Rajiv Saran

ORCID: 0000-0001-7317-8756
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About
Contact & Profiles
Research Areas
  • Dialysis and Renal Disease Management
  • Chronic Kidney Disease and Diabetes
  • Central Venous Catheters and Hemodialysis
  • Blood Pressure and Hypertension Studies
  • Healthcare Policy and Management
  • Acute Kidney Injury Research
  • Vascular Procedures and Complications
  • Renal and Vascular Pathologies
  • Health Systems, Economic Evaluations, Quality of Life
  • Research on Leishmaniasis Studies
  • Sodium Intake and Health
  • Potassium and Related Disorders
  • Renal Diseases and Glomerulopathies
  • Renal Transplantation Outcomes and Treatments
  • Renal function and acid-base balance
  • Nutritional Studies and Diet
  • Diabetes Treatment and Management
  • Healthcare Systems and Reforms
  • Climate Change and Health Impacts
  • Global Public Health Policies and Epidemiology
  • Muscle and Compartmental Disorders
  • Health disparities and outcomes
  • Statistical Methods and Inference
  • Healthcare cost, quality, practices
  • Food Security and Health in Diverse Populations

University of Michigan
2016-2025

Michigan United
2016-2025

Central University of Haryana
2025

Michigan Medicine
2007-2024

The Centers
2020-2021

Centers for Disease Control and Prevention
2016-2020

Arbor Research Collaborative for Health
2004-2019

All India Institute of Medical Sciences
2019

Diabetes Australia
2018

National Center for Health Statistics
2016

Trends in the prevalence of chronic kidney disease (CKD) are important for health care policy and planning.To update trends CKD prevalence.Repeated cross-sectional study.NHANES (National Health Nutrition Examination Survey) 1988 to 1994 every 2 years from 1999 2012.Adults aged 20 or older.Chronic (stages 3 4) was defined as an estimated glomerular filtration rate (eGFR) 15 59 mL/min/1.73 m2, with Chronic Kidney Disease Epidemiology Collaboration equation calibrated serum creatinine...

10.7326/m16-0273 article EN Annals of Internal Medicine 2016-08-01

Use of peripherally inserted central catheters (PICCs) has grown substantially in recent years. Increasing use led to the realization that PICCs are associated with important complications, including thrombosis and infection. Moreover, some may not be placed for clinically valid reasons. Defining appropriate indications insertion, maintenance, care is thus patient safety. An international panel was convened applied RAND/UCLA Appropriateness Method develop criteria PICCs. After systematic...

10.7326/m15-0744 article EN cc-by Annals of Internal Medicine 2015-09-15

Background: Patients with end-stage kidney disease (ESKD) on dialysis were excluded from clinical trials of direct oral anticoagulants for atrial fibrillation (AF). Recent data have raised concerns regarding the safety dabigatran and rivaroxaban, but apixaban has not been evaluated despite current labeling supporting its use in this population. The goal study was to determine patterns associated outcomes dialysis-dependent patients ESKD AF. Methods: We performed a retrospective cohort...

10.1161/circulationaha.118.035418 article EN Circulation 2018-06-28

Prevalence of chronic kidney disease (CKD) in people with diagnosed diabetes is known to be high, but little about the prevalence CKD those undiagnosed or prediabetes. We aimed estimate and compare community among diabetes, prediabetes, no diabetes.The 1999 through 2006 National Health Nutrition Examination Survey a representative survey civilian, noninstitutionalized US population. Participants who were aged > =20 years; responded questionnaire; had fasting plasma glucose (FPG), serum...

10.2215/cjn.07891109 article EN Clinical Journal of the American Society of Nephrology 2010-03-26

Background. Levels of physical exercise among haemodialysis patients are low. Increased activity in this population has been associated with improved health-related quality life (HRQoL) and survival. However, results previous studies may not be applicable to the as a whole. The present study provides first description international patterns frequency its association programmes clinical outcomes participants Dialysis Outcomes Practice Patterns Study (DOPPS).

10.1093/ndt/gfq138 article EN Nephrology Dialysis Transplantation 2010-04-13

The impact of recent guidelines for early detection and prevention chronic kidney disease (CKD) on patient awareness factors that might be associated with have not been well described.Awareness rates were assessed in 2992 adults (age, > or =20 years) CKD stages 1 to 4 from a nationally representative, cross-sectional survey (National Health Nutrition Examination Survey 1999-2004). Awareness was defined by an answer yes "Have you ever told weak failing kidneys?" Potential predictors included...

10.1001/archinte.168.20.2268 article EN Archives of Internal Medicine 2008-11-10

Poor sleep quality (SQ) affects many haemodialysis (HD) patients and could potentially predict their morbidity, mortality, of life (QOL) patterns medication use.Data on SQ were collected from 11,351 in 308 dialysis units seven countries the Dialysis Outcomes Practice Patterns Study (DOPPS) between 1996 2001 through a patient self-reported scale, ranging 0 (worst) to 10 (best). A score <6 reflected poor SQ. Sleep disturbance was also assessed by daytime sleepiness, feeling drained nocturnal...

10.1093/ndt/gfm630 article EN Nephrology Dialysis Transplantation 2007-10-03

Background Population rates of obesity, hypertension, diabetes, age, and race can be used in simulation models to develop projections ESRD incidence prevalence. Such inform long-range planning for resources needs. Methods We an open compartmental model estimate the prevalence United States through 2030 on basis wide-ranging population obesity death rates. trends race, diabetes were data from Centers Disease Control Prevention’s National Health Nutrition Examination Survey US Census. Results...

10.1681/asn.2018050531 article EN Journal of the American Society of Nephrology 2018-12-17

India is the diabetes capital with home to 69.1 million people DM, second highest number of cases after China. Recent epidemiological evidence indicates a rising DM epidemic across all classes, both affluent and poor in India. This article reports on prevalence pre-diabetes North Indian state Punjab as part large household NCD Risk Factor Survey. A STEPS survey was done Punjab, multistage stratified sample 5127 individuals. All subjects were administered WHO questionnaire, anthropometric...

10.1186/s13098-017-0207-3 article EN cc-by Diabetology & Metabolic Syndrome 2017-01-23

Objective Oxidative stress and oxidized high‐density lipoprotein (HDL) are implicated as risk factors for cardiovascular disease (CVD) in systemic lupus erythematosus (SLE). Yet, how HDL is rendered dysfunctional SLE remains unclear. Neutrophil extracellular traps (NETs), the levels of which elevated lupus, possess oxidant‐generating enzymes, including myeloperoxidase (MPO), NADPH oxidase (NOX), nitric oxide synthase (NOS). We hypothesized that NETs mediate oxidation, impairing cholesterol...

10.1002/art.38703 article EN Arthritis & Rheumatology 2014-05-16

Small clinical trials have shown that a reduction in dietary acid load (DAL) improves kidney injury and slows function decline; however, the relationship between DAL risk of ESRD population-based cohort with CKD remains unexamined. We examined association DAL, quantified by net excretion (NAEes), progression to nationally representative sample adults United States. Among 1486 age≥20 years enrolled National Health Nutrition Examination Survey III, was determined 24-h recall questionnaire. The...

10.1681/asn.2014040332 article EN Journal of the American Society of Nephrology 2015-02-13

Background— Patients with end-stage renal disease are at high risk for cardiovascular morbidity and mortality. The aims of the present study were to describe prevalence peripheral arterial (PAD) its effects on prognosis health-related quality life (HRQOL) in an international cohort patients hemodialysis. Methods Results— Data from Dialysis Outcomes Practice Patterns Study (DOPPS), a prospective, international, observational hemodialysis (n=29 873), analyzed. Associations between baseline...

10.1161/circulationaha.105.607390 article EN Circulation 2006-10-24
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