Qian Liu

ORCID: 0000-0001-7415-0798
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About
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Research Areas
  • Metamaterials and Metasurfaces Applications
  • Stroke Rehabilitation and Recovery
  • Oral microbiology and periodontitis research
  • Advanced Antenna and Metasurface Technologies
  • Orbital Angular Momentum in Optics
  • Periodontal Regeneration and Treatments
  • Polymer crystallization and properties
  • Immune Response and Inflammation
  • Dementia and Cognitive Impairment Research
  • Advanced Mathematical Physics Problems
  • Art Therapy and Mental Health
  • Acute Ischemic Stroke Management
  • Proteoglycans and glycosaminoglycans research
  • Mitochondrial Function and Pathology
  • Neonatal Respiratory Health Research
  • Antenna Design and Analysis
  • Natural Fiber Reinforced Composites
  • Music Therapy and Health
  • Neonatal and fetal brain pathology
  • Pregnancy-related medical research
  • Microwave Engineering and Waveguides
  • Atherosclerosis and Cardiovascular Diseases
  • Multicomponent Synthesis of Heterocycles
  • Medical and Biological Sciences
  • Microwave and Dielectric Measurement Techniques

Sichuan University
2009-2025

Chongqing Medical University
2025

West China Hospital of Sichuan University
2020-2024

West China Second University Hospital of Sichuan University
2022-2024

State Key Laboratory of Oral Diseases
2018-2023

Chengdu University of Information Technology
2020-2023

Shanghai University of Electric Power
2020

Southwest Minzu University
2005

Neuronal apoptosis is one of the main pathological processes hypoxic-ischemic brain damage (HIBD) and involved in development encephalopathy (HIE) neonates. Atorvastatin has been found to have neuroprotective effects some nervous system diseases, but its role regulating pathogenesis neonatal HIBD remains elusive. Thus, this study aimed explore related mechanisms atorvastatin on regulation neuronal after newborn rats. The rat model oxygen glucose deprivation (OGD) were established routinely....

10.1096/fj.202101654rr article EN The FASEB Journal 2022-03-18

Sepsis, a serious condition with high mortality, usually causes sepsis associated encephalopathy (SAE) that involves neuronal cell death. However, the death programs involved and their underlying mechanisms are not clear. This study aimed to explore regulatory of different in SAE.A neonatal rat model SAE was established by cecal ligation perforation. Survival rate vital signs (mean arterial pressure heart rate) were monitored, nerve reflexes evaluated, cortical pathological changes observed...

10.1097/cm9.0000000000002010 article EN cc-by-nc-nd Chinese Medical Journal 2022-03-09

Lipopolysaccharide (LPS)-induced inflammatory microenvironment can enhance the dental follicle cells (DFCs) proliferation, differentiation, and adhesion abilities beneficial to periodontal regeneration, which possibly attributes success exosomes according recent studies. This study aimed investigate therapeutic efficacy underlying mechanisms of LPS-preconditioned DFC-derived small extracellular vesicles (sEVs), enriched for regeneration in an microenvironment. LPS preconditioning could...

10.1021/acsbiomaterials.0c00882 article EN ACS Biomaterials Science & Engineering 2020-09-11

Dental follicle stem cells (DFSCs) have been verified to promote periodontal regeneration in an inflammatory microenvironment. When coping with stimulation, DFSCs highly express periostin, a bioactive molecule closely related homeostasis. It is worth exploring whether and how periostin plays role the promotion of by DFSCs. By tracking fate DFSCs, it was found that significantly contributed rat defects while they had low survival rate. They expressed improved immune microenvironment defect...

10.3390/ijms24076353 article EN International Journal of Molecular Sciences 2023-03-28

Introduction Post-stroke movement disorders are common, especially upper limb dysfunction, which seriously affects the physical and mental health of stroke patients. With continuous development intelligent technology, robot-assisted therapy has become a research hotspot in rehabilitation patients recent years. Many scholars have also integrated with other interventions to improve outcomes. However, there is lack determine auxiliary intervention best. Therefore, this protocol aims guide...

10.1371/journal.pone.0304322 article EN cc-by PLoS ONE 2025-01-28

Macrophage inflammatory response is the key driver in atherosclerosis development. However, transcriptional remodeling of macrophage remains largely unknown. In this study, regulatory networks were constructed from human plaque microarray datasets. Differential analysis and subsequent machine learning algorithms used to identify regulons. Multiple immune cell inference methods (including CIBERSORT, ssGSEA, MCP-counter, xCell), single-cell RNA-seq plaques immunofluorescence mouse samples...

10.7150/ijbs.102675 article EN cc-by-nc International Journal of Biological Sciences 2025-03-31

Background Dementia have brought great challenges to patients, families and society. Numerous art therapies for patients with dementia been developed in recent years. However, it is still unclear which therapy represents the optimal strategy promoting physical mental health. Objectives To compare efficacy of various improving cognitive function, activity daily living, depression, anxiety, agitation behavior quality life, rank practice consideration. Methods A comprehensive literature search...

10.3389/fpsyt.2023.1072066 article EN cc-by Frontiers in Psychiatry 2023-01-25

Abstract Background The RNA m6A modification has been implicated in multiple neurological diseases as well macrophage activation. However, whether it regulates microglial activation during hypoxic-ischemic brain damage (HIBD) neonates remains unknown. Here, we aim to examine the is involved modulating HIBD. We employed an oxygen and glucose deprivation model for vitro studies a neonatal mouse of tissue was subjected RNA-seq screen significant changes mRNA regulator. Thereafter, performed...

10.1186/s40246-023-00527-y article EN cc-by Human Genomics 2023-08-25

Abstract Inflammatory reaction plays a key role in the pathogenesis of hypoxic-ischemic encephalopathy (HIE) neonates. Microglia are resident innate immune cells central nervous system and profoundly involved neuroinflammation. Studies have revealed that atorvastatin exerts neuroprotective effect by regulating neuroinflammation adult animal models brain stroke traumatic injury, but its regarding damage to developing remains unclear. This study aimed clarify mechanism on regulation microglia...

10.1007/s12035-023-03777-y article EN cc-by Molecular Neurobiology 2023-11-24

The converged vortex beam with a well-defined focal plane is an essential ingredient for trapping and rotating microparticles. Metasurfaces, two-dimensional metamaterials, provide ultra-compact flexible platform designing by integrating the functions of lens plate. A spin-defocused metasurface can further boost information capacity such as multiplexing helicity-dependent functionalities. Here we propose approach to realize metalenses that simultaneously focus terahertz (THz) waves orthogonal...

10.1364/ol.404436 article EN Optics Letters 2020-09-10

Abstract Background Although some studies suggest that robot-assisted technology can significantly improve upper limb function in stroke patients compared to traditional rehabilitation training, it is still necessary incorporate an auxiliary intervention alleviate negative emotions, thereby alleviating the post-stroke fatigue and encouraging actively respond rehabilitation. However, effect of unknown. Objective To evaluate reminiscent music therapy combined with elderly dysfunction. Methods...

10.1186/s12984-024-01315-y article EN cc-by Journal of NeuroEngineering and Rehabilitation 2024-01-30

It aims to explore the effect of dental follicle cells-derived small extracellular vesicles (D-sEVs) with or without lipopolysaccharides (LPS) pretreating on pathogenicity Porphyromonas gingivalis (P. gingivalis).The antibacterial effects D-sEV were evaluated by measuring growth, biofilm formation, gingipains, and type IX secretion system (T9SS) expression P. gingivalis. And influence adhesion, invasion, cytotoxicity, host immune response was examined in gingival epithelial cells (GECs)....

10.1111/odi.14239 article EN Oral Diseases 2022-05-05

The relationship between the density of entangled amorphous network and ductility oriented poly(l-lactide) (PLLA) films is explored based on preferential hydrolysis regions in phosphate buffer solution (PBS). PLLA with a balance stiffness have been prepared by "casting–annealing stretching" mechanical rejuvenation, structural evolution properties at different durations identified. Various stages are found during transition to brittleness for hydrolyzed films. First, elongation break remains...

10.1021/acs.biomac.3c00188 article EN Biomacromolecules 2023-06-05

Abstract A transmission phase‐shifted metasurface (PSM) array has been proposed for non‐diffractive beam deflection. PSM element consists of two identical semicircular rings and an I‐shaped structure, which is symmetrically printed on both sides the F4B substrate. According to geometric optics, phase distribution can be obtained. To achieve desired distribution, elements rotated at different angles are rearranged, since transmitted wave manipulated by rotating element. Then, standard horn...

10.1049/mia2.12235 article EN cc-by-nc-nd IET Microwaves Antennas & Propagation 2022-02-25

This cross-sectional study assessed early wound healing, pain intensity, quality of life, surgical satisfaction, and related factors during periodontal surgery.A total 369 patients completed the questionnaire before undergoing surgery (baseline), immediately after operation (phase I), on day suture removal II), one month later III). The Early Wound Healing Score (EHS) was assessed, short-form McGill Pain Questionnaire (SF-MPQ), tooth hypersensitivity visual analog scale (VAS), oral...

10.1186/s12903-022-02630-3 article EN cc-by BMC Oral Health 2022-12-10

A radial line slot array (RLSA) is proposed for Bessel-Gauss beam generation with a narrow main beamwidth and low sidelobe characteristics nonmetallic internal defects detection. Owing to the attenuation factor of Gaussian function, level can be suppressed. By accurately adjusting position size RLSA, optimum aperture field distribution synthesized generate near-field based on projection method. The simulated/measured results have shown that maximum nondiffraction distance 70 mm/70 mm...

10.1109/lawp.2021.3115166 article EN IEEE Antennas and Wireless Propagation Letters 2021-09-24

Introduction Subjective cognitive decline means a in the subjective perception of self-cognitive function, which is likely to evolve into mild impairment and dementia. The number elderly with has increased, bringing huge burdens challenges caregivers society. With increase research on art therapies, some them have gradually been proven be effective for function. Therefore, this study aims summarise evidence identify best therapy decline. Methods analysis We will include published randomised...

10.1136/bmjopen-2023-079146 article EN cc-by-nc BMJ Open 2024-04-01
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