A5013359601- Congenital Heart Disease Studies
- Cardiac Arrhythmias and Treatments
- Cardiovascular Issues in Pregnancy
- Systemic Lupus Erythematosus Research
- Cardiovascular Conditions and Treatments
- Cardiomyopathy and Myosin Studies
- Viral Infections and Immunology Research
- Congenital Diaphragmatic Hernia Studies
- Mechanical Circulatory Support Devices
- Immunodeficiency and Autoimmune Disorders
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Vascular anomalies and interventions
- Blood groups and transfusion
- Cardiac electrophysiology and arrhythmias
- Pregnancy and Medication Impact
- Birth, Development, and Health
- Cardiovascular and exercise physiology
- Acute Myocardial Infarction Research
- Ultrasound in Clinical Applications
- Hearing Loss and Rehabilitation
- Heparin-Induced Thrombocytopenia and Thrombosis
- Cardiac Structural Anomalies and Repair
- Hearing, Cochlea, Tinnitus, Genetics
- Ear Surgery and Otitis Media
University of Kentucky
2017-2023
Levine Children's Hospital
2023
Emory University
2012-2013
Meyer Children's Hospital
2013
University of Iowa Stead Family Children’s Hospital
2010
Objective This prospective study of pregnant patients, S urveillance To P revent AV B lock L ikely to O ccur Q uickly (STOP BLOQ), addresses the impact anti‐SSA/Ro titers and utility ambulatory monitoring in detection fetal second‐degree atrioventricular block (AVB). Methods Women with autoantibodies by commercial testing were stratified into high low anti–52‐kD and/or 60‐kD SSA/Ro applying at‐risk thresholds defined previous evaluation AVB pregnancies. The high‐titer group performed heart...
Background: The prevalence of hypertension is increasing particularly among obese children and adolescents. Obese adolescents with are likely to remain hypertensive as they reach adulthood linked an increased risk for cardiovascular disease. Twenty-four-hour ambulatory blood pressure monitoring (ABPM) has become one the most important tools in diagnosing circadian patterns may be disease-risk predictors. Methods: A retrospective chart review was conducted patients aged 6–21 years who...
<b><i>Background:</i></b> Late-preterm and early-term (LP-ET) infants, defined herein as 35&#8304;-37<sup>6</sup> weeks' gestation, often fail on 1st otoacoustic emissions (OAE) test. Hypothesis: LP-ET infants more than term (38&#8304;-42 gestation) the OAE <b><i>Aim</i></b>: To evaluate effect of gestational age <b><i>Methods:</i></b> We studied 1,572 vaginally-delivered (VD) ≥35 gestation...
Introduction:: The management of anti-Ro/SSA positive pregnancies is challenging because fetal atrioventricular (AV) block rare and echo seldom detects reversible injury. Hypothesis: We hypothesized that ambulatory heart rate/rhythm monitoring improves detection AV when compared with echo. Methods: Anti-Ro antibody subjects from 21 US centers at less than 20 weeks gestation were risk stratified into high low anti-Ro60 52 titers the New York University (NYU) core laboratory. Low titer was...
<h3>Introduction</h3> Fetal cardiac disease is strongly associated with maternal anti-SSA/Ro antibodies, but gaps in our knowledge include the influence of antibody specificity and titer, diagnosis, overall non-cardiac adverse pregnancy outcomes (APOs), optimal surveillance protocols, efficacy rapid treatment. <h3>Methods</h3> The multi-center <b>S</b>urveillance <b>T</b>reatment T<b>o P</b>revent AV <b>B</b>lock <b>L</b>ikely to <b>O</b>ccur <b>Q</b>uickly (STOP BLOQ) study recruited...
Data suggest that anti-inflammatory treatment of 2° AV block (AVB) in anti-Ro antibody pregnancies may prevent progression to 3° and avert the substantial morbidity mortality this disease. The transition from irregular rhythm AVB bradycardia can occur overnight, thus frequent fetal heart rate monitoring (FHRM) might be more successful than weekly echocardiograms (echoes) detect period. We reviewed medical records a multicentre, open label clinical trial referred by rheumatologists MFMs risk...
Introduction: Fetal complete AV block (CAVB), complicates 2% of anti-Ro antibody positive pregnancies and carries substantial perinatal morbidity mortality. Anti-inflammatory treatment 1° 2° (emergent) AVB may prevent progression to CAVB, yet the optimal surveillance strategy detect emergent CAVB is unknown. Methods: We examined participants in a multicenter, open label clinical trial risk stratified by antibodies into high (≥1000 IU) or low (<1000 titers. Low titer mothers were followed...