Kiyoshi Koyano

ORCID: 0000-0001-7459-0101
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About
Contact & Profiles
Research Areas
  • Dental Implant Techniques and Outcomes
  • Temporomandibular Joint Disorders
  • Bone Tissue Engineering Materials
  • Dental materials and restorations
  • Orthodontics and Dentofacial Orthopedics
  • Periodontal Regeneration and Treatments
  • Orthopaedic implants and arthroplasty
  • Dental Radiography and Imaging
  • Oropharyngeal Anatomy and Pathologies
  • Laser Applications in Dentistry and Medicine
  • Dysphagia Assessment and Management
  • Facial Nerve Paralysis Treatment and Research
  • Botulinum Toxin and Related Neurological Disorders
  • Endodontics and Root Canal Treatments
  • Bone health and treatments
  • Dental Health and Care Utilization
  • Oral microbiology and periodontitis research
  • dental development and anomalies
  • Oral and gingival health research
  • Bone Metabolism and Diseases
  • Dental Education, Practice, Research
  • Electrospun Nanofibers in Biomedical Applications
  • Mesenchymal stem cell research
  • Dental Research and COVID-19
  • Obstructive Sleep Apnea Research

Kyushu University
2015-2025

Kyushu Dental University
2009-2022

Kyushu University Hospital
2004-2019

Psychiatric Rehabilitation Association
2003-2016

Fukuoka Dental College
1999-2016

Malmö University
2016

Science Council of Japan
2016

Kyushu Institute of Technology
2014

Showa University
2013

Health & Life (Taiwan)
2010

To date, there is no consensus about the definition and diagnostic grading of bruxism. A written discussion was held among an international group bruxism experts as to formulate a suggest system for its operationalisation. The expert defined repetitive jaw-muscle activity characterised by clenching or grinding teeth and/or bracing thrusting mandible. Bruxism has two distinct circadian manifestations: it can occur during sleep (indicated bruxism) wakefulness awake bruxism). For...

10.1111/joor.12011 article EN Journal of Oral Rehabilitation 2012-11-04

Summary In 2013, consensus was obtained on a definition of bruxism as repetitive masticatory muscle activity characterised by clenching or grinding the teeth and/or bracing thrusting mandible and specified either sleep awake bruxism. addition, grading system proposed to determine likelihood that certain assessment actually yields valid outcome. This study discusses need for an updated has following aims: (i) further clarify 2013 develop separate definitions bruxism; (ii) whether is disorder...

10.1111/joor.12663 article EN cc-by-nc-nd Journal of Oral Rehabilitation 2018-06-21

Leptin is a hormone that regulates body weight homeostasis mainly via the hypothalamic functional leptin receptor Ob-Rb. Recently, we proposed taste organ new peripheral target for leptin. selectively inhibits mouse cell responses to sweet substances and thereby may act as modulator. The present study further investigated action on system by examining expression of Ob-Rb in cells behavioral leptin-deficient ob/ob, Ob-Rb-deficient db/db mice their normal litter mates. RT-PCR analysis showed...

10.1210/en.2003-0602 article EN Endocrinology 2003-11-03

summary This study investigated the effect of stabilization splint (SS) and palatal (PS), which had same design as SS except for elimination occlusal coverage, on sleep bruxism (SB) using a portable electromyographic (EMG) recording system. Sixteen bruxers participated in this study. The EMG activities right masseter muscle during were recorded three nights each following five periods: before, immediately after, 2, 4 6 weeks after insertion splint. crossover design, was applied to subject...

10.1111/j.1365-2842.2005.01576.x article EN Journal of Oral Rehabilitation 2006-02-13

It has recently been proposed that the peripheral taste organ is one of targets for leptin. In lean mice, leptin selectively suppresses gustatory neural and behavioral responses to sweet compounds without affecting other stimuli, whereas obese diabetic db/db mice with defects in receptor lack this suppression on taste. Here, we further examined potential links between humans.A total 91 nonobese subjects were used determine recognition thresholds using a standard stair-case methodology...

10.2337/db07-1103 article EN cc-by-nc-nd Diabetes 2008-07-16

Abstract Objectives: The aims of this study were to objectively assess bone quality with density values obtained by cone‐beam computed tomography (CBCT) and determine the correlations between primary stability dental implants. Material methods: Eighteen Straumann implants inserted into 18 fresh femoral heads swine. densities implant recipient sites preoperatively determined value using CBCT. maximum insertion torque each was recorded a digital meter. Resonance frequency, which represented...

10.1111/j.1600-0501.2011.02203.x article EN Clinical Oral Implants Research 2011-05-05

Abstract Objectives: Hydroxymethylglutaryl‐coenzyme A reductase inhibitors, the so‐called statins, have been widely used for hyperlipidemic patients, and it was recently reported that promoted bone formation. In present study, we examined effect of simvastatin on promotion osteogenesis around titanium implants. Materials methods: Ten 30‐week‐old rats received pure implants in both tibiae, were then divided into experimental control groups. The group administered daily. Thirty days later, all...

10.1046/j.1600-0501.2003.01015.x article EN Clinical Oral Implants Research 2004-04-02

Ketamine is an important analgesia clinically used for both acute and chronic pain. The analgesic effects of ketamine are generally believed to be mediated by the inhibition NMDA receptors in nociceptive neurons. However, neuronal cannot fully account its potent on pain because there a significant discrepancy between their potencies. possible effect spinal microglia was first examined hyperactivation after nerve injury contributes neuropathic Optically pure S -ketamine preferentially...

10.1523/jneurosci.4152-11.2011 article EN cc-by-nc-sa Journal of Neuroscience 2011-11-30

Abstract As osteoclasts have the central roles in normal bone remodeling, it is ideal to regulate only performing pathological destruction without affecting osteoclasts. Based on a hypothesis that form under microenvironment of tissues, we here set up optimum culture conditions examine entity pathologically activated (PAOCs). Through searching various inflammatory cytokines and their combinations, found highest resorbing activity when were formed presence M-CSF, receptor activator NF-κB...

10.4049/jimmunol.1602035 article EN The Journal of Immunology 2017-11-15

Summary This randomised controlled study investigated the effect of intermittent use occlusal splints on sleep bruxism compared with that continuous by measuring masseter muscle electromyographic activity using a portable recording system. Twenty bruxers were randomly allocated to group and group. Subjects in wore stabilisation during for 29 nights continuously, whereas those every other week, is they used 1st–7th, 15th–21st 29th nights. Electromyographic was recorded following six time...

10.1111/joor.12251 article EN Journal of Oral Rehabilitation 2014-11-01
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