A5055736275- COVID-19 epidemiological studies
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Viral Infections and Outbreaks Research
- HIV/AIDS Research and Interventions
- COVID-19 and healthcare impacts
- Vaccine Coverage and Hesitancy
- Trypanosoma species research and implications
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- HIV, Drug Use, Sexual Risk
- Disaster Response and Management
- Health disparities and outcomes
- Bone fractures and treatments
- Global Health Care Issues
- Healthcare Policy and Management
- Migration and Labor Dynamics
- COVID-19 Clinical Research Studies
- Parasitic Diseases Research and Treatment
- HIV Research and Treatment
- Respiratory viral infections research
- Parasites and Host Interactions
- Mental Health via Writing
- Social Media in Health Education
- Digital Mental Health Interventions
Yale University
2016-2025
International Biometric Society
2024
Indian Institute of Technology Mandi
2024
University Physicians
2023
University of South Florida
2023
Institute for Disease Modeling
2022
Era's Lucknow Medical College and Hospital
2016-2021
NYU Langone Health
2021
University of Cambridge
2021
University of Hong Kong
2021
The novel coronavirus outbreak (COVID-19) in mainland China has rapidly spread across the globe. Within 2 mo since was first reported on December 31, 2019, a total of 566 Severe Acute Respiratory Syndrome (SARS CoV-2) cases have been confirmed 26 other countries. Travel restrictions and border control measures enforced countries to limit outbreak. We estimate impact these investigate role airport travel network global COVID-19 Our results show that daily risk exporting at least single SARS...
In the wake of community coronavirus disease 2019 (COVID-19) transmission in United States, there is a growing public health concern regarding adequacy resources to treat infected cases. Hospital beds, intensive care units (ICUs), and ventilators are vital for treatment patients with severe illness. To project timing outbreak peak number ICU beds required at peak, we simulated COVID-19 parameterized US population demographics. scenario analyses, varied delay from symptom onset...
Since the emergence of coronavirus disease 2019 (COVID-19), unprecedented movement restrictions and social distancing measures have been implemented worldwide. The socioeconomic repercussions fueled calls to lift these measures. In absence population-wide restrictions, isolation infected individuals is key curtailing transmission. However, effectiveness symptom-based in preventing a resurgence depends on extent presymptomatic asymptomatic We evaluate contribution transmission based recent...
The ongoing Ebola outbreak poses an alarming risk to the countries of West Africa and beyond. To assess effectiveness containment strategies, we developed a stochastic model transmission between within general community, hospitals, funerals, calibrated incidence data from Liberia. We find that combined approach case isolation, contact-tracing with quarantine, sanitary funeral practices must be implemented utmost urgency in order reverse growth outbreak. As 19 September, under status quo, our...
Abstract For COVID-19, it is vital to understand if quarantines shorter than 14 days can be equally effective with judiciously deployed testing. Here, we develop a mathematical model that quantifies the probability of post-quarantine transmission incorporating testing into travel quarantine, quarantine traced contacts an unknown time infection, and cases known exposure. We find on exit (or entry exit) reduce duration 14-day by 50%, while shortens at most one day. In real-world test our...
SummaryBackgroundTo mitigate the COVID-19 pandemic, countries worldwide have enacted unprecedented movement restrictions, physical distancing measures, and face mask requirements. Until safe efficacious vaccines or antiviral drugs become widely available, viral testing remains primary mitigation measure for rapid identification isolation of infected individuals. We aimed to assess economic trade-offs expanding accelerating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) across...
Significance There is limited understanding of what ramifications conflict events have on disease transmission and control in regions plagued by civil unrest violence. Furthermore, the multifaceted nature during an epidemic yet to be characterized. Using data, ethnographic appraisal, a mathematical model, we provide descriptive timeline ongoing Ebola outbreak Democratic Republic Congo. We quantified preceding event its subsequent impact activities demonstrate how are contributing persistence...
The fragmented and inefficient healthcare system in the United States leads to many preventable deaths unnecessary costs every year. During a pandemic, lives saved economic benefits of single-payer universal relative status quo would be even greater. For Americans who are uninsured underinsured, financial barriers COVID-19 care delayed diagnosis exacerbated transmission. Concurrently, beyond accrued from background rate uninsurance. Universal alleviate mortality caused by confluence these...
However, the population-level effectiveness of vaccination campaign in US, terms association with reduced infections, hospitalizations, and deaths, is not as well documented, we evaluated this using a simulation model. Methods This decision analytic model adheres to Consolidated Health Economic Evaluation ReportingStandards (CHEERS) reporting guideline.The institutional review study was waived by York University for use publicly available, deidentified data COVID-19 vaccination.Informed...
Quantitative analysis and mathematical models are useful tools in informing strategies to control or eliminate disease. Currently, there is an urgent need develop these inform policy achieve the 2020 goals for neglected tropical diseases (NTDs). In this paper we give overview of a collection novel model-based analyses which aim address key questions on dynamics transmission nine NTDs: Chagas disease, visceral leishmaniasis, human African trypanosomiasis, leprosy, soil-transmitted helminths,...
Over 20,000 rabies deaths occur annually in India, representing one-third of global human rabies. The Indian state Tamil Nadu has pioneered a “One Health” committee to address the challenge dogs and humans. Currently, control involves postexposure vaccination humans after dog bites, whereas potential supplemental approaches include canine sterilization. We developed data-driven transmission model fit autopsy data surveillance from Nadu. Integrating local estimates for demography costs, we...
Significance Despite extraordinary advances in the treatment of HIV, global pandemic has yet to be reversed. We developed a mathematical model for 127 countries evaluate Joint United Nations Program on HIV/AIDS (UNAIDS) targets expanding diagnosis and infected, partially efficacious HIV vaccination. Under current levels treatment, we estimated 49 million new cases globally from 2015 2035. Achieving ambitious UNAIDS target is predicted avert 25 these infections, with an additional 6.3 averted...
Following the April 2018 reemergence of Ebola in a rural region Democratic Republic Congo (DRC), virus spread to an urban center by early May. Within 2 wk first case confirmation, vaccination campaign was initiated which 3,017 doses were administered contacts cases and frontline healthcare workers. To evaluate spatial dynamics transmission quantify impact vaccination, we developed geographically explicit model that incorporates high-resolution data on poverty population density. We found...
Given global Coronavirus Disease 2019 (COVID-19) vaccine shortages and inequity of distributions, fractionation doses might be an effective strategy for reducing public health economic burden, notwithstanding the emergence new variants concern. In this study, we developed a multi-scale model incorporating population-level transmission individual-level vaccination to estimate costs hospitalization benefits COVID-19 deaths due dose-fractionation strategies in India. We used large-scale survey...
To better understand factors influencing life expectancy, this paper examines how the availability of publicly funded health care in a country and multiple social determinants impact longevity life.In descriptive statistical analysis, data regarding care, were obtained for 196 countries 4 territories. Social included 10 indicators detailing country-level information to represent 5 key categories: economic stability, education, & neighbourhood built environment, community context. Analyses...
Obesity is a major public health crisis in the United States (US) affecting 42% of population, exacerbating spectrum other diseases and contributing significantly to morbidity mortality overall. Recent advances pharmaceutical interventions, particularly glucagon-like peptide-1 (GLP-1) receptor agonists (e.g., semaglutide, liraglutide) dual gastric inhibitory polypeptide GLP-1 tirzepatide), have shown remarkable efficacy weight-loss. However, limited access these medications due high costs...
Black populations in the United States are being disproportionately affected by COVID-19 pandemic, but increased mortality burden after accounting for health and other demographic characteristics is not well understood. We examined of individuals who died from Michigan race stratified their age, sex comorbidity prevalence to illustrate understand this disparity risk.
Abstract Importance Randomized clinical trials have shown that the COVID-19 vaccines currently approved in US are highly efficacious. However, more evidence is needed to understand population-level impact of vaccination rollout face changing landscape pandemic US, including variants with higher transmissibility and immune escape. Objective To quantify campaign averting cases, hospitalizations deaths from December 12, 2020 June 28, 2021. Design Age-stratified agent-based model which included...
The authors sought to study the risk factors associated with severe outcomes in hospitalized coronavirus disease 2019 (COVID-19) patients cancer.The queried New York University Langone Medical Center's records for who were polymerase chain reaction-positive acute respiratory syndrome 2 (SARS CoV-2) and performed chart reviews on cancer diagnoses identify active a history of cancer. Descriptive statistics calculated multivariable logistic regression was used determine associations between...
Numerous countries have imposed strict travel restrictions during the COVID-19 pandemic, contributing to a large socioeconomic burden. The long quarantines that been applied contacts of cases may be excessive for policy.We developed an approach evaluate imminent countrywide infections after 0-14-day quarantine and testing. We identified minimum duration such infection rate within destination country did not increase compared ban, defining this as "sufficient."We present generalised...