A5058865032- Prostate Cancer Treatment and Research
- Radiopharmaceutical Chemistry and Applications
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Colorectal Cancer Screening and Detection
- Neuroblastoma Research and Treatments
- Prostate Cancer Diagnosis and Treatment
- Hormonal and reproductive studies
- Lung Cancer Research Studies
- Peptidase Inhibition and Analysis
- Esophageal Cancer Research and Treatment
- Head and Neck Cancer Studies
- Cancer and Skin Lesions
- Ear and Head Tumors
- Cancer Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Adrenal and Paraganglionic Tumors
- Salivary Gland Tumors Diagnosis and Treatment
- Trauma Management and Diagnosis
- Medical Imaging and Pathology Studies
- Thyroid Cancer Diagnosis and Treatment
- Nonmelanoma Skin Cancer Studies
- Bone health and treatments
Peter MacCallum Cancer Centre
2017-2025
The University of Melbourne
2019-2025
Walter Reed National Military Medical Center
2021
St. Joseph Dental College
2014-2015
Gandhi Medical College
2015
Royal Brisbane and Women's Hospital
2006-2014
The University of Queensland
2012-2014
Queensland Police Service
2010-2013
Westmead Hospital
2013
GTx (United States)
2011-2012
[177Lu]Lu-prostate-specific membrane antigen (PSMA) therapy has a favorable toxicity profile in patients with metastatic castration-resistant prostate cancer (mCRPC). Therapy-related myeloid neoplasm (t-MN) been described after [177Lu]Lu-DOTATATE but not, to our knowledge, yet reported [177Lu]Lu-PSMA. This case series describes 5 mCRPC who developed t-MN [177Lu]Lu-PSMA at institution. Methods: In this single-center retrospective analysis, we reviewed all treated Patients biopsy-proven during...
Previously, we demonstrated that prostate-specific membrane antigen positron emission tomography (PSMA-PET) revealed distant metastases in 109/200 patients (39% nodes, 24% bone, and 6% visceral organ) with nonmetastatic castration-resistant prostate cancer (nmCRPC) high-risk features (International Society of Urological Pathology score ≥4 and/or doubling time ≤10 mo) without by conventional imaging. However, the impact disease extent determined PSMA-PET on patient outcomes is unknown. We...
Assessment of serum Zinc in LBW (Low Birth Weight) and appropriate for gestational age (AGA) neonates relation to their maternal zinc level.A prospective study was conducted a tertiary care teaching hospital central India between August 2011 July 2012. Serum samples were collected from the eligible (preterm & term IUGR) AGA healthy mothers level estimation. measured by atomic absorption spectrophotometer. Newborn having any medical illness, on medication, with anaemia (Hb <10 gm/dl) excluded...
Unexpected focal colorectal fluorodeoxyglucose (FDG) uptake is becoming a common clinical dilemma with the increasing utilization of positron emission tomography (PET). These findings may subsequently reveal malignant or premalignant pathology.In addition to reporting prevalence clinically significant colonic pathology associated unexpected FDG uptake, this study analysed correlation between pathological segments those reported on FDG-PET scan.The reports 2071 consecutive PET-computed...
Esthesioneuroblastoma is rare, with limited therapeutic options when unresectable or metastatic; however, expression of somatostatin receptors qualifies it for peptide receptor radionuclide therapy (PRRT). We report outcomes PRRT in esthesioneuroblastoma from 2 referral centers. <b>Methods:</b> Using databases at European Neuroendocrine Tumor Society Centers Excellence, cases were sought between 2004 and 2018 patients who had recurrent metastatic deemed unsuitable further conventional...
Management of malignant insulinoma (MI) presents dual management challenges hypoglycaemia and tumour control. This study aims to analyse long-term outcomes PRRT for treatment MI. We retrospectively reviewed consecutive patients with MI treated [177Lu]Lu-DOTATATE (LuTATE) at two Australian NET centres between 2004-2022. Follow-up hypoglycaemia, molecular imaging, radiologic biochemical responses, treatment-related side-effects, progression free- overall-survival were assessed. Of 15 (7...
5010 Background: Terbium-161 ( 161 Tb) is a novel radionuclide emitting beta-radiation comparable to lutetium-177 177 Lu), with additional higher-energy, ultra-short path-length Auger electrons which may better target micrometastases. Tb has superior in-vitro and in-vivo efficacy in comparison Lu. We aim evaluate the safety effectiveness of [ Tb]Tb-PSMA-I&T patients metastatic castration-resistant prostate cancer (mCRPC). Methods: Eligible this investigator-initiated, single-centre,...
Abstract Background and objective There is widespread adoption of FDG ‐ PET/CT in staging lung cancer, but no universally accepted criteria for classifying thoracic nodes as malignant. Previous studies show high negative predictive values, reporting positive values varies. Using Endobronchial ultrasound transbronchial needle aspiration ( EBUS TBNA ) results gold standard, we evaluated interpreting mediastinal hilar compared this to expert visual interpretation EVI ). Methods A retrospective...
The appearance of rare ovarian germ cell tumors such as adult granulosa tumor (GCT) on F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) is reported in this article. We present a patient with recurrent GCT and histologically proven intra-abdominal metastases. Most lesions were above PET resolution (>1 cm). local recurrence demonstrated moderate FDG uptake but metastases had variable (none to mild) avidity. Ovarian GCTs are relatively low metastatic potential frequently solid...
Periodontal tissues mount an immune inflammatory response to bacteria and their products. Certain cytokines produced during periodontal inflammation increase the production of acute phase proteins like high‑sensitivity C‑reactive protein (hs‑CRP) can depress erythropoietin leading development anemia.The aim this study is investigate efficacy nonsurgical therapy on red blood cell (RBC) parameters hs-CRP in chronic periodontitis patients with anemia.This a longitudinal, interventional 6-month...
Objectives Surgery is the primary treatment modality for node-positive cutaneous squamous cell carcinoma of head and neck with no distant disease (HNcSCC-M0). The role preoperative positron emission tomography/computed tomography (PET/CT) scan these patients unclear. We compared PET/CT final histopathology among undergoing lymphadenectomy and/or parotidectomy HNcSCC-M0. Study Design Case series chart review. Setting Single Australian center. Subjects Methods Investigation included parameters...
Allopathic medications used for periodontal disease are known to be associated with various side effects. Hence a search naturotherapies on the rise. Among natural pharmacons available aloevera and propolis considered effective free from adverse Taking this into account, present study was done compare plaque inhibiting efficacies of Aloe vera Propolis tooth gels in patients chronic periodontitis.Forty diagnosed periodontitis were randomly allocated groups A B containing 20 each. Patients...
A 56-year-old patient was referred for FDG PET/CT with a right preauricular lymph node fine-needle biopsy, suggesting poorly differentiated carcinoma and no obvious primary lesion. There intense uptake in the nodule. The excised, formal histology demonstrated benign pilomatricoma rather than malignancy. Pilomatricoma is uncommon adults an unusual cause marked uptake, likely due to foreign body inflammation. can be either or malignant. our also suggests that PET cannot reliably grade this...
There is evidence that the status of human papilloma virus subtype 16 (HPV-p16) alters prognosis patients with oropharyngeal squamous cell cancer (OSCC). We sought to establish whether there a relationship between HPV-p16 and 18F-FDG uptake in OSCC.Patients newly diagnosed OSCC at our institution June 2011 2012 were retrospectively evaluated. All underwent baseline PET/computed tomographic scan testing. Tumour maximum standardized value (SUVmax), mean (SUVmean) total glycolytic activity...
Focal myositis is a rare benign inflammatory pseudotumor that can mimic malignancy, clinically and on imaging. A 34-year-old man presented with 3-week history of sudden-onset, nontender, left upper neck mass was nonresolving antibiotics. Anatomical imaging concerning for sarcoma the sternocleidomastoid muscle possible regional nodal metastases surrounding change. F-FDG PET/CT showed marked FDG uptake extending around anterior border no FDG-avid local disease. Core biopsy adjacent node...
The aim of this study is to assess the comparability and interchangeability radionuclide glomerular filtration rate (GFR) using different published techniques, propose normative data for paediatrics.A total 476 paediatric oncology patients aged 2-17 years, referred between January 2001 December 2008 GFR estimation, were reviewed any potential cause renal impairment. Sixty-nine met stringent inclusion criteria, included in study. estimation was carried out either technetium-99m diethylene...
Background Metastatic gastroenteropancreatic neuroendocrine neoplasms (GEPNEN) can cause ectopic Cushing’s syndrome (ECS). ECS is highly morbid and medical therapy complex be ineffective. Patients unsuitable for bilateral adrenalectomy (BA) have dismal outcomes. Peptide receptor radionuclide (PRRT) a rational option hormone disease control in caused by NEN with high somatostatin (SSTR) expression. Aim To describe the characteristics outcomes of patients treated PRRT. Methods Single-centre,...
A 76-year-old man was incidentally diagnosed with prostate lymphoma following transurethral resection of the for prostatism. Staging F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) revealed markedly increased FDG uptake in prostate, no evidence other disease. Following combination chemotherapy, restaging FDG-PET/CT demonstrated a complete metabolic response. The patient subsequently achieved prolonged remission on follow-up. Because its rarity, FDG-PET...