menopausal symptoms (MS) and protect fertility in premenopausal women with breast cancer (BC) during chemotherapy from the US perspective? SUMMARY ANSWER It is cost-effective administer GnRHa order forefend MS patients BC when willingness-to-pay (WTP) threshold $50 000.00 per quality-adjusted life-year (QALY), preserve young who undergo oocyte cryopreservation (OC), or no OC, WTP thresholds live birth...

BACKGROUND: Multiple myeloma survival rates are steadily increasing due to availability of new drug classes used in combination with corticosteroids and chemotherapy. The latest treatments daratumumab or bortezomib therapy lenalidomide dexamethasone (Rd). Daratumumab, a CD38-targeted, human IgG1k monoclonal antibody, bortezomib, proteasome inhibitor, both approved as regimens for transplant-ineligible relapsed/refractory multiple (RRMM). There have been cost-effectiveness analyses use RRMM,...