A5018783492- Heart Failure Treatment and Management
- Cardiac pacing and defibrillation studies
- Cardiovascular Function and Risk Factors
- Pharmaceutical Practices and Patient Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Gene expression and cancer classification
- HIV, Drug Use, Sexual Risk
- Eicosanoids and Hypertension Pharmacology
- Pulmonary Hypertension Research and Treatments
- Neuroscience and Neuropharmacology Research
- Cardiac Arrhythmias and Treatments
- Bladder and Urothelial Cancer Treatments
- Obesity, Physical Activity, Diet
- Renal cell carcinoma treatment
- Substance Abuse Treatment and Outcomes
- COVID-19 Clinical Research Studies
- Machine Learning in Healthcare
- Hernia repair and management
- Epilepsy research and treatment
- Child Nutrition and Water Access
- Atrial Fibrillation Management and Outcomes
- Artificial Intelligence in Healthcare
- Cardiac, Anesthesia and Surgical Outcomes
- Infrared Thermography in Medicine
- Long-Term Effects of COVID-19
University of California, Los Angeles
2019-2025
Cold Spring Harbor Laboratory
2022
Cedars-Sinai Smidt Heart Institute
2022
Cedars-Sinai Medical Center
2022
Yale University
2015-2018
Importance Some individuals who were infected by the SARS-CoV-2 Omicron variant may have been completely unaware of their infectious status while virus was actively transmissible. Objective To examine awareness among during recent surge in a diverse and populous urban region Los Angeles County. Design, Setting, Participants This cohort study analyzed records adult employees patients an academic medical center enrolled longitudinal COVID-19 serological County, California. These participants...
Background: Pediatric overweight and obesity has become a major public health problem in China. The goal of this study is to understand preschool children Changsha City the context their sleep physical activity. These results offer feasible proposals reduce levels among children. Methods: A total 112 preschoolers aged three six years old were investigated using multiple stage stratified cluster sampling simple random sampling. Questionnaires used collect general information about families....
Significance Despite extraordinary advances in the treatment of HIV, global pandemic has yet to be reversed. We developed a mathematical model for 127 countries evaluate Joint United Nations Program on HIV/AIDS (UNAIDS) targets expanding diagnosis and infected, partially efficacious HIV vaccination. Under current levels treatment, we estimated 49 million new cases globally from 2015 2035. Achieving ambitious UNAIDS target is predicted avert 25 these infections, with an additional 6.3 averted...
Importance Guideline-directed medical therapy (GDMT) remains underutilized on a global level, with significant disparities in access to treatment worldwide. The potential benefits of quadruple patients heart failure reduced ejection fraction (HFrEF) have not yet been estimated. Objective To assess the projected population-level benefit optimal GDMT use globally among HFrEF. Design, Setting, and Participants Estimates for HFrEF prevalence, contraindications GDMT, rates, number needed treat...
Abstract Background Individuals with post-acute sequelae of COVID (PASC) may have a persistence in immune activation that differentiates them from individuals who recovered without clinical sequelae. To investigate how humoral vary this regard, we compared patterns vaccine-provoked serological response patients PASC to prior PASC. Methods We prospectively studied 245 adults clinically diagnosed and 86 successfully COVID. All participants had measures immunity SARS-CoV-2 assayed before or...
Improving the identification of people who inject drugs (PWID) in electronic medical records can improve clinical decision making, risk assessment and mitigation, health service research. Identification PWID currently consists heterogeneous, nonspecific International Classification Diseases (ICD) codes as proxies. Natural language processing (NLP) machine learning (ML) methods may have better diagnostic metrics than ICD for identifying PWID. We manually reviewed 1000 patients diagnosed with...
Introduction: Early childhood obesity in China has become a pressing public health concern. A substantial barrier to healthy weight management is poor parental recognition of child overweight. This study examined the relationship between caregiver perceptions and dietary practices. Methods: total 364 children 2 6 years old from six urban preschools Changsha (China) were included cross-sectional study. Information on household demographics, behaviors, attitudes was collected through...
Ventricular ablation may be clinically indicated for patients with recurrent ventricular tachycardia (VT) and has been shown to decrease risk of recurrence overall morbidity. However, the existence disparities among receiving not well characterized. In this study, we examined hospitalized VT determine whether exist those ablations. We used National Inpatient Sample assess a primary diagnosis in 2019 who did receive catheter Multiple logistic regression was calculate factors based on age,...
Home-time is an emerging, patient-centered outcome that represents the amount of time a patient spends alive and outside health care facility settings, comprising hospitals, skilled nursing facilities, acute rehabilitation centers. Studies evaluating home-time in context heart failure are limited, impact quality improvement interventions on has not been studied.
<h3>Importance</h3> Overdose is one of the leading causes death in US; however, surveillance data lag considerably from medical examiner determination to reporting national reports. <h3>Objective</h3> To automate classification deaths related substances using natural language processing (NLP) and machine learning (ML). <h3>Design, Setting, Participants</h3> Diagnostic study comparing different algorithms identify overdose 10 health jurisdictions US January 1, 2020, December 31, 2020....
The caregivers of left-behind children (CLBC) in China's poor, rural areas are mostly elderly and women. Their health status access to services have not been previously characterized. This study aims explore the CLBC terms their service utilization provide a scientific basis for guiding effective implementation policy Hunan.Random cluster sampling was used survey two counties. Face-to-face interviews questionnaires were collect data, including socioeconomic utilization. two-week prevalence...
IntroductionWe conducted a population-based observational study of all medical examiner cases in Los Angeles County from January 2012 through June 2021 which methamphetamine was listed as cause or contributing factor to death (n = 6125). We aimed characterize demographics, comorbidities, and co-involved substances methamphetamine-related deaths longitudinally County, California.MethodsWe used detailed record data manually classify fatalities by involvement each organ system, opioids,...
The essential branched-chain amino acids (BCAAs) leucine, isoleucine, and valine have recently emerged as a potential novel treatment for medically refractory epilepsy. Blood-derived BCAAs can readily enter the brain, where they contribute to glutamate biosynthesis may either suppress or trigger acute seizures. However, effects of on chronic (ie, spontaneous recurrent) seizures epilepsy-associated neuron loss are incompletely understood.Sixteen rats with mesial temporal lobe epilepsy were...