- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Total Knee Arthroplasty Outcomes
- Peripheral Artery Disease Management
- Venous Thromboembolism Diagnosis and Management
- Knee injuries and reconstruction techniques
- Hepatocellular Carcinoma Treatment and Prognosis
- Renal and Vascular Pathologies
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Cerebrovascular and Carotid Artery Diseases
- Vascular anomalies and interventions
- Cardiac Imaging and Diagnostics
- Osteoarthritis Treatment and Mechanisms
- Quantum Information and Cryptography
- Quantum Computing Algorithms and Architecture
- Uterine Myomas and Treatments
- Gallbladder and Bile Duct Disorders
- Orthopedic Infections and Treatments
- Advanced Neuroimaging Techniques and Applications
- Cardiac Arrhythmias and Treatments
- Genetic and Kidney Cyst Diseases
- Atomic and Subatomic Physics Research
- Pancreatic and Hepatic Oncology Research
- Orthopaedic implants and arthroplasty
Google (United Kingdom)
2023-2024
DeepMind (United Kingdom)
2023-2024
Thomas Jefferson University Hospital
2001-2023
Victoria Hospital
2022
Edinburgh Royal Infirmary
2020-2021
NHS Fife
2019
Ninewells Hospital
2015
University of Rochester Medical Center
2011-2013
University of Rochester
2012
Strong Memorial Hospital
2011
Global medium-range weather forecasting is critical to decision-making across many social and economic domains. Traditional numerical prediction uses increased compute resources improve forecast accuracy but does not directly use historical data the underlying model. Here, we introduce GraphCast, a machine learning-based method trained from reanalysis data. It predicts hundreds of variables for next 10 days at 0.25° resolution globally in under 1 minute. GraphCast significantly outperforms...
To evaluate single-shot fast spin-echo (SE) magnetic resonance (MR) imaging for depiction of pancreatic cysts in a large number patients and to analyze cyst prevalence with respect patient age sex other clinical information.Single-shot SE images the pancreas were obtained 1,444 patients. The reviewed presence cysts, which classified as simple nonsimple types, diameters measured. kappa statistic, Fisher exact, McNemar Q, Pearson product moment correlation tests performed.Two hundred...
The objectives of this study were to develop and show the efficacy a breath-hold ultrafast three-dimensional (3D) spoiled gradient-echo (SPGR) gadolinium-enhanced MR angiographic technique for imaging aorta renal other visceral arteries abdomen; compare 3D SPGR with two-dimensional (2D) time-of-flight (TOF) non-breath-hold in same patients.We prospectively studied abdominal 68 times 63 consecutive patients 2D TOF angiography. Thirty-two had contrast angiography (n = 23) and/or surgery 24)...
To prospectively assess patient response (after 12 months) to magnetic resonance (MR) imaging-guided focused ultrasound surgery in treatment of uterine leiomyomas by using two protocols.This prospective clinical trial was approved institutional review boards and HIPAA compliant. After giving informed consent, patients with symptomatic were consecutively enrolled treated at one five U.S. centers an original or a modified protocol. Outcomes assessed the symptom severity score (SSS) obtained...
PURPOSE: To determine whether a modified caudate–right lobe ratio (C/RL) with use of the right portal vein to set lateral boundary (C/RL-r) is more accurate for diagnosing cirrhosis and evaluating its clinical severity than previously described C/RL main (C/RL-m). MATERIALS AND METHODS: Two hundred thirty-six patients (121 pathologically proved 115 without history chronic hepatic diseases) underwent magnetic resonance (MR) imaging. independent observers measured C/RL-r compared it C/RL-m....
This study aims to define the epidemiology of trauma presenting a single centre providing all orthopaedic care for population ∼ 900,000 over first 40 days COVID-19 pandemic compared that same period one year earlier. The secondary aim was compare this with mobility data obtained from Google.A cross-sectional consecutive adult (> 13 years) patients musculoskeletal referred as either in-patients or out-patients 40-day beginning on 5 March 2020, date reported UK death, performed. time...
Abstract Building a large-scale quantum computer requires effective strategies to correct errors that inevitably arise in physical systems 1 . Quantum error-correction codes 2 present way reach this goal by encoding logical information redundantly into many qubits. A key challenge implementing such is accurately decoding noisy syndrome extracted from redundancy checks obtain the encoded information. Here we develop recurrent, transformer-based neural network learns decode surface code,...
In the first phase of this study, seven healthy subjects underwent examination with two-dimensional time-of-flight (TOF) magnetic resonance (MR) angiography to develop a protocol for evaluation peripheral arterial vasculature from infrarenal aorta foot. second phase, 73 patients symptomatic vascular disease both conventional contrast material-enhanced arteriography and TOF MR evaluate clinical usefulness angiography. Postinterventional intraoperative or direct surgical exploration was...
To establish age-based standards for renal cysts depicted at magnetic resonance (MR) imaging and to compare these with existing ultrasonography (US).Three radiologists reviewed subsecond T2-weighted single-shot fast spin-echo kidney MR findings in 528 patients (248 men, 280 women) selected from consecutive abdominal studies without regard clinical indication. Age, sex, number diameter of were noted. Results analyzed nonparametric tests compared published US results.Men (mean, 2.0; 95% CI:...
To evaluate the magnetic resonance (MR) venographic appearance of ovarian veins in a healthy population, correlated with surgical findings. Our data can be used as basis for comparison to patients suspected pelvic congestion syndrome (PCS).We retrospectively reviewed exams 22 women who had MR angiography potential renal donation evaluation (age range, 19.3-60.5 years; mean, 38 years). We evaluated diameter on dynamic multiphasic postcontrast coronal images, phase contrast these veins,...
Abstract Purpose To assess whether measuring the pattern of pancreatic enhancement on gadolinium chelate dynamic magnetic resonance imaging (MRI) is helpful for diagnosis suspected early or mild chronic pancreatitis. Materials and Methods In this retrospective study, 24 patients with pancreatitis, classified by criteria equivocal pancreatitis (ultrasound, computed tomography [CT] ERCP) grading, had MRI that included unenhanced, arterial dominant, venous, late venous phases contrast...
Abstract Purpose To determine the diagnostic performance of functional magnetic resonance cholangiography (fMRC) for evaluation anatomic and biliary disorders. Materials Methods At 1.5 T, 39 MR examinations with conventional MRC mangafodipir trisodium‐enhanced fMRC were retrospectively reviewed by three observers who recorded (duct dilation, stricture, filling defects) (cholecystitis, obstruction) abnormalities in modes: alone, images together (combined‐MRC). Performance was determined...
Although knee osteoarthritis (OA) is diagnosed and monitored radiologically, actual full-thickness cartilage loss (FTCL) has rarely been correlated with radiological classification. This study aims to analyze which classification system correlates best FTCL assess their reliability.A prospective of 300 consecutive patients undergoing unilateral total arthroplasty (TKA) for OA (mean age 69 years (44 91; standard deviation (SD) 9.5), 178 (59%) female). Two blinded examiners independently...
To prospectively evaluate three magnetic resonance (MR) imaging techniques for detection of pulmonary embolism.Eighteen patients in whom the presence acute or chronic emboli was suspected underwent examination with following pulse sequences: cardiac-gated spin echo, cine spatial modulation magnetization, and two-dimensional time-of-flight breath-hold (PBH) MR angiography. Three radiologists independently blindly reviewed each case graded a total 518 arterial segments sequence continuous...
A section-selective three-dimensional phosphorus-31 chemical shift imaging (CSI) experiment was evaluated as the spatial localization method for spectroscopy in an integrated clinical magnetic resonance (MR) and examination. The results of a CSI can be displayed either spectra related to specific voxels or "metabolite maps," which relative concentration given metabolite is overlay MR image. This applied study soft-tissue mass meningioma. total time each case 17 minutes with voxel size 27 cm3...
This study aims to determine the proportion of patients with end-stage knee osteoarthritis (OA) possibly suitable for partial (PKA) or combined arthroplasty (CPKA) according patterns full-thickness cartilage loss and anterior cruciate ligament (ACL) status.A cross-sectional analysis 300 consecutive (mean age 69 years (SD 9.5, 44 91), mean body mass index (BMI) 30.6 5.5, 20 53), 178 female (59.3%)) undergoing total (TKA) Kellgren-Lawrence grade ≥ 3 OA was conducted. The point maximal tibial...
Quantum error correction provides a path to reach practical quantum computing by combining multiple physical qubits into logical qubit, where the rate is suppressed exponentially as more are added. However, this exponential suppression only occurs if below critical threshold. In work, we present two surface code memories operating threshold: distance-7 and distance-5 integrated with real-time decoder. The of our larger memory factor $\Lambda$ = 2.14 $\pm$ 0.02 when increasing distance two,...
Magnetic resonance angiography (MRA) is a noninvasive vascular imaging technique that more sensitive than contrast arteriography (CA) for the detection of patent distal runoff vessels. This has facilitated performance MRA-directed bypass procedures patients who were believed not to be candidates because absence suitable target vessel on preoperative CA. The fate bypasses these angiographically occult vessels unknown, however, and it been proposed with may have aggressive occlusive disease,...