Mesut Şahin

ORCID: 0000-0001-7404-9083
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About
Contact & Profiles
Research Areas
  • Liver physiology and pathology
  • Glycosylation and Glycoproteins Research
  • Pancreatic function and diabetes
  • Galectins and Cancer Biology
  • Mesenchymal stem cell research
  • Bone Tumor Diagnosis and Treatments
  • Sarcoma Diagnosis and Treatment
  • Antimicrobial Peptides and Activities
  • Organ Transplantation Techniques and Outcomes
  • Tissue Engineering and Regenerative Medicine
  • Invertebrate Immune Response Mechanisms
  • Aquaculture disease management and microbiota
  • RNA Interference and Gene Delivery
  • Bee Products Chemical Analysis
  • Wnt/β-catenin signaling in development and cancer
  • Cancer Mechanisms and Therapy
  • Estrogen and related hormone effects
  • Neuroblastoma Research and Treatments
  • Acupuncture Treatment Research Studies
  • Biochemical and Structural Characterization
  • Non-Invasive Vital Sign Monitoring
  • Prion Diseases and Protein Misfolding
  • Toxin Mechanisms and Immunotoxins
  • Hippo pathway signaling and YAP/TAZ
  • RNA regulation and disease

State Hospital
2025

Atatürk University
2017-2020

Manisa Celal Bayar University
2007-2016

University of Minnesota
2008-2012

University of Minnesota Medical Center
2009

Widespread use of liver transplantation in the treatment hepatic diseases is restricted by limited availability donated organs. One potential solution to this problem would be isolation and propagation progenitor cells or stem cells. Here, we report on a novel cell population from unmanipulated (that is, no prior exposure chemicals injury) adult rat liver. Rat were cultured following protocol developed our laboratory generate unique called liver-derived (LDPCs). LDPCs analyzed...

10.1002/lt.21380 article EN Liver Transplantation 2008-02-27

This review article's objectives are to examine the application of bee products in Chronic Obstructive Pulmonary Disease (COPD) and show how useful they for raising standard healthcare, particularly nursing care services. COPD, a widespread chronic condition, is significant public health issue. A promising approach COPD patients has emerged form growing interest traditional, complementary, integrative medicine as well extensive these treatments healthcare services recent years. Apart from...

10.71255/maunsbd.1573452 article EN 2025-04-30

Chordomas are rare tumors of the spine and skull base that locally destructive resistant to chemotherapy radiation therapy, with a poor prognosis limited therapeutic options. Chordoma patients have long life expectancy high mortality from disease. Cancer stem cells, which known exist in chordomas, extensive proliferative self-renewal potential responsible for maintaining tumor heterogeneity along radiotherapy resistance. Leukemia inhibitory factor (LIF) has multiple functions cell biology,...

10.3727/096504017x14874349473815 article EN Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 2017-03-01

We recently reported the isolation and characterization of a novel population progenitor cells called liver-derived (LDPCs), which could differentiate into functional hepatocytes in vitro. However, our original studies resulted relatively low variable hepatic differentiation efficiency without validation vivo potential LDPCs. Here, we report an efficient robust LDPCs under well-defined culture conditions to mature hepatocytes. In addition morphological studies, performed...

10.1002/lt.22111 article EN Liver Transplantation 2010-06-01

10.3923/pjbs.2006.1852.1860 article EN Pakistan Journal of Biological Sciences 2006-05-01

Tunikamisin proteinlerdeki asparagin gruplarinin N-glikozilasyonunu inhibe etme yetenegi ve endoplazmik retikulum stresini arttirmasi nedeniyle hucre biyolojisi calismalarinda yogun olarak kullanilan bir antibiyotiktir. Bu calismada tunikamisinin embriyonik hayatin 17. gunu ile 1. 3. postnatal gunlere ait fare dalak dokularindaki etkileri, 1) glikozaminoglikan molekullerindeki degisiklikler, 2) apoptozis 3) laminin degisiklikler olmak uzere 3 yapisal fizyolojik parametre arastirilmistir....

10.9775/kvfd.2009.064-a article TR Kafkas Universitesi Veteriner Fakultesi Dergisi 2009-01-01
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