Haining Zhang

ORCID: 0000-0001-7032-2695
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About
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Research Areas
  • Total Knee Arthroplasty Outcomes
  • Orthopaedic implants and arthroplasty
  • Orthopedic Infections and Treatments
  • Erythrocyte Function and Pathophysiology
  • Osteoarthritis Treatment and Mechanisms
  • RNA Interference and Gene Delivery
  • Lower Extremity Biomechanics and Pathologies
  • Reconstructive Surgery and Microvascular Techniques
  • Inflammasome and immune disorders
  • Blood transfusion and management
  • Facial Trauma and Fracture Management
  • Plant Molecular Biology Research
  • Plant Reproductive Biology
  • Exercise and Physiological Responses
  • Venous Thromboembolism Diagnosis and Management
  • Reconstructive Facial Surgery Techniques
  • Cancer-related molecular mechanisms research
  • Plant biochemistry and biosynthesis
  • RNA Research and Splicing
  • Immune Response and Inflammation
  • Ferroptosis and cancer prognosis

Qingdao University
2023-2025

Affiliated Hospital of Qingdao University
2023-2025

Shandong Normal University
2024

Sun Yat-sen Memorial Hospital
2016

Sun Yat-sen University
2016

This study aimed to (1) determine the association between varus knee deformity and ipsilateral foot ankle morphology, (2) evaluate relationship pain in patients with end-stage osteoarthritis (KOA). A total of 213 who underwent primary arthroplasty for KOA were enrolled this divided into a 'severe group' (n = 119) 'mild 94) based on preoperative degree. Morphological parameters incidence compared two groups. The correlation morphology was analyzed. Significant differences observed magnitudes...

10.1186/s13018-024-05433-0 article EN cc-by-nc-nd Journal of Orthopaedic Surgery and Research 2025-01-07

With the increasing prevalence of obesity, there is growing awareness impact overweight and obesity on total hip arthroplasty (THA). Research exploring accuracy acetabular component orientation in THA between robotic-assisted manual techniques across different BMI categories insufficient.

10.1186/s13018-024-05117-9 article EN cc-by-nc-nd Journal of Orthopaedic Surgery and Research 2024-10-08

Abstract Osteoarthritis (OA), characterized by progressive cartilage degeneration and chronic joint pain, represents a major global health challenge. While intra‐articular drug delivery is common therapeutic approach, its efficacy limited poor penetration through the dense matrix, particularly for hydrophobic compounds. Here, novel charge‐guided micro/nanocarrier system designed to overcome these challenges presented. By modifying amylose with glycidyl trimethyl ammonium chloride (GTAC), it...

10.1002/adfm.202422280 article EN cc-by Advanced Functional Materials 2025-01-29

Intra-articular drug injection is an effective treatment for osteoarthritis (OA). However, the rapid clearance of drugs from joint cavity results in low utilization and suboptimal therapeutic outcomes. This study describes MXene-based cartilage-adhesive microspheres photothermal-controlled hydrophobic release bone marrow mesenchymal stem cell (BMSC) delivery. Nano cationic amylose (NCA) was obtained by modifying with glycidyltrimethylammonium chloride (GTAC), Kartogenin (KGN) encapsulated...

10.1021/acsnano.4c16918 article EN ACS Nano 2025-05-30

Leg length discrepancy (LLD) is a common complication of total hip arthroplasty (THA). However, the relationship between femoral prosthesis filling, proximal morphology, and acetabular positioning with postoperative LLD clinical outcomes unclear. The aims this study were to investigate influence canal flare index (CFI), fill ratio (CFR), center rotation (COR), offset (FO) on (1) LLD; (2) in two stem designs different coating distribution.The cohort included 161 patients who underwent primary...

10.1186/s13018-023-03847-w article EN cc-by Journal of Orthopaedic Surgery and Research 2023-06-05

Controlling organ size in plants is a complex biological process influenced by various factors, including gene expression, genome ploidy, and environmental conditions. Despite its importance for plant growth development, the mechanisms underlying regulation remain unknown. Here, we investigated role of RAN1, member Ras-related nuclear GTPases family, regulating pollen size. A RAN1 knockdown mutant (ran1-1) exhibited significant reduction size, accompanied impaired germination reduced tube...

10.1242/jcs.261920 article EN publisher-specific-oa Journal of Cell Science 2024-11-29

Abstract Purpose The risk factors for excessive blood loss and transfusion during total knee arthroplasty (TKA) remain unclear. present study aimed to determine the establish a predictive model postoperative transfusion. Methods This retrospective included 329 patients received TKA, who were randomly assigned training set ( n = 229) or test 100). Univariate multivariate linear regression analyses used loss. logistic R software was prediction model. accuracy stability of models evaluated...

10.1186/s12891-024-07570-3 article EN cc-by BMC Musculoskeletal Disorders 2024-06-10

<title>Abstract</title> Background This study employed a novel method to measure radiographic anteversion (RA) of acetabular cups following total hip arthroplasty (THA) and validated its accuracy in comparison traditional methods. The new involves measuring anatomical (AA) using CT scans inclination (RI) from anteroposterior (AP) radiographs, followed by calculating RA through mathematical function. Methods imaging data 152 patients (192 hips) post-THA were retrospectively assessed twice for...

10.21203/rs.3.rs-4862348/v1 preprint EN Research Square (Research Square) 2024-09-12

Total hip revision with osseous defects can be very difficult. Artificial intelligence offers preoperative planning, real-time measurement, and intraoperative judgment, which guide prothesis placement more accurately. Three-dimensional printed metel augment modules are made according to the individualized anatomy, fit well provide mechanical support. In this case, we used AI plan size position of acetabular cup 3D-printed augmented in a complicated an bone defects, achieved stable fixation...

10.3389/fsurg.2023.1237075 article EN cc-by Frontiers in Surgery 2023-09-19
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