A5100393548- Polysaccharides and Plant Cell Walls
- Gut microbiota and health
- RNA Interference and Gene Delivery
- Hydrogels: synthesis, properties, applications
- Bioactive Compounds in Plants
- Seaweed-derived Bioactive Compounds
- Advanced biosensing and bioanalysis techniques
- Electrospun Nanofibers in Biomedical Applications
- Helicobacter pylori-related gastroenterology studies
- Phytochemicals and Antioxidant Activities
- Autophagy in Disease and Therapy
- Fungal Biology and Applications
- Polysaccharides Composition and Applications
- Free Radicals and Antioxidants
- Tea Polyphenols and Effects
- Wound Healing and Treatments
- Inflammasome and immune disorders
- Biological Activity of Diterpenoids and Biflavonoids
- Food composition and properties
- Drug Transport and Resistance Mechanisms
- Nanocomposite Films for Food Packaging
- Selenium in Biological Systems
- Silk-based biomaterials and applications
- Tannin, Tannase and Anticancer Activities
- Inflammatory Bowel Disease
Southern Medical University
2017-2024
South China University of Technology
2014-2019
Jinan University
2015-2017
Bioscience (China)
2017
University of Saskatchewan
2016
Utah AIDS Foundation
2016
A novel polysaccharide, here named DP1, was isolated from the fruiting body of Dictyophora indusiata using a water extraction method. Structure characterization revealed that DP1 had an average molecular weight 1132 kDa and consisted glucose (56.2%), galactose (14.1%), mannose (29.7%). The main linkage type were proven to be (1 → 3)-linked α-l-Man, 2,6)-linked α-d-Glc, 6)-linked β-d-Glc, β-d-Gal, β-d-Man by periodate oxidation–Smith degradation nuclear magnetic resonance analysis....
The intracellular antioxidant activities of diosmetin were evaluated by cellular activity (CAA) assay, 2,2-azobis(2-amidinopropane) dihydrochloride (AAPH)-induced erythrocyte hemolysis assay and cupric chloride (CuCl2)-induced plasma oxidation assay. results showed that exhibits strong (EC50 = 7.98 μmol, CAA value 58 μmol QE/100 μmol). It was also found treatment could effectively attenuate AAPH-induced (91.0% inhibition at 100 μg/mL) CuCl2-induced through reactive oxygen species (ROS)...
Abstract Bio-functionalized nanoparticles with semiconducting/metallic core encapsulated in a bio- or bio-derived materials are promising for applications biology and especially cancer diagnostic healing. In this report, we report facile, single-step, first-time synthesis in-situ functionalization strategy the preparation of monodispersed selenium (SeNPs) functionalized using novel polysaccharide (DP1) extracted from Dictyophora indusiata (a fungus). The DP1 SeNPs (DP1-SeNPs), where is...
Ovarian cancer is one of the most serious female malignancies worldwide. Despite intensive efforts being made to overcome ovarian cancer, there still remain limited optional treatments for this disease. Nobiletin, a prospective food-derived phytochemical extracted from citrus fruits, has recently been reported suppress cells, but role pyroptosis in carcinoma with nobiletin remains unknown. In study, we aim explore effect on and further expound underlying mechanisms nobiletin-induced cell...
Dictyophora indusiata polysaccharide (DP1) was successfully chelated with zinc chloride to achieve its enhanced antiproliferative activity. The obtained DP1-Zn complex showed significant activity (18.1 ± 2.84% viability of MCF-7 cells at 250 μg/mL) on a group human cancer cell lines through induction apoptosis. pro-apoptotic action confirmed by morphological changes including chromatin condensation, DNA breakage, and S phase cycle arrest in breast adenocarcinoma (MCF-7). DP1-Zn-induced...
The walnut peptides and zinc ions were combined to generate a peptides-zinc complex (WP1-Zn) with enhanced antiproliferative ability as well reduced toxicity. result indicated that Zn successfully WP1 through Zn–N Zn–O covalent bonds. WP1-Zn compounds exhibited strong against the selected human cell lines, especially MCF-7 cells, whose survival rate 20.02% after exposure 300 μg/mL of for 48 h. inhibited proliferation inducing apoptosis cycle arrest. results induced via ROS triggered...
A polysaccharide fraction, here called POP1, was purified from the leaves of Platycladus orientalis (L.) Franco by water extraction and alcohol precipitation. Physicochemical characterization indicated that POP1 had a relative molecular weight 8.10 × 10(3) Da consisted rhamnose (5.74%), arabinose (12.58%), mannose (10.97%), glucose (64.96%), galactose (6.55%). The main linkage types (1→5)-linked α-l-Ara, (1→3)-linked α-l-Man, (1→6)-linked β-l-Rha, (1→4)-linked α-d-Glc, β-d-Gal,...
Hydrogel is a new class of functional polymer materials with promising potential in the biomedical field. The purpose this article to review recent advancements several types hydrogels, including conductive injectable double network responsive nanocomposite and sliding hydrogels. In comparison traditional these advanced hydrogels exhibit significant advantages structure, mechanical properties, applications. focuses on different methods used prepare their diversified applications as drug...
Lots of active substances are hydrophobic materials at ambient and body temperatures, decreasing their bioavailability posing great challenges to successful incorporation into medication functional foods. The goal this research was develop a nanoemulsion delivery system containing crystalline bioactive component (nobiletin) improve the anti-inflammatory activity. Nobiletin incorporated oily phase, nanoemulsions were fabricated using high-speed high-pressure homogenization. Particle size,...
The flavonoids (POFs) from the leaves of Platycladus orientalis (L.) Franco were purified using six different macroporous adsorption resins including polar NKA-9 and ADS-F8, semi-polar ADS-17 AB-8, non-polar D101 ADS-5. Among resins, AB-8 demonstrated best desorption capacities with an ratio 86% a 52%. According to Simultaneous Thermogravimetry-Differential Scanning Calorimetry (STA/TG-DSC) analysis, POFs showed three thermally decomposed temperatures (347.6 °C, 437.5 °C 494.8 °C). main in...
Andrographis paniculata Nees is used as a functional food in Japan, Korea, India, and China. Andrographolide, naturally occurring phytochemical identified paniculata, has been discovered to present anti-inflammatory anticancer activities. Highly expressed interleukin (IL-8) detected colorectal cancer implicated angiogenesis. However, the effect molecular mechanisms of IL-8 expression by andrographolide remain obscure human cells. The study was aimed investigate effects on TNF-α-induced its...