A5057288959- Neuroendocrine Tumor Research Advances
- Neurofibromatosis and Schwannoma Cases
- Sarcoma Diagnosis and Treatment
- Soft tissue tumor case studies
- Pituitary Gland Disorders and Treatments
- Adrenal and Paraganglionic Tumors
- Neuroblastoma Research and Treatments
- Chromatin Remodeling and Cancer
- Ureteral procedures and complications
- Parathyroid Disorders and Treatments
- Tissue Engineering and Regenerative Medicine
- Thyroid and Parathyroid Surgery
- Gastrointestinal disorders and treatments
- Ear and Head Tumors
- Bacterial biofilms and quorum sensing
- Adrenal Hormones and Disorders
- Liver Disease and Transplantation
- Ovarian cancer diagnosis and treatment
- Lung Cancer Research Studies
- Intraperitoneal and Appendiceal Malignancies
- Soft tissue tumors and treatment
- Pressure Ulcer Prevention and Management
- Genetic Syndromes and Imprinting
- Thyroid Cancer Diagnosis and Treatment
- Graphene and Nanomaterials Applications
The University of Texas MD Anderson Cancer Center
2019-2025
Louisiana State University Health Sciences Center New Orleans
2019-2023
Louisiana State University Agricultural Center
2013
<h3>Importance</h3> Neurofibromatosis type 1 (NF1) is a complex genetic disorder that associated with not only neurofibromas, but also an increased susceptibility to other neoplasms. <h3>Objective</h3> To evaluate the prevalence of neoplasia and outcomes among patients NF1. <h3>Design, Setting, Participants</h3> This cohort study was conducted NF1 at single academic cancer center from 1985 2020 median (range) follow-up 2.9 years (36 days 30.5 years). Of 2427 evaluated for NF1, 1607 who met...
Abstract Background Multiple Endocrine Neoplasia Type 1 (MEN1) is an autosomal dominant disorder that predisposes individuals to endocrine tumours, including pancreatic neuroendocrine tumours (PNETs), which range from indolent metastatic. Liver metastases occur in up 80% of high-grade and 30% low-grade well-differentiated PNETs, contributing significantly mortality. Predicting metastatic progression critical for timely surgical intervention, yet clinical tools such predictions remain...
Aim: To determine if porcine urinary bladder matrix (UBM) treatment is associated with modulation of wound inflammation in diabetic patients. Patients & methods: mRNA M1 and M2 macrophages were measured wounds nondiabetic patients pre- post-treatment UBM an M1:M2 score was calculated. Results: Wound tissue from subjects exhibited elevated scores compared patients, suggesting a greater pro-inflammatory state prior to treatment. Post-treatment, there significantly reduction the magnitude...
Background The objective of this study was to evaluate treatment outcomes for patients with desmoid tumors (DTs) receiving local therapy surgery alone, radiation (RT) or combined modality (RT and surgery). Methods This a cross‐sectional cohort 412 nonmesenteric DTs who received at the authors' institution between 1965 2018. Results median follow‐up time 95 months (range, 1‐509 months). Local recurrence occurred in 127 (31%) 21 (interquartile range, 12‐38 5‐year control (LC) rate 67%. Patient...
Herein we report a facile layer-by-layer method for creating an antimicrobial coating composed of silver nanoparticles on medical grade titanium test discs. Nanoscale nanoparticle layers are attached to the orthopedic implant material via aminopropyltriethoxy silane crosslinker that reacts with neighboring moieties create interconnected network. A monolayer silane, followed by would form one self-assembled layer and this process can be repeated serially, resulting in increased deposition....
ABSTRACT Malignant peripheral nerve sheath tumor (MPNST) development is characterized by an altered DNA methylation landscape, which presents a promising area for developing MPNST‐specific biomarkers screening patients with NF1. Genome‐wide profiling of cohort 13 MPNST (29 samples and adjacent neurofibroma tissues) NF1‐MPNST cell lines was performed to identify validate candidate CpG sites (CpGs). A logistic regression prediction model constructed select CpGs distinct from neurofibromas...
Abstract Malignant peripheral nerve sheath tumors (MPNSTs) are a highly aggressive soft tissue sarcoma affecting approximately 10-15% of individuals with neurofibromatosis type 1 (NF1). MPNST development is characterized by an altered DNA methylation landscape and presents promising area for developing MPNST-specific biomarkers screening NF1 patients in the clinic. Here, using genome-wide profiling cohort 13 matched pairs MPNSTs adjacent neurofibroma tissues, along cell lines control...