A5014122714- Calcium signaling and nucleotide metabolism
- Venomous Animal Envenomation and Studies
- Chromatography in Natural Products
- Protein purification and stability
- Drug Solubulity and Delivery Systems
- Crystallization and Solubility Studies
- Hippo pathway signaling and YAP/TAZ
- Plant-based Medicinal Research
- Toxin Mechanisms and Immunotoxins
- Pharmacological Effects of Natural Compounds
- Cell Adhesion Molecules Research
Centre National de la Recherche Scientifique
2017-2023
Université de Toulouse
2023
IMT Mines Albi
2023
Aix-Marseille Université
2017-2020
Institut de Chimie Radicalaire
2018-2020
In the soft treatment of cancer tumours, consequent downregulation malignant tissue angiogenesis constitutes an efficient way to stifle tumour development and metastasis spreading. As requires integrin–promoting endothelial cell adhesion, migration, vessel tube formation, integrins represent potential targets new therapeutic anti–angiogenic agents. Our work is a contribution research such disintegrins in animal venoms. We report isolation one peptide, named Dabmaurin–1, from hemotoxic venom...
The objective of this study was to improve the solubility and inhibit crystallisation during gastric-to-intestinal transfer Erlotinib (ERL), a small molecule kinase inhibitor (smKI) compound class, which is classified as class II drug in Biopharmaceutical Classification System (BCS). A screening approach combining different parameters (solubility aqueous media, inhibitory effect from supersaturated solutions) applied selected polymers for development solid amorphous dispersions ERL. ERL...