A5004946983- Frailty in Older Adults
- Intensive Care Unit Cognitive Disorders
- Dementia and Cognitive Impairment Research
- Health Systems, Economic Evaluations, Quality of Life
- Long-Term Effects of COVID-19
- Health disparities and outcomes
- Emergency and Acute Care Studies
- Nutrition and Health in Aging
- COVID-19 and healthcare impacts
- Geriatric Care and Nursing Homes
- Chronic Disease Management Strategies
- Cardiac, Anesthesia and Surgical Outcomes
- Pharmaceutical Practices and Patient Outcomes
- Sepsis Diagnosis and Treatment
- COVID-19 and Mental Health
- Dialysis and Renal Disease Management
- Family and Patient Care in Intensive Care Units
- Muscle and Compartmental Disorders
- COVID-19 Clinical Research Studies
- Aging, Health, and Disability
- Health, Nursing, Elderly Care
- Balance, Gait, and Falls Prevention
- Health and Well-being Studies
- COVID-19 Impact on Reproduction
- Hemodynamic Monitoring and Therapy
Hospital Sírio-Libanês
2020-2025
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2020-2025
Universidade de São Paulo
2016-2025
Johns Hopkins University
2025
Universidade Brasil
2024
RELX Group (Netherlands)
2023
Peninsula Health
2022
Universidade Federal de São Carlos
2021
Insper
2020
University of California, San Francisco
2018-2019
Little is known about the association between acute mental changes and adverse outcomes in hospitalized adults with COVID-19.
BACKGROUND Physical frailty is a powerful tool for identifying nondisabled individuals at high risk of adverse outcomes. The extent to which cognitive impairment in those without dementia adds value physical detecting high‐risk remains unclear. OBJECTIVES To estimate the effects combining and (CIND) on basic activities daily living (ADL) dependence death over 8 years. DESIGN Prospective cohort study. SETTING Health Retirement Study (HRS). PARTICIPANTS A total 7338 community‐dwelling people,...
Frailty screening using the Clinical Scale (CFS) has been proposed to guide resource allocation in acute care settings during pandemic. However, association between frailty and coronavirus disease 2019 (COVID-19) prognosis remains unclear.To investigate mortality over 6 months middle-aged older patients hospitalized with COVID-19 morbidity severity across strata.Observational cohort study.Large academic medical center Brazil.A total of 1830 aged ≥50 years (March-July 2020).We screened...
As the pandemic advances, interest in long-lasting consequences of COVID-19 increases. However, a few studies have explored patient-centered outcomes critical care survivors. We aimed to investigate frailty and disability transitions patients admitted ICUs.Prospective cohort study.University hospital Sao Paulo.Survivors ICU admissions.None.We assessed using Clinical Frailty Scale (CFS). also evaluated 15 basic, instrumental, mobility activities. Baseline were defined by clinical conditions...
While efforts have been made to validate intrinsic capacity (IC) as a multidimensional indicator of healthy aging in high-income countries, we still need evidence from lower-income countries. We examined associations IC with wide ranges activities daily living nationally representative sample Brazilians aged≥50 years.This cross-sectional analysis included 7175 participants the Brazilian Longitudinal Study Aging. domains (cognitive, psychological, sensory, locomotor, and vitality) were...
ABSTRACT Background Existing risk scores assessing geriatric vulnerability in the emergency department (ED) have shown limited predictive power, especially diverse populations. We investigated relationship of a quick and easy‐to‐administer scoring system with functional decline mortality older patients admitted to multiple hospitals through ED United States (US) Brazil (BR). Method Federated, international, multicenter observational study hospitalized aged ≥ 65 from US BR. The six criteria...
Abstract Background Although frailty has been associated with atypical manifestations of infections, little is known about COVID-19 presentations in hospitalized frail patients. We aimed to investigate the association between age, frailty, and clinical characteristics middle-aged older adults. Method Longitudinal observational study comprising 711 patients aged ≥50 years consecutively admitted a university hospital dedicated severe cases, March May 2020. reviewed electronic medical records...
Abstract Background Approximately 77% of older adults with dementia in Brazil have not been diagnosed, indicating a major public health issue. Previous epidemiological studies were based on data from 1 geopolitical region. Methods We aimed to estimate the general and subgroup-specific (age, education, sex) prevalence cognitive impairment no (CIND) classification using 5 249 participants aged 60 years ELSI-Brazil, large nationally representative sample. Participants classified as having...
Abstract Background Although dementia has emerged as an important risk factor for severe SARS-CoV-2 infection, results on COVID-19-related complications and mortality are not consistent. We examined the clinical presentations outcomes of COVID-19 in a multicentre cohort in-hospital patients, comparing those with without dementia. Methods This retrospective observational study comprises laboratory-confirmed patients aged ≥ 60 years admitted to 38 hospitals from 19 cities Brazil. Data were...
Abstract Background Although coronavirus disease 2019 (COVID-19) disproportionally affects older adults, the use of conventional triage tools in acute care settings ignores key aspects vulnerability. Objective This study aimed to determine usefulness adding a rapid vulnerability screening an illness acuity tool predict mortality hospitalised COVID-19 patients. Design Cohort study. Setting Large university hospital dedicated providing care. Participants included are 1,428 consecutive...
Rationale: Recent reports suggest that patients with severe coronavirus disease (COVID-19) often experience long-term consequences of the infection. However, studies on intensive care unit (ICU) survivors are underrepresented. Objectives: We aimed to explore 12-month clinical outcomes after critical COVID-19, describing longitudinal progress disabilities, frailty status, frequency cognitive impairment, and events (rehospitalization, institutionalization, falls). Methods: performed a...
Abstract Introduction Cognitive impairment is common after severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. However, associations between post‐hospital discharge risk factors and cognitive trajectories have not been explored. Methods A total of 1105 adults (mean age ± SD 64.9 9.9 years, 44% women, 63% White) with disease 2019 (COVID‐19) were evaluated for function 1 year hospital discharge. Scores from tests harmonized, clusters defined using sequential analysis....
Objectives To develop and examine the validity reliability of a targeted geriatric assessment (TaGA) for busy healthcare settings. Design The TaGA was developed through consensus experts (Delphi technique), we investigated its construct in cross‐sectional study. Setting Geriatric day hospital specializing acute care Brazil. Participants Older adults (N = 534) aged 79.5 ± 8.4, 63% female, consecutively admitted to hospital. Measurements Frailty Index (FI), Physical Phenotype, Identification...
Abstract Background Despite the increasing knowledge about Covid-19 manifestations, there is still a lack of studies regarding impact pandemic in patients with dementia. This study aims to evaluate clinical characteristics and outcomes dementia hospitalized due Covid-19. Methods retrospective observational part multicentric cohort that analyzed data from 38 hospitals 19 Brazilian cities. Patients were included if they ≥ 60 years old laboratory-confirmed between March 2020 2022. Demographics...
ABSTRACT Objectives As the global dementia crisis intensifies, especially in low‐and middle‐income countries (LMICs), there is a pressing need for comprehensive prevalence data across diverse regions, including Brazil, where studies have been predominantly limited to affluent urban centers. This study aimed conduct an expert consensus determine of all‐cause considering various age groups, sexes, and geographical areas. Methods A Delphi process with clinical academic experts from Brazil was...
Objectives To investigate the association between loneliness and intrinsic capacity, a multidimensional indicator of healthy ageing, in Brazilians aged ≥50 years.