A5085459695- Ecology and Vegetation Dynamics Studies
- Botany, Ecology, and Taxonomy Studies
- Rangeland and Wildlife Management
- Plant biochemistry and biosynthesis
- Biological Control of Invasive Species
- Species Distribution and Climate Change
- Plant Diversity and Evolution
- Phenothiazines and Benzothiazines Synthesis and Activities
- Plant and animal studies
- Wildlife Ecology and Conservation
- Pasture and Agricultural Systems
- Invertebrate Taxonomy and Ecology
- Microbial Natural Products and Biosynthesis
- Synthesis and Biological Evaluation
- Pacific and Southeast Asian Studies
- Fire effects on ecosystems
- Environmental Conservation and Management
- RNA Research and Splicing
- Quinazolinone synthesis and applications
- Chemical Synthesis and Analysis
- Drilling and Well Engineering
- Synthetic Organic Chemistry Methods
- Microbial Metabolic Engineering and Bioproduction
- Protein purification and stability
- Algal biology and biofuel production
University of Newcastle Australia
2014-2024
Boehringer Ingelheim (United States)
2023
University of Utah
2022
GlaxoSmithKline (United Kingdom)
2017-2018
Timescape Surveys
2018
Royal Botanic Gardens, Kew
2015-2017
University of Kentucky
2010-2016
Royal Botanic Garden Sydney
2015
Royal Botanic Gardens Victoria
2015
Plant (United States)
2010
Marchantia polymorpha is a basal terrestrial land plant, which like most liverworts accumulates structurally diverse terpenes believed to serve in deterring disease and herbivory. Previous studies have suggested that the mevalonate methylerythritol phosphate pathways, present evolutionarily diverged plants, are also operative liverworts. However, genes enzymes responsible for chemical diversity of yet be described. In this study, we resorted HMMER search tool identify 17 putative terpene...
Botryococcus braunii race B is a colony-forming, green algae that accumulates triterpene oils in excess of 30% its dry weight. The composition the dominated by dimethylated to tetramethylated forms botryococcene and squalene. Although unusual mechanisms for biosynthesis squalene were recently described, enzyme(s) responsible decorating these scaffolds with methyl substituents unknown. A transcriptome B. was screened computationally assuming methyltransferases (TMTs) might resemble S-adenosyl...
The polyadenylation of RNA is a near-universal feature metabolism in eukaryotes. This process has been studied the model alga Chlamydomonas reinhardtii using low-throughput (gene-by-gene) and high-throughput (transcriptome sequencing) approaches that recovered poly(A)-containing sequence tags which revealed interesting features this critical Chlamydomonas. In study, so-called Poly(A) Tag Sequencing (PAT-Seq) approach. Specifically, PAT-Seq was used to study poly(A) site choice cultures grown...
Context The endangered ephemeral herb Monotaxis macrophylla (Euphorbiaceae) has limited (~211) records throughout its known range in eastern Australia. In New South Wales (NSW), the 127 occurrences are spread over more than half of state, and for regulatory purposes this led to 262 Plant Community Types (PCTs) being predicted as suitable habitat species BioNet Threatened Biodiversity Data Collection (TBDC). Under Assessment Method currently use NSW, is be specifically addressed any...
Iminophosphoranes of the type X(3)P=NR (X = Cl, pyrrolyl; R alkyl, aryl) catalytically metathesize C=N bonds carbodiimides via an addition/elimination mechanism that, despite lack d orbital participation in P-N bonding, conserves key features metal-catalyzed olefin metathesis. Diazaphosphetidine intermediates, produced by formal [2 + 2] addition to P=N bond, have been isolated and characterized. All phosphorus-containing species complex catalytic reaction mixtures identified their origins...
Squalene and botryococcene are branched-chain, triterpene compounds that arise from the head-to-head condensation of two molecules farnesyl diphosphate to yield 1′–1 1′–3 linkages, respectively. The enzymes catalyze their formation have attracted considerable interest medical field as potential drug targets renewable energy sector for metabolic engineering efforts. Recently, responsible squalene biosynthesis in green alga Botryococcus braunii race B were characterized. To better understand...
We report the identification of tnd biosynthetic cluster from marine-derived fungus Aspergillus flavipes and in vivo characterization a cryptic type I diterpene synthase. The heterologous expression bifunctional terpene synthase led to discovery backbone, talarodiene, harboring benzo[a]cyclopenta[d]cyclooctane tricyclic fused ring system. conversion geranylgeranyl diphosphate talarodiene was investigated using 13C-labeling studies, stable isotope tracer experiments showed biotransformation...
A solution-phase synthesis and characterization of covalent DNA-dendron conjugates is presented. Thiol-terminated 12-base oligonucleotides were added to second- third-generation triazine-based dendrons via thiol/disulfide exchange chemistry. Single-stranded DNA successfully attached at the core, periphery, both. Proof structure for these architectures derived primarily from mass spectrometry polyacrylamide gel electrophoresis complemented by labeling analysis using Ellman's reagent...
MINT‐7712550: AtCstF77 (uniprotkb:Q8LKG5) binds (MI:0407) to AtCPSF30 (uniprotkb:A9LNK9) by pull down (MI:0096)
Translocation of plants is used globally as a conservation action to bolster existing or establish new populations threatened species and usually communicated in academic publications case studies. also mitigate offset impacts urbanization development but less often publicly published. Irrespective the motivation, mitigation, on ground actions are driven by overriding global goals, applied local national legislation. This paper deconstructs legislative framework which guides translocation...
Re‐introduction of threatened plants is an emerging tool in biodiversity conservation; however, the efficacy and success translocations vary. This study documents translocation two terrestrial orchid species ( Diuris tricolor , Prasophyllum petilum ) over 8 years within coal mining areas Hunter Valley NSW, Australia. In largest scale known (and only one translocating into mine rehabilitation), six events have progressively re‐located 3,030 mature orchids (1,206 D. 1,824 P. offsets...
Iminophosphorane Cl3PNAr (Ar = 2-fluorophenyl) is an active carbodiimide metathesis catalyst and the cycloaddition product, a 1,3-diaza-2-phosphetidine, intermediate in reaction.
The objective of this study was to improve the solubility and inhibit crystallisation during gastric-to-intestinal transfer Erlotinib (ERL), a small molecule kinase inhibitor (smKI) compound class, which is classified as class II drug in Biopharmaceutical Classification System (BCS). A screening approach combining different parameters (solubility aqueous media, inhibitory effect from supersaturated solutions) applied selected polymers for development solid amorphous dispersions ERL. ERL...
Summary Translocation of threatened terrestrial orchids is increasingly seen as a viable ameliorative conservation option when habitat destroyed or modified through changing land use. Most orchid translocations reported in the literature detail nursery‐raised seedlings planted into intact and suitable habitat, few involve translocation entire plants their mycorrhizal fungal associates. As part larger study, soil cores containing 46 individuals Painted Diuris ( tricolor ) were translocated...
Abstract Barite Sag is a reoccurring problem with many oil-based drilling fluids. Attempts to correlate sag tendencies various rheological properties commonly used benchmark fluids have had limited success in prevention and anticipation of problems the field. Herein presented new testing apparatus for dynamic static settling rate (sag) measurements, which has been proven provide better understanding phenomena as well means characterize fluid performance. This greatly expands precision...
A new subspecies of Leionema lamprophyllum, formerly included in L. lamprophyllum subsp. obovatum F.M.Anderson, is here described as new. Currently known from fewer than 50 individuals, the highly restricted and warrants a conservation risk code at least Endangered. An illustration taxon, notes on its distribution habitat, key to all four are also provided.
It was my pleasure to attend the conference and meet hear from a range of authoritative, passionate, distinguished plant conservationists.With over 50 presentations in three concurrent sessions, along with keynote address four plenary lectures, three-day packed full information ideas.
Upland wetlands, commonly known as hanging swamps, are scattered throughout the Somersby Plateau and depend on groundwater to maintain their floristic diversity.Although such communities limited in areal extent, they provide islands of distinct vegetation assemblages somewhat different surrounding community.While not currently protected legally, these swamps unique ecological communities, providing potential habitat for threatened species regent honeyeater, redcrowned toadlet, Adams emerald...