Mehmet İşler

ORCID: 0000-0001-7215-367X
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Research Areas
  • Helicobacter pylori-related gastroenterology studies
  • Gastroesophageal reflux and treatments
  • Liver Disease Diagnosis and Treatment
  • Hepatitis C virus research
  • Probiotics and Fermented Foods
  • Cardiovascular Function and Risk Factors
  • Esophageal and GI Pathology
  • Cardiovascular Disease and Adiposity
  • Abdominal vascular conditions and treatments
  • Trace Elements in Health
  • Hepatitis B Virus Studies
  • Gastrointestinal disorders and treatments
  • Pathogenesis and Treatment of Hiccups
  • Pediatric Hepatobiliary Diseases and Treatments
  • Gallbladder and Bile Duct Disorders
  • Health, Medicine and Society
  • Pancreatitis Pathology and Treatment
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Palliative Care and End-of-Life Issues
  • Liver Diseases and Immunity
  • Dermatoglyphics and Human Traits
  • Tuberculosis Research and Epidemiology
  • Foreign Body Medical Cases
  • Helminth infection and control
  • Intracerebral and Subarachnoid Hemorrhage Research

Süleyman Demirel University
2000-2019

Suleyman Demirel University
2007-2016

Triemli Hospital
2014

Suleyman Demirel University Research and Education Hospital
2010

Ege University
1994

Izmir University
1993

The systemic effects of bioactive peptides which are produced by the fermentation milk via microorganisms found in kefir have been subject interest recent years. Bioactive activate innate immunity stimulating macrophages, increasing phagocytosis, augmenting NO and cytokine production boosting lumen levels IgG IgA+ B-lymphocytes. aim present study was to determine serum profiles healthy volunteers after consumption evaluate helper T (TH) cell polarization bring out on native allergic immune...

10.5578/mb.4709 article EN Mikrobiyoloji Bulteni 2013-04-26

Abstract Evidence suggests that gut microbiota dysbiosis plays a critical role in the initiation and promotion of inflammatory bowel disease (IBD). Kefir is fermented dairy product including yeast bacterial species. We aimed to investigate effect kefir on trinitrobenzene sulfonic acid (TNBS)‐induced colitis rats using two different doses. Fifty‐four Wistar were divided into six groups. For 14 days, normal control groups given tap water, kefir10 control, colitis, kefir30 phosphate‐buffered...

10.1002/fsn3.1174 article EN cc-by Food Science & Nutrition 2019-08-22

Intestinal bacteria induce endogenous signals that play a pathogenic role in hepatic insulin resistance and non-alcoholic fatty liver disease. Probiotics could modulate the gut flora influence gut-liver axis. We aimed to investigate preventive effect of two probiotic mixtures on methionine choline-deficient diet-induced steatohepatitis model rats.Two studies, short-term (2 weeks) long-term (6 weeks), were carried out using 60 male Wistar rats. The 2-week study included six groups. Rats fed...

10.4318/tjg.2012.0330 article EN The Turkish Journal of Gastroenterology 2012-04-01

We aimed to investigate the role of a probiotic mixture, including 13 different bacteria, in prevention aspirin-induced gastric mucosal injury.Forty rats were allocated into 4 groups: normal control, aspirin, and plus aspirin. Normal control aspirin groups received 0.2 ml skim milk by daily gavage for 14 days. Probiotic administered ml/day mixture (1.3 x 10(10) cfu/ml) suspended On day 15, lesions induced administration (200 mg/kg) groups. given saline.Pretreatment with reduced damage scores...

10.4318/tjg.2011.0151 article EN The Turkish Journal of Gastroenterology 2011-02-01

The protective effect of a probiotic mixture 13 different bacteria and α-tocopherol on 98% ethanol-induced gastric mucosal injury was evaluated. Levels pro- anti-inflammatory cytokines, malondialdehyde, secretory immunglobulin A were measured. Rats allocated into four groups: control, ethanol, probiotic, α-tocopherol. control ethanol groups received skim milk for 14 days. Probiotic administered suspended in 100 mg/kg α-tocopherol, respectively, by daily gavage On Day 15, lesions induced...

10.1089/jmf.2010.0040 article EN Journal of Medicinal Food 2011-01-01

10.1016/j.jiph.2012.11.010 article EN publisher-specific-oa Journal of Infection and Public Health 2013-03-01

10.1016/s0895-6111(02)00023-x article EN Computerized Medical Imaging and Graphics 2003-03-14

10.1097/maj.0b013e3181cf0472 article EN The American Journal of the Medical Sciences 2010-03-24

10.1093/milmed/166.3.203a article EN Military Medicine 2001-03-01

Brucellosis may lead to complications that affect different organ systems, including the liver and spleen. In acute disease, hepatosplenic abscess is a rare complication. We report herein woman with splenic due Brucella melitensis infection who was successfully treated antibiotics alone.

10.1080/00365540110077335 article EN Scandinavian Journal of Infectious Diseases 2002-01-01

10.1097/maj.0b013e3180318da1 article EN The American Journal of the Medical Sciences 2007-03-01

Abstract Purpose. To describe the sonographic findings of biliary fascioliasis. Method. The study included 27 patients with fascioliasis and abdominal in system. All diagnoses were confirmed via serologic enzyme‐linked immunosorbent assay, 5 underwent cholecystectomy. Sonographic system defined as primary secondary. Results. Primary spontaneously moving echogenic structures, linear echoes, curvilinear oval‐shaped structure, matted particle, particle adherent to gallbladder wall, motionless...

10.1002/jcu.20513 article EN Journal of Clinical Ultrasound 2008-07-18

FibroTest and ActiTest are noninvasive tests used in determining the level of fibrosis degree necroinflammatory activity liver. In our study, we aimed to investigate whether these could be alternative liver biopsy.Fifty patients were included study. Serum samples obtained needle biopsy was performed on same day. Levels levels ActiTest, both determined via serum biochemical markers, compared with histopathological examination. For statistical analyses, Mc Nemar chi square test Spearman's...

10.4103/0377-4929.68281 article EN Indian Journal of Pathology and Microbiology 2010-01-01

The Helicobacter pylori (H. pylori) load in both stomach and stool the resulting severity of gastritis are important criteria validating status H. infection. We aimed to assess reliability antigen (HpSA) test for primary diagnosis infection by calculating best cut-off value obtain highest sensitivity specificity dyspeptic patients. also investigated correlation HpSA with load. statuses 95 patients were evaluated positivity rapid urease microscopic detection biopsy specimens, 88 subjects whom...

10.1620/tjem.212.159 article EN The Tohoku Journal of Experimental Medicine 2007-01-01

Dry cough and optic neuritis: two rare complications of interferon α treatment in chronic viral hepatitis *

10.1016/s0002-9270(01)02290-0 article EN The American Journal of Gastroenterology 2001-04-01

In this study, 4 cases of poisoning by wild mushrooms collected from Burdur province are reported. The specimens have been identified as Entoloma clypeatum (L.) P.Kumm. examination their morphology and spores. A description the taxon presented.

10.3906/bot-1007-36 article EN TURKISH JOURNAL OF BOTANY 2011-01-01

We report a case of hepatobiliary fascioliasis presenting with unusual radiological findings that have not been reported previously. Imaging studies revealed hepatic cystic pouches communicating intrahepatic bile ducts. Snail-like, oval shaped and conglomerated echogenic particles no acoustic shadowing, suggesting F. hepatica, were detected in these pouches. In addition, secondary sclerosing cholangitis developed after fascioliasis.

10.4261/1305-3825.dir.2350-08.1 article EN Diagnostic and Interventional Radiology 2009-01-01

Thromboembolic events are rare in the course of ulcerative colitis and related with activity disease. These complications especially seen young patients cause high mortality morbidity. Arterial thrombotic less frequent usually after a surgical procedure. Here, we present 36-year-old man active presenting via digital arterial thrombosis necrosis that was not associated

10.5152/tjg.2014.4025 article EN The Turkish Journal of Gastroenterology 2014-05-21
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