A5036762565- Hematopoietic Stem Cell Transplantation
- Chronic Lymphocytic Leukemia Research
- Acute Myeloid Leukemia Research
- Multiple Myeloma Research and Treatments
- Lymphoma Diagnosis and Treatment
- Chronic Myeloid Leukemia Treatments
- Neutropenia and Cancer Infections
- Hemoglobinopathies and Related Disorders
- Acute Lymphoblastic Leukemia research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Hematological disorders and diagnostics
- Blood groups and transfusion
- Blood disorders and treatments
- Complement system in diseases
- Iron Metabolism and Disorders
- Viral-associated cancers and disorders
- Immunotherapy and Immune Responses
- Peptidase Inhibition and Analysis
- Immunodeficiency and Autoimmune Disorders
- Eosinophilic Disorders and Syndromes
- Polyomavirus and related diseases
- Childhood Cancer Survivors' Quality of Life
- RNA Interference and Gene Delivery
- Testicular diseases and treatments
- Mycobacterium research and diagnosis
Erciyes University
2016-2025
Izmir Institute of Technology
2024
Erciyes Üniversitesi Tıp Fakültesi Hastaneleri
2024
Centre Hospitalier Universitaire de Nantes
2023
Weatherford College
2023
Wroclaw Medical University
2023
Children's Hospital
2023
Poznan University of Medical Sciences
2023
Hospital Universitario La Paz
2023
Universidad Autónoma de Madrid
2023
Cyclophosphamide (Cy) combined with total-body irradiation (TBI) or busulfan (Bu) are currently the most common myeloablative regimens used in allogeneic stem-cell transplantation (alloSCT) adults acute myelogenous leukemia (AML). Intravenous (IV) Bu has more predictable bioavailability and a safer toxicity profile than oral formulation. Comparative studies of outcomes have been performed between Bu/Cy Cy/TBI, but there no comparative trials era IV Bu.We retrospective registry-based study...
We have analyzed 1448 patients with acquired aplastic anemia grafted between 2005 and 2009, compared outcome of identical sibling (n=940) versus unrelated donor (n=508) transplants. When to the latter, transplants were less likely be performed beyond 180 days from diagnosis (39% vs. 85%), a cytomegalovirus negative donor/recipient status (15% 23%), receive antithymocyte globulin in conditioning (52% 61%), more frequently received marrow as stem cell source (60% 52%). Unrelated grafts had...
MABLE investigated the efficacy and safety of rituximab plus bendamustine or chlorambucil in fludarabine-ineligible patients with chronic lymphocytic leukemia. Patients received every four weeks for six cycles. Rituximab chlorambucil-treated without a complete response after Cycle 6 monotherapy at least additional cycles until response. The primary endpoint was rate (confirmed by bone marrow biopsy) first-line patients. Secondary endpoints included progression-free survival, overall minimal...
Here, we report the outcome of 226 myeloma patients presenting with extramedullary plasmacytoma or paraosseous involvement in a retrospective study conducted 19 centers from 11 countries. Extramedullary disease was detected at diagnosis relapse between January 2010 and November 2017. were observed 130 (92 38) 96 (84 12). The median time multiple to development 25.1 months (range 3.1-106.3 months) group (median follow up: 15 months). Imaging approach for computed tomography (n=133), positron...
Abstract The aim of the study is to review clinical manifestations and hematological findings brucellosis pancytopenia, with or without malignancies. records 202 patients were evaluated retrospectively. Among these cases seen in a 6 year period between April 1999 June 2005, 30 pancytopenia identified. most common manifestation was fever, followed by weight loss, anorexia, malaise, arthralgia, hepatosplenomegaly. Bone marrow biopsies revealed hypercellularity normocellularity. bone evaluation...
Plasma exchange therapy has been successfully used in selected patients with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome who have organ failure or refractory to treatment. There is no prospective study regarding plasma its effect HELLP syndrome. The aim of this was investigate the effects early postpartum use on outcomes. mortality rate recovery times were compared treated historic control group conservatively. During a 3-year period (between April 2000 December...
Conditioning regimens used during stem cell transplant provide prolonged control or cure of the disease in patients with acute lymphoblastic leukemia (ALL). In this study, we present a comparison treatment results for 95 ALL who underwent allogeneic hematopoietic (AHSCT) total body irradiation plus cyclophosphamide (TBI + Cy) busulfan (Bu as conditioning regimen. Median age was 25 (range: 9-54) years. follow-up 24 3-107) months. overall survival (OS) found to be 29 event-free (EFS) 9 OS 37...
The use of αβ+ T-cell-depleted grafts is a novel approach to prevent graft failure, graft-versus-host disease (GVHD), and non-relapse mortality (NRM) in patients undergoing haploidentical hematopoietic stem cell transplantation.Thirty-four with acute leukemia lacking match donor were treated αβ allografts from family donors. A total 24 had myeloid (AML) 10 lymphoblastic leukemia. 84.4% the high-risk group, 55.9% not remission. preparative regimen included thiotepa, melphalan, fludarabine,...
Hemophagocytic lymphohistiocytosis (HLH) is an immune disorder with high mortality due to uncontrolled activation of T lymphocytes and macrophages excessive proliferation inflammatory cytokines. A 37-year-old female patient diagonsed primary HLH presented here. The was hospitalized complaints fever, weakness, joint pain. pancytopenic, had ferritin low fibrinogen. She hepatosplenomegaly. bone marrow biyopsy pathology result consistent hemophagocytosis. patient's NK cytotoxicity low. As a the...
Abstract Introduction Therapeutic thrombocytapheresis (TTA) is used to promptly reduce platelet count prevent thrombohemorrhagic complications that may develop in extreme thrombocytosis. In this study, the efficacy and safety of TTA were investigated our patients who underwent for thrombocytosis more than 20 years. Materials Methods Forty‐four due between January 2000 December 2021 Erciyes University, Faculty Medicine Apheresis Unit analysed retrospectively. Extreme was defined as a >1000...
Iron overload increases the risk of infections, veno-occlusive disease and hepatic dysfunction in post-transplant period. Our objective was to investigate association pre-transplant ferritin levels with complications survival after allogeneic hematopoietic stem cell transplantation (alloHSCT).We retrospectively analysed 84 patients' data who had undergone HSCT into two groups: patients a serum level ≥ 1000 ng/ml, <1000 ng/ml at time HSCT.Cox-regression analysis showed that were significantly...