- Obstructive Sleep Apnea Research
- Temporomandibular Joint Disorders
- Sleep and Wakefulness Research
- Dysphagia Assessment and Management
- Botulinum Toxin and Related Neurological Disorders
- Olfactory and Sensory Function Studies
- Voice and Speech Disorders
- Neuroscience of respiration and sleep
- Orthodontics and Dentofacial Orthopedics
- Transcranial Magnetic Stimulation Studies
- Vestibular and auditory disorders
- Pain Mechanisms and Treatments
- Neuroscience and Neuropharmacology Research
- Oropharyngeal Anatomy and Pathologies
- Restless Legs Syndrome Research
- Catalytic Processes in Materials Science
- Spatial and Panel Data Analysis
- Cleft Lip and Palate Research
- Sleep and related disorders
- Speech and Audio Processing
- Facial Nerve Paralysis Treatment and Research
- Metal-Organic Frameworks: Synthesis and Applications
- Time Series Analysis and Forecasting
- Biochemical Analysis and Sensing Techniques
- Salivary Gland Disorders and Functions
Osaka University
2016-2025
Juntendo University
2025
Fukuoka University
2013-2024
Osaka University Hospital
2015-2024
Osaka Dental University
1997-2023
Nagoya University
2008-2023
Kurashiki University of Science and the Arts
2007-2023
Denka (Japan)
2020-2021
Daiichi-Sankyo (Japan)
2015-2021
Bridge University
2018
To date, there is no consensus about the definition and diagnostic grading of bruxism. A written discussion was held among an international group bruxism experts as to formulate a suggest system for its operationalisation. The expert defined repetitive jaw-muscle activity characterised by clenching or grinding teeth and/or bracing thrusting mandible. Bruxism has two distinct circadian manifestations: it can occur during sleep (indicated bruxism) wakefulness awake bruxism). For...
Summary In 2013, consensus was obtained on a definition of bruxism as repetitive masticatory muscle activity characterised by clenching or grinding the teeth and/or bracing thrusting mandible and specified either sleep awake bruxism. addition, grading system proposed to determine likelihood that certain assessment actually yields valid outcome. This study discusses need for an updated has following aims: (i) further clarify 2013 develop separate definitions bruxism; (ii) whether is disorder...
Spontaneous rhythmic masticatory muscle activity (RMMA) during sleep occurs in relation to transient activation the cerebral and autonomic nervous systems of normal subjects patients with bruxism (SB). In this study, we made a quantitative assessment sequential changes cortical electroencephalographic (EEG) autonomic-cardiac activities associated micro-arousals preceding RMMA episodes. We matched 10 SB subjects. The onset episodes was defined terms suprahyoid muscles. patients, an increase...
Rhythmic Masticatory Muscle Activity (RMMA) is frequently observed during sleep in normal subjects and bruxers. We hypothesized that some exhibit RMMA at a lower frequency than Polysomnographic data from 82 were compared with 33 episodes defined as three or more consecutive bursts of masseter EMG activity, without tooth-grinding. Such nearly 60% subjects. A was noted Sleep organization similar between groups. Bruxers had twice many muscle per episode higher amplitude controls RMMA. The high...
Summary Sleep bruxism (SB) subjects show a higher incidence of rhythmic masticatory muscle activity (RMMA) than control subjects. RMMA is associated with sleep micro‐arousals. This study aims to: (i) assess RMMA/SB episodes in relation to cycles; (ii) establish if and micro‐arousals occur the slow wave (SWA) dynamics; (iii) analyze association between autonomic cardiac across cycles. Two nights polygraphic recordings were made three groups (20 each): moderate high SB, low SB control....
Spontaneous rhythmic masticatory muscle activity (RMMA) during sleep occurs more frequently following spontaneous transient micro-arousal in patients with bruxism (SB) and normal controls. Here, we tested the hypothesis that an experimental arousal would be followed by increase RMMA. We identified RMMA on polygraphic recordings taken before after sensory stimulation to induce eight SB matched subjects. The rate of level resting electromyographic masseter suprahyoid muscles did not differ...
To investigate the effects of botulinum toxin type A (BoNT-A) injection on jaw motor episodes during sleep in patients with or without orofacial pain who did not respond to oral splint treatment.Twenty subjects a clinical diagnosis SB completed this study. Ten received bilateral BoNT-A injections (25 U per muscle) into masseter muscles only (group A), and other 10 both temporalis B). Video-polysomnographic (vPSG) recordings were made before at 4 weeks after injection. Rhythmic masticatory...
Summary Rhythmic masticatory muscle activity (RMMA) is the characteristic electromyographic pattern of sleep bruxism (SB), a sleep‐related motor disorder associated with arousal. Sleep arousals are generally organised in clustered mode known as cyclic alternating (CAP). CAP expression instability between maintaining processes (phase A1) and stronger arousal (phases A2 A3). This study aimed to investigate role on RMMA/SB occurrence by analysing electroencephalographic (EEG) activities. The...
Sleep bruxism (SB) is reported to vary in frequency over time. The aim of this study was assess the first night effect on SB.
Abstract This exploratory observational study aimed to evaluate whether the blood levels of serotonin and enzymes involved in synthesis are associated with sleep breathing parameters. A total 105 patients were included this study, who subjected single-night polysomnography simultaneous audio–video recordings. Peripheral samples collected estimate serum serotonin, tryptophan hydroxylase 1 (TPH1), aromatic l-amino acid decarboxylase (AADC). Results showed a negative correlation between levels,...
To describe the relationships of sleep bruxism to swallowing and positions.Controlled descriptive study.Polysomnography audio-video recordings were done in a hospital laboratory.Nine patients with 7 normal subjects matched for age sex.n/a.During sleep, showed higher frequency rhythmic masticatory muscle activity episodes (6.8 +/- 1.0 [SEM]/h) than did normals (0.5 0.1/h, p < 0.01). Swallowing-related laryngeal movements occurred more frequently 0.8/h) (3.7 0.3/h, In both groups, during close...
To examine the relationships between masticatory force, electromyogram (EMG) of muscles, and jaw movement pattern, we quantitatively evaluated effects changing hardness a chewing substance on these three variables. Cortically induced rhythmic movements crescent-shaped pattern were by electrical stimulation cerebral cortical area in anesthetized rabbit. The axially directed force was recorded with small force-displacement transducer mounted ground surface lower molars. EMGs from masseter...
The literature on sensory perception during sleep suggests that light (Stage 2) is more responsive to external stimulation (e.g. sound, electrical shock) than deep (Stages 3 and 4) REM sleep. main objective of this study was characterize the specificity nociceptive trigger arousal-awakening over all stages. Thirteen healthy adults without pain or problems; six female seven male a mean age 24.2+/-1.3 years) were included in study. responses noxious intramuscular 5% hypertonic infusion...
Objectives:We aimed to characterize the association between jaw muscle contractions and respiratory events in patients with obstructive sleep apnea syndrome (OSAS) investigate responsiveness of comparison that leg muscles terms arousal types states.Methods: Polysomnographic (PSG) recordings were performed 19 OSAS (F/M: 2/17; 53.1 ± 13.7 years; AHI: 31.8 19.9/h) no concomitant bruxism or other sleep-related movement disorders.Muscle unilateral masseter (MAS) anterior tibialis (AT) scored...