A5018750682- Genetic and phenotypic traits in livestock
- Animal Genetics and Reproduction
- Monoclonal and Polyclonal Antibodies Research
- Animal Behavior and Welfare Studies
- Advanced Biosensing Techniques and Applications
- Genetic Mapping and Diversity in Plants and Animals
- Viral Infectious Diseases and Gene Expression in Insects
University of Zurich
2021-2023
Aspergillus niger is a filamentous fungus that extensively used in industrial fermentations for protein expression and the production of organic acids. Inherent biosynthetic capabilities, such as capacity to secrete these biomolecules high amounts, make A. an attractive host. Although renowned this ability, knowledge molecular components underlie its capacity, intercellular trafficking processes secretion mechanisms far from complete. Here, we introduce standardized set tools, consisting...
Colony management of gene-modified animals is time-consuming, costly and affected by random events related to Mendelian genetics, fertility litter size. Careful planning mandatory ensure successful outcomes using the least number animals, hence adhering 3R principles animal welfare. Here we have developed an R package, accessible also through interactive public website, that optimizes breeding design providing information about optimal breedings needed obtain defined outcomes, taking into...
Abstract Animal breeding is time-consuming, costly, and affected by stochastic events related to Mendelian genetics, fertility, litter size. Careful planning mandatory ensure a successful outcome using the least number of animals, hence adhering 3Rs animal welfare. We have developed an R package, accessible also through interactive website, that optimizes design provides comprehensive report suitable for any breeder genetically defined traits.